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Samaritan Pharmaceuticals granted IND from FDA for HIV drug

Samaritan Pharmaceuticals has announced that it has filed an IND (Investigational New Drug) application for SP-6310 in the treatment of HIV-infected patients with abnormal cortisol levels.

8 Jul 2008

UV light therapy is as beneficial for darker skin as lighter skin

An analysis of more than 100 patients has confirmed for the first time that darker-skinned patients benefit as those with lighter skin when given light therapy for morphea and related diseases, UT Southwestern Medical Center researchers show.

8 Jul 2008

Pregnancy increases risk of acute myocardial infarction

Although acute myocardial infarction (AMI) is rare in women of child-bearing age, pregnancy can increase a woman's risk of heart attack 3- to 4-fold, according to a study published in the July 15, 2008, issue of the Journal of the American College of Cardiology.

8 Jul 2008

A paradigm shift for targeted cancer therapy

We already know that recycling benefits our planet; and now new research suggests that the cellular version might be useful for battling cancer.

8 Jul 2008

Discovery of new function for an old enzyme in sialidosis

The lack of a single protein usually thought of as a run-of-the-mill enzyme that helps to recycle molecules in cells causes an incurable and often fatal disease of children, according to St. Jude Children's Research Hospital investigators.

7 Jul 2008

New ovarian stimulation technique helps women restore their fertility following chemotherapy or radiotherapy

Researchers have shown for the first time that it is possible to stimulate a woman's ovaries to produce eggs for collection during the final phase of the menstrual cycle.

7 Jul 2008

Experts say cognitive behavioural therapy effectiveness a 'myth'

According to experts the effectiveness of cognitive behavioural therapy (CBT) is a myth, and it is in no way superior to other methods.

7 Jul 2008

Gene change sheds light on sex development disorder

One in 4,500 people suffer from a group of conditions known as sex development disorders (DSD) which occur when the sex chromosomes do not match the genitalia.

7 Jul 2008

Treatment delays result in poor outcomes for men with breast cancer

Men who develop breast cancer are often not treated until the disease has spread to the point that treatment becomes difficult, new results show.

6 Jul 2008

Counting tumor cells in blood predicts treatment benefit in prostate cancer

Counting the number of tumor cells circulating in the bloodstream of patients with castration-resistant prostate cancer can accurately predict how well they are responding to treatment, new results show.

6 Jul 2008

Modified chemotherapy regimen promising for lymphoma patients in the developing world

Preliminary results suggest that patients with aggressive non-Hodgkin's lymphoma in the developing world might benefit from a modified chemotherapy regimen, researchers say.

6 Jul 2008

Researchers solve structure of proteins known as sodium glucose co-transporters

Researchers at the David Geffen School of Medicine at UCLA have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells.

4 Jul 2008

Scientists discover way to protect against death following plague infection

Bacteria that cause pneumonic plague can evade our first-line defences, making it difficult for the body to fight infection. In fact, a signature of the plague is the lack of an inflammatory response.

3 Jul 2008

Canadian case of foreign-accent syndrome after stroke

A woman in southern Ontario is one of the first cases in Canada of a rare neurological syndrome in which a person starts speaking with a different accent, McMaster University researchers report in the July issue of the Canadian Journal of Neurological Sciences.

3 Jul 2008

Scientists shed new light into early mechanisms governing cardiovascular specification

The mature heart is composed by different cell types, including contractile cardiac cells, vascular cells, smooth muscle cells as well as pacemaker cells.

3 Jul 2008

Safer, more effective stents will be available next week for patients with clogged arteries

Wake Forest University Baptist Medical Center will be one of the first medical centers in the region to begin using a new generation of drug-coated stents next week following a major study and the Food and Drug Administration's approval of their use.

3 Jul 2008

Study examines death rates for people newly diagnosed with HIV

In the five years after their diagnosis, people living with HIV in developed countries and receiving highly active antiretroviral therapy are no more likely to die than HIV-negative people, according to a study published Tuesday in the Journal of the American Medical Association, Reuters reports (Kahn, Reuters, 7/1).

3 Jul 2008

Microchip-based device determines the genetic signature of lung tumors

Massachusetts General Hospital (MGH) investigators have shown that an MGH-developed, microchip-based device that detects and analyzes tumor cells in the bloodstream can be used to determine the genetic signature of lung tumors, allowing identification of those appropriate for targeted treatment and monitoring genetic changes that occur during therapy. A pilot study of the device called the CTC-chip will appear in the July 24 New England Journal of Medicine and is receiving early online release.

3 Jul 2008

New understanding of how herpes simplex virus 1 hides during inactive phase

Now that Duke University Medical Center scientists have figured out how the virus that causes cold sores hides out, they may have a way to wake it up and kill it.

3 Jul 2008

Computational research hones cancer-fighting strategies

A Florida State University faculty member who uses computational techniques to evaluate a new class of cancer-killing drugs is attracting worldwide attention from other researchers.

3 Jul 2008