Hypertension (High Blood Pressure) News and Research

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Hypertension (or high blood pressure) is a condition where the pressure of the blood flowing through the arteries of the body is higher than it should be. Much like the pressure of the air in a tire, if the pressure of the blood is too high it can damage the arteries and organs of the body. Just like the tire, if the pressure suddenly becomes very high, catastrophic events can happen. Similarly, if the pressure remains somewhat elevated for a long enough period of time, premature wear and failure can occur.

Hypertension has its worst effects on the heart, kidneys, eyes, and brain. High blood pressure is a risk factor for heart attack, stroke, kidney failure, hemorrhages of the retina of the eye, and generalized atherosclerosis (hardening of the arteries all over the body).

The costs of caring for elderly patients hospitalized for colon surgery are not reduced by Medicare HMOs

The costs of caring for elderly Florida patients hospitalized for colon surgery are not reduced by Medicare HMOs, report University of South Florida researchers in the December issue of the Archives of Surgery.

21 Dec 2004

10 to 20 million people in the United States have chronic kidney disease but most don’t know it

10 to 20 million people in the United States have chronic kidney disease but most don’t know it, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Center for Health Statistics.

19 Dec 2004

Obesity drug codenamed AOD9604 highly successful in trials

An Australian-owned obesity drug, developed by Melbourne-based biotechnology company Metabolic Pharmaceuticals Limited, is set to enter final human trials next year after successfully completing a Phase 2b human trial which proved that the drug induces weight loss and is very well tolerated with no evidence of the side effects commonly experienced with existing obesity drugs.

16 Dec 2004

Low-dose diuretic therapy for most patients with hypertension recommended

Patients with high blood pressure who take calcium channel blockers and diuretics have an increased risk for cardiovascular disease (CVD) death compared to patients who take beta-blockers plus diuretics, according to a study in the current issue of JAMA.

16 Dec 2004

Successful human trial of obesity drug that mimicks metabolic effects of growth hormone

The AOD9604 molecule is a small orally active peptide modelled on one section of the human growth hormone molecule. Growth hormone naturally occurs in the body and has profound stimulatory effects on fat metabolism, with levels of the hormone typically becoming suppressed in the obese state.

13 Dec 2004

Existing salt and hypertension guidelines obsolete

A respected medical expert has branded as "obsolete" and "one-sided" the existing salt and hypertension guidelines of Europe and the United States.

13 Dec 2004

Obesity rate among American workers of all ages grew from 20% to 29% over the past decade

The obesity rate among American workers of all ages grew from 20% to 29% over the past decade, leading to serious repercussions in the workplace and a demand for solutions, according to a new Pfizer Inc study published today in the Journal of Occupational and Environmental Medicine.

13 Dec 2004

Excellent news for the many people who suffer from high blood pressure

An international trial comparing blood-pressure lowering treatments has been stopped early due to the significantly better performance of one of the treatments in the trial.

8 Dec 2004

Resveratrol antioxidant found in red wine may benefit heart tissue

New research on rat heart cells suggests that a well-known antioxidant found in red wine, called resveratrol, may benefit heart tissue by limiting the effects of a condition called cardiac fibrosis.

8 Dec 2004

New advances in sickle cell disease

Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.

6 Dec 2004

Pfizer submits regulatory filings for Revatio (sildenafil citrate) as a treatment for pulmonary arterial hypertension

Sildenafil is the active ingredient in Viagra, Pfizer's erectile dysfunction medication used by more than 23 million men worldwide.

4 Dec 2004

Small social circles tied to heart disease death in women

Women with suspected coronary artery disease and smaller social networks die at twice the rate of those who have a larger circle of social contacts, according to a new study.

1 Dec 2004

Higher incidence of rejection following early steroid withdrawal

A new study on early steroid withdrawal following liver transplantation found that there was a higher incidence of rejection and a lower incidence of glucose intolerance necessitating treatment for diabetes.

1 Dec 2004

Avastin plus Folfox4 chemotherapy significantly extends survival in second-line metastatic colorectal cancer

Genentech and Roche today announced that a randomized Phase III study of Avastin™ (bevacizumab) plus the FOLFOX4 chemotherapy regimen (oxaliplatin/5-FU/leucovorin), compared to FOLFOX4 alone, in second-line metastatic colorectal cancer patients achieved its primary endpoint of improving overall survival.

29 Nov 2004

FDA approves Remodulin for the treatment of pulmonary arterial hypertension

United Therapeutics Corporation announced today that the U.S. Food and Drug Administration (FDA) has issued an approval letter for the intravenous use of Remodulin based on data establishing its bioequivalence with the previously approved subcutaneous administration of Remodulin.

24 Nov 2004

Research looks at the relationship between fetal health during pregnancy and later development of the brain

A new Canada Research Chair (CRC) at The University of Western Ontario is studying the relationship between fetal health during pregnancy and later development of the brain.

24 Nov 2004

More muscle facilitates the ability to regulate blood pressure

People with more muscle than fat have increased ability to regulate their blood pressure in response to stress, according to a Medical College of Georgia study.

24 Nov 2004

Cells linked to asthma and eczema also help cure deadly illness in mice

Mast cells are immune cells known mostly for their unwanted effects: they cause the wheezing of asthma, the itching of eczema, the sneezing and runny nose of hay fever and, in extreme cases, the life-threatening shock of anaphylaxis.

20 Nov 2004

Computer vignette effective at measuring quality of physician practice

A new measurement tool called the computerized clinical vignette can help clinicians and policymakers assess and improve the quality of physician practice while potentially reducing costs, according to a study led by a researcher at the San Francisco VA Medical Center (SFVAMC).

16 Nov 2004