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Combined therapy extends survival of older patients with glioblastoma, clinical study shows

Treating older patients who have malignant brain cancer with the chemotherapy drug temozolomide plus a short course of radiation therapy extends survival by two months compared to treating with radiation alone, show clinical trial results published today in the New England Journal of Medicine.

15 Mar 2017

Children with mild eczema unlikely to benefit from antibiotics, study shows

Estimates suggest that 40 percent of eczema flares are treated with topical antibiotics, but findings from a study led by Cardiff University suggest there is no meaningful benefit from the use of either oral or topical antibiotics for milder clinically infected eczema in children.

14 Mar 2017

Case studies for the role of in-process particle measurement to complement traditional API dissolution studies

Quantifying tablet disintegration profiles in situ and in real time enables scientists to reliably understand the breakage and dispersion mechanisms that govern API release rates. This essential process knowledge can support the prediction of in vivo drug release profiles during formulation development, and help identify the root cause of inconsistencies during release testing.

From Mettler-Toledo International Inc. 14 Mar 2017

New approach shows promise to prevent, treat cholesterol gallstone disease

According to current estimates, 20 to 25 million Americans have or will develop gallstones, representing almost 15% of adults. Although only a small percentage of individuals with gallstones develop symptoms, more than 700,000 individuals annually undergo surgical gallbladder removal and many more take medications to manage the condition or undergo stone-dissolving procedures.

13 Mar 2017

Mite-proof covers may reduce severity of asthma exacerbations in allergic children

Bedcovers that form a barrier to house dust mites appear to reduce asthma flare-ups in children, according to new research published online, ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

From The University of Manchester 10 Mar 2017

Dental plaque DNA of Neandertals provides insights into behaviour, diet and medication

Ancient DNA found in the dental plaque of Neandertals - our nearest extinct relative - has provided remarkable new insights into their behaviour, diet and evolutionary history, including their use of plant-based medicine to treat pain and illness.

8 Mar 2017

Researchers develop skin tests, decision support tool to increase antibiotic use in hospitalized patients

Massachusetts General Hospital and Brigham and Women's Hospital investigators have developed two approaches to increasing the use of penicillins and cephalosporins - highly effective antibiotics that are not as problematic as many alternatives - in hospitalized patients previously believed to be allergic to penicillin.

7 Mar 2017

EuroPrevent 2017 to explore innovative ideas in preventive cardiology

Innovations to prevent heart disease will take centre stage at EuroPrevent 2017 in Malaga, Spain. EuroPrevent is the annual congress of the European Association of Preventive Cardiology, a registered branch of the European Society of Cardiology.

6 Mar 2017

Study finds link between vitamin D levels and severity of malabsorption issues

Natural health experts BetterYou have welcomed a recommendation by leading gastroenterology expert Isobel Mason, to take a vitamin D supplement to reduce Crohn’s flare-ups.

From BetterYou Ltd 3 Mar 2017

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers with few therapeutic options, according to a study to be published in Cancer Discovery.

3 Mar 2017

Tailored preventive oral health intervention improves cleanliness of teeth, dentures among older adults

A tailored preventive oral health intervention significantly improved the cleanliness of teeth and dentures among elderly home care clients.

1 Mar 2017

Researchers develop nerve wrapping nanofiber mesh to facilitate regeneration, restore function

A NIMS-Osaka University joint research team developed a mesh which can be wrapped around injured peripheral nerves to facilitate their regeneration and restore their functions.

28 Feb 2017

Early preventive dental care for Medicaid-enrolled children may lead to long-term treatment, study suggests

Research out of the University of Alabama at Birmingham School of Public Health suggests preventive dental care provided by a dentist for children before the age of 2 enrolled in Medicaid in Alabama may lead to more care long-term.

28 Feb 2017

Universal public coverage of essential medicines could save over $4 billion per year, study finds

Universal public coverage of 117 essential medicines could address the needs of most Canadians for pharmaceutical drugs, and possibly save more than $4 billion a year, according to a new study published http://www.cmaj.ca/site/press/cmaj.161082.pdf in CMAJ.

27 Feb 2017

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections in Seattle, a leading annual conference of HIV research, clinical practice and progress.

24 Feb 2017

New research pinpoints how immigrant microbes get to the lungs

They traveled a huge distance, evaded a protective barrier, and found themselves in a strange and unwelcoming land.

23 Feb 2017

Estrogen therapy can lead to healthier teeth and gums in postmenopausal women, study suggests

Estrogen therapy has already been credited with helping women manage an array of menopause-related issues, including reducing hot flashes, improving heart health and bone density, and maintaining levels of sexual satisfaction.

22 Feb 2017

Research shines new light on role of AKI in development of lung injury

Acute kidney injury (AKI) is sudden kidney failure or damage lasting from a few hours to several days. During this time, the kidney's ability to maintain a proper balance of bodily fluids is compromised and causes a buildup of waste products in the blood.

22 Feb 2017

Melanoma patients' immunotherapy response linked to diversity and makeup of gut bacteria

Melanoma patients' response to a major form of immunotherapy is associated with the diversity and makeup of trillions of potential allies and enemies found in the digestive tract, researchers at The University of Texas MD Anderson Cancer Center report at the ASCO-Society for Immunotherapy in Cancer meeting in Orlando.

22 Feb 2017

Novel substance can effectively inhibit chronic nerve pain, study shows

Trigeminal neuralgia is characterized by sharp, lancinating pain in the teeth or facial area. The standard treatment for this chronic nerve pain can cause burdening side effects.

20 Feb 2017

Oral News and Research

Combined therapy extends survival of older patients with glioblastoma, clinical study shows

Children with mild eczema unlikely to benefit from antibiotics, study shows

Case studies for the role of in-process particle measurement to complement traditional API dissolution studies

New approach shows promise to prevent, treat cholesterol gallstone disease

Mite-proof covers may reduce severity of asthma exacerbations in allergic children

Dental plaque DNA of Neandertals provides insights into behaviour, diet and medication

Researchers develop skin tests, decision support tool to increase antibiotic use in hospitalized patients

EuroPrevent 2017 to explore innovative ideas in preventive cardiology

Study finds link between vitamin D levels and severity of malabsorption issues

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Tailored preventive oral health intervention improves cleanliness of teeth, dentures among older adults

Researchers develop nerve wrapping nanofiber mesh to facilitate regeneration, restore function

Early preventive dental care for Medicaid-enrolled children may lead to long-term treatment, study suggests

Universal public coverage of essential medicines could save over $4 billion per year, study finds

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

New research pinpoints how immigrant microbes get to the lungs

Estrogen therapy can lead to healthier teeth and gums in postmenopausal women, study suggests

Research shines new light on role of AKI in development of lung injury

Melanoma patients' immunotherapy response linked to diversity and makeup of gut bacteria

Novel substance can effectively inhibit chronic nerve pain, study shows

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