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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

New compound ruboxistaurin may decrease vision loss in diabete

A multicenter international study chaired by a Joslin Diabetes Center investigator and reported in the July issue of the American Diabetes Association's journal Diabetes brings hopeful news to the 18 million people in the United States -- and millions more worldwide -- with type 1 or type 2 diabetes.

15 Jul 2005

Novel way in which the brain size of developing mammals may be regulated

Howard Hughes Medical Institute researchers have discovered a novel way in which the brain size of developing mammals may be regulated. They have identified a signaling pathway that controls the orientation in which dividing neural progenitor cells are cleaved during development.

14 Jul 2005

Complicated plasminogen system yields potential therapeutic target; Implications for aging and degenerative diseases

Skeletal muscles naturally repair themselves very efficiently after injury. But when they don’t, otherwise successful recovery following damage from overuse during exercise, surgery or trauma can be stymied. Furthermore, as we age, muscle repair slows noticeably, and in Duchenne Muscular Dystrophy and other degenerative muscle diseases, normal repair functions can’t cope with disease progression.

14 Jul 2005

Erlotinib increases survival in patients with advanced non-small cell lung cancer

An international clinical study led by Canadian researchers has demonstrated that a drug called erlotinib increases survival in patients with advanced non-small cell lung cancer who typically have no other treatment options.

13 Jul 2005

Transplanted neural stem cells may serve not only as replacement cells for tissue repair, but in some circumstances may also protect the brain from inflammation

Researchers at the San Raffaele Hospital (Milan, Italy) published unexpected results of studies in which immature nerve cells (adult mouse neural stem cells) injected into the blood of mice with MS-like disease were able to suppress the immune attacks that damage the brain and spinal cord tissues.

13 Jul 2005

Researchers gain better understanding of how nerves need to be reconnected after spinal cord injury

Nerve cells relay messages at blink-of-the-eye speeds by squirting chemicals called neurotransmitters across tiny gaps called synapses to awaiting message receptors. But lots of different receptors and neurotransmitters work simultaneously. Which goes where to send the proper message?

13 Jul 2005

White blood cell called a neutrophil appears to be crucial to abdominal aortic aneurysm formation

Each year, 200,000 Americans find out that the largest blood vessel in their body, the aorta, may burst open at any time. About 20,000 die suddenly from such a rupture. And another 36,000 have surgery to repair or replace the swelling section of aorta before time runs out.

13 Jul 2005

Stressgen granted U.S. patent providing coverage for the manufacture of HspE7

Stressgen Biotechnologies announced today that the U.S. Patent and Trademark Office granted US Patent Number 6,900,035, covering methods of manufacturing HspE7, the Company's lead product candidate for human papillomavirus (HPV)- related diseases and cancer.

13 Jul 2005

Research shows key difference between the eye's light-detecting system and the nose's odor-detecting system

Johns Hopkins scientists have uncovered new details of how smelly things create signals in the nose that eventually go to the brain. The findings raise issues about how the process involved has been described for many years in biology textbooks.

13 Jul 2005

Researchers modify software to predict gene transcription

A modification to an "ace" gene prediction program by computer scientists at Washington University in St. Louis now enables scientists to predict the very beginnings of gene transcription start sites and where the first splice occurs thereby defining the first exon of the gene.

13 Jul 2005

Protein News and Research

Further Reading

New compound ruboxistaurin may decrease vision loss in diabete

Novel way in which the brain size of developing mammals may be regulated

Complicated plasminogen system yields potential therapeutic target; Implications for aging and degenerative diseases

Erlotinib increases survival in patients with advanced non-small cell lung cancer

Transplanted neural stem cells may serve not only as replacement cells for tissue repair, but in some circumstances may also protect the brain from inflammation

Researchers gain better understanding of how nerves need to be reconnected after spinal cord injury

White blood cell called a neutrophil appears to be crucial to abdominal aortic aneurysm formation

Stressgen granted U.S. patent providing coverage for the manufacture of HspE7

Research shows key difference between the eye's light-detecting system and the nose's odor-detecting system

Researchers modify software to predict gene transcription

If strawberries weren't red they wouldn't cause allergies

Serotonin may play a role in maintaining circadian rhythm

Curcumin has potent anticancer powers

Researchers have pinpointed specific gene and protein over-production in metastatic melanoma

X-ray crystallography images show how a protein called alpha-actinin performs molecular ballet

Discovery of protein deficit that causes drug toxicity

Keap1 protein - a promising new target for drugs to fight many different kinds of cancer

New understanding of degeneration of brain cells in patients with Alzheimer's, Huntington's, and Parkinson's diseases

Researchers have discovered how p16 gene works

Lack of a blood clotting protein may protect against clogged arteries

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