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Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

A recent European Urology Oncology study assessed the mortality risks, based on the Gleason score and clinical parameters, in patients with prostate cancer.

11 Jul 2024

The effect of supplementation with cornelian cherry on different cardiometabolic outcomes

A recent meta-analysis in Nutrients examined recent studies on the cornelian cherry, Cornus mas L., for evidence of its cardiometabolic benefit.

11 Jul 2024

Researchers identify shared molecular mechanism in cancer and pregnancy that suppresses immune system

Researchers elucidated the shared immune tolerance mechanisms in cancer and pregnancy, focusing on the role of an immune checkpoint protein as an onco-fetal immune tolerance checkpoint.

11 Jul 2024

Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

New gene editing technique offers hope for millions

A team led by Mass Eye and Ear researchers has demonstrated for the first time a successful restoration of hearing through a novel, in vivo genome editing approach in an adult mouse model with a form of inherited deafness caused by mutations in microRNA.

11 Jul 2024

Scientists discover a molecular defect that promotes pathologic immune response in lupus

Northwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect may potentially reverse the disease.

10 Jul 2024

Novel molecule could inform new therapies for stroke-related brain injury

A newly developed molecule, LK-2, could inform new therapies for stroke-related brain injury, finds scientists at The Hospital for Sick Children (SickKids).

10 Jul 2024

New consortium receives NIH grant to accelerate development of effective TB treatments

A new consortium co-led by Weill Cornell Medicine, has been awarded a five-year, $31 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis (TB).

10 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

Researchers performed saturation genome editing of the BAP1, whose dysfunction is related to cancer and impaired neurodevelopment.

10 Jul 2024

Tirzepatide outperforms semaglutide in weight loss for overweight and obese adults

Tirzepatide leads to significantly greater weight loss than semaglutide in overweight or obese adults, with no significant difference in gastrointestinal adverse effects.

10 Jul 2024

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Researchers trace the 60-year evolution of lipid nanoparticles (LNPs) for nucleic acid delivery, highlighting their potential to revolutionize gene therapy with safer and more effective treatments.

10 Jul 2024

New guidelines can help alleviate unnecessary referrals related to unexpected bleeding

The British Menopause Society (BMS) has launched new, joint guidelines for GPs to help alleviate unnecessary referrals related to unexpected bleeding.

10 Jul 2024

Targeted alpha therapy offers hope for glioblastoma patients

A new approach to treating the most malignant type of brain cancer – glioblastoma – has shown strong promise in pre-clinical settings, raising hopes of increasing current average survival rates beyond 18 months.

10 Jul 2024

Fungal endophytes: A promising frontier for breast cancer treatment

A recent study in Heliyon highlights the potential of fungal endophytes in developing novel anti-cancer agents, specifically targeting breast cancer therapy.

10 Jul 2024

Mayo Clinic makes medical history with total larynx transplant for cancer patient

Mayo Clinic announces a groundbreaking achievement in organ transplantation, offering hope to thousands who have lost their ability to speak, swallow and breathe on their own due to diminished function or loss of their larynx.

9 Jul 2024

Stem-like cells found to drive growth of aggressive pediatric brain tumors

A team of researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions has identified and located a population of stem-like cells that initiates and maintains Group 3 medulloblastoma (Gr3-MB) in the developing brain.

9 Jul 2024

Transforming growth factor beta inhibition boosts NK cell therapy against hepatocellular carcinoma

Researchers at University of California San Diego have found that the most common form of liver cancer - one with a high mortality rate - can be better targeted and treated using an innovative new stem cell-derived therapy, according to a recently published study in Cell Stem Cell.

9 Jul 2024

Study finds increased risk of lumbar spinal fusion failure in diabetic patients

A new study from orthopedic researchers at The University of Toledo has found lumbar spinal fusion procedures are far more likely to fail in individuals with diabetes.

9 Jul 2024

Study uncovers a potential treatment for food allergies in a naturally occurring plant fiber

A study from the University of Michigan has identified a potential new treatment for food allergies in inulin, a naturally occurring plant fiber commonly used as a supplement, a prebiotic in soda, a replacement for sweeteners and for other products and purposes.

9 Jul 2024

Therapy News and Research

Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

The effect of supplementation with cornelian cherry on different cardiometabolic outcomes

Researchers identify shared molecular mechanism in cancer and pregnancy that suppresses immune system

Existing drug shows promise for treating common liver disease

New gene editing technique offers hope for millions

Scientists discover a molecular defect that promotes pathologic immune response in lupus

Novel molecule could inform new therapies for stroke-related brain injury

New consortium receives NIH grant to accelerate development of effective TB treatments

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

Tirzepatide outperforms semaglutide in weight loss for overweight and obese adults

60 years in the making: Nanoparticles revolutionize nucleotide delivery

New guidelines can help alleviate unnecessary referrals related to unexpected bleeding

Targeted alpha therapy offers hope for glioblastoma patients

Fungal endophytes: A promising frontier for breast cancer treatment

Mayo Clinic makes medical history with total larynx transplant for cancer patient

Stem-like cells found to drive growth of aggressive pediatric brain tumors

Transforming growth factor beta inhibition boosts NK cell therapy against hepatocellular carcinoma

Study finds increased risk of lumbar spinal fusion failure in diabetic patients

Study uncovers a potential treatment for food allergies in a naturally occurring plant fiber

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