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Researchers identify risk factors, protective medication for people living with lupus

According to research presented this week at the American College of Rheumatology Annual Meeting in San Diego, researchers have identified three potentially modifiable risk factors and one protective medication that may improve the health of people living with lupus.

28 Oct 2013

Study reveals that Medicaid beneficiaries with lupus not following treatment plans

Medicaid beneficiaries with lupus are not adequately following their treatment plans, and this puts them at risk for poor health outcomes, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego. For most lupus medications, fewer than one in three beneficiaries were found to be adherent.

28 Oct 2013

Self-directed walking program shows promise in easing joint stiffness in older breast cancer patients

A self-directed walking program shows promise in easing joint stiffness in older women who experienced these symptoms while taking aromatase inhibitor therapy for breast cancer, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Young, middle-aged fibromyalgia patients report poorer quality of life than older patients

It may seem counterintuitive, but young and middle-aged fibromyalgia patients report worse symptoms and poorer quality of life than older patients, a Mayo Clinic study shows.

28 Oct 2013

Children born to mothers with lupus have twice the risk of autism spectrum disorders

According to research presented this week at the American College of Rheumatology Annual Meeting in San Diego, children born to mothers with lupus may be at twice the risk of autism spectrum disorders than those born to mothers without the disease.

28 Oct 2013

Lupus disparities: Young, black women have highest rate of developing lupus

Young, black women have the highest rate of developing lupus and are most likely to be diagnosed at a younger age than whites and during childbearing years, according to a new University of Michigan study of lupus in Southeastern Michigan.

25 Oct 2013

New flu vaccine offers better protection against circulating flu viruses

Last year's flu season was considered one of the strongest and deadliest in recent decades, according to the CDC. In preparation for this year's flu season, Concentra, a subsidiary of Humana Inc., offers a flu vaccine to provide greater protection against circulating flu strains.

23 Oct 2013

New PARP inhibitor shows early responses in patients with advanced BRCA-related cancers

An investigational new PARP inhibitor, BMN 673, is showing early responses in patients with heavily pretreated, advanced, BRCA-related cancers of the breast and ovary, according to phase I clinical trial results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

23 Oct 2013

Angiochem presents results of Phase 2 study with ANG1005 in breast cancer patients with brain metastases

Angiochem, a clinical stage biotechnology company developing drugs that are uniquely capable of crossing the blood-brain barrier (BBB), announced that the complete analysis results of a Phase 2 clinical study with ANG1005, a novel paclitaxel-peptide drug conjugate, in breast cancer patients with brain metastasis were presented today at the 2013 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference.

23 Oct 2013

Pfizer announces top-line results from phase 3b studies with Lyrica Capsules

Pfizer Inc. (NYSE:PFE) announced top-line results from two phase 3b, placebo-controlled studies with Lyrica® (pregabalin) Capsules CV in patients with fibromyalgia (FM) and painful diabetic peripheral neuropathy (DPN), respectively.

19 Oct 2013

Diaphragm pacing systems improve quality of life for ALS patients

Respiratory failure is one of the major complications associated with amyotrophic lateral sclerosis. The quest for alternative approaches for treating respiratory failure has led to the study, and subsequent FDA approval, of diaphragm pacing for use in ALS patients. However, there are still important unanswered questions about its benefit and impact.

18 Oct 2013

NEJM publishes Celgene’s Abraxane phase III study results

Published today in the New England Journal of Medicine, a phase III clinical trial of Abraxane (paclitaxel formulated as albumin-bound nanoparticles) in combination with gemcitabine in treatment-naive patients with metastatic pancreatic cancer demonstrated a statistically significant improvement in overall survival compared to patients receiving gemcitabine alone [(median of 8.5 vs. 6.7 months) (HR 0.72, P=0.000015)].

17 Oct 2013

Study focuses on vaccine-preventable illnesses in myasthenia gravis patients

A study presented at the annual meeting of the American Association of Neuromuscular & Electrodiagnostic Medicine is considered a good first step in collecting data on vaccine-preventable illnesses in patients with myasthenia gravis, a neuromuscular disorder causing weakness and rapid fatigue of voluntary muscles.

17 Oct 2013

Non-Hispanic black, Hispanic patients less likely to experience metabolic syndrome remission

The impact of bariatric surgery on risk factors for cardiovascular disease depends on a variety of factors, including the type of surgery, sex of the patient, ethnic background, and pre-surgery body mass index, according to a Kaiser Permanente study published today in Annals of Surgery.

16 Oct 2013

UC researchers receive $2.1M grant from NIH to study molecular mechanisms of muscle fatigue

University of Cincinnati (UC) researchers have been awarded a five-year, $2.1 million grant from the National Institutes of Health (NIH) to study an isoform that plays a critical role in human resistance to fatigue.

16 Oct 2013

Research shows age does not affect symptom recovery after sports-related concussion

Recent scientific findings have raised the fear that young athletes may fare worse after sustaining a sports-related concussion than older athletes.

15 Oct 2013

Results announced for Phase II PRECEDENT trial of vintafolide for treatment of platinum-resistant ovarian cancer

Merck, known as MSD outside the United States and Canada, (NYSE: MRK) and Endocyte, Inc. (NASDAQ: ECYT) today announced the online publication of results from the randomized Phase II PRECEDENT trial for vintafolide (MK-8109/EC145), an investigational folate small molecule drug conjugate (SMDC), in the Journal of Clinical Oncology (JCO), the official journal of the American Society of Clinical Oncology.

15 Oct 2013

Baylor provides AED demonstrations on how to save people who experience sudden cardiac arrest

Exiting an elevator, a man crumples to the floor just outside the elevator. You, an innocent bystander, freeze. Then, you see the glass case on the wall with the heart and lightening decal. Whether or not you reach for that case and open it is a life or death decision for the stranger lying at the elevator doors.

15 Oct 2013

Sleep duration negatively impacts on self-rated health

Individuals who experience long or short sleep durations are more likely to report poor self-rated health than healthy sleepers, Korean study findings suggest.

14 Oct 2013

IV lidocaine infusion provides significant pain relief to fibromyalgia patients

Patients with fibromyalgia resistant to more routine therapies have a new pain relief treatment available, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

14 Oct 2013

Fatigue News and Research

Researchers identify risk factors, protective medication for people living with lupus

Study reveals that Medicaid beneficiaries with lupus not following treatment plans

Self-directed walking program shows promise in easing joint stiffness in older breast cancer patients

Young, middle-aged fibromyalgia patients report poorer quality of life than older patients

Children born to mothers with lupus have twice the risk of autism spectrum disorders

Lupus disparities: Young, black women have highest rate of developing lupus

New flu vaccine offers better protection against circulating flu viruses

New PARP inhibitor shows early responses in patients with advanced BRCA-related cancers

Angiochem presents results of Phase 2 study with ANG1005 in breast cancer patients with brain metastases

Pfizer announces top-line results from phase 3b studies with Lyrica Capsules

Diaphragm pacing systems improve quality of life for ALS patients

NEJM publishes Celgene’s Abraxane phase III study results

Study focuses on vaccine-preventable illnesses in myasthenia gravis patients

Non-Hispanic black, Hispanic patients less likely to experience metabolic syndrome remission

UC researchers receive $2.1M grant from NIH to study molecular mechanisms of muscle fatigue

Research shows age does not affect symptom recovery after sports-related concussion

Results announced for Phase II PRECEDENT trial of vintafolide for treatment of platinum-resistant ovarian cancer

Baylor provides AED demonstrations on how to save people who experience sudden cardiac arrest

Sleep duration negatively impacts on self-rated health

IV lidocaine infusion provides significant pain relief to fibromyalgia patients

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