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Machine learning reveals sleep quality and anxiety as major predictors of depression

Researchers applied machine learning to predict depressive symptoms, revealing sleep quality and anxiety as key factors across diverse populations and datasets.

12 Sep 2024

Researchers uncover why typically normal protein drives prostate cancer

NSD-2 is crucial for AR activity in prostate cancer, promoting tumor growth and offering a potential therapeutic target for advanced prostate cancer treatment.

12 Sep 2024

Laughter exercise could be an initial treatment for relieving dry eye disease symptoms

Laughter may be as effective as eye drops in improving symptoms of dry eye disease, finds a clinical trial from China published by The BMJ today.

11 Sep 2024

Long radiotherapy course shows better organ preservation in rectal cancer

The COVID-19 pandemic has enabled researchers to show that a long course of radiotherapy given before surgery may be a better treatment for avoiding surgery, preserving the rectum and anus, and preventing regrowth of the primary tumor than a short course of radiotherapy for patients with rectal cancer – a type of bowel cancer.

11 Sep 2024

Telisotuzumab vedotin shows promising results in asian patients with c-Met overexpressing NSCLC

The c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an acceptable safety profile in patients of Asian race with c-Met protein-overexpressing, epidermal growth factor receptor (EGFR) wildtype (WT), locally advanced/metastatic nonsquamous non-small cell lung cancer (NSCLC), according to research presented today at the International Association for the Study of Lung Cancer's 2024 World Conference on Lung Cancer.

11 Sep 2024

Study shows CAR T-cell therapy's risk of second primary malignancies comparable to other treatments

The frequency of second primary malignancies (SPMs) arising in cancer survivors following treatment with CAR T-cell therapy was statistically comparable to the frequency of SPMs following other standard-of-care therapies, according to a systematic review and meta-analysis.

11 Sep 2024

Zongertinib shows promising efficacy in HER2 mutation-positive NSCLC

The HER2-specific tyrosine kinase inhibitor zongertinib was well tolerated and demonstrated promising efficacy in patients with HER2 mutation-positive non-small cell lung cancer, meeting the primary endpoint of the Beamion LUNG-1 Phase Ib Cohort 1 study, according to research presented today at the International Association for the Study of Lung Cancer 2024 World Conference on Lung Cancer.

11 Sep 2024

Pre-surgery chemotherapy shows promise for preserving vital organs in nasal and sinus cancer

Results from a clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) show a striking improvement for patients who received chemotherapy before surgery to remove advanced squamous cell-type cancer of the nose or sinus.

11 Sep 2024

World champion marathon runner’s life study highlights benefits and risks of life-long endurance exercise

Decades of intense marathon training have preserved heart function in a 77-year-old, highlighting benefits and risks of extreme endurance exercise.

11 Sep 2024

New study links gut bacteria to thiamine's role in reducing fatigue in IBD patients

Researchers explore the frequency of symptoms like chronic fatigue in IBD in relation to specific bacteria in the human gut.

11 Sep 2024

New study explores the potential of hormone therapy for opioid recovery

In the midst of America's growing opioid crisis, a much healthier alternative to long-term pain management is emerging - one affectionately known as "the cuddle hormone," or oxytocin.

11 Sep 2024

Addressing the challenges of polycystic kidney disease

Polycystic kidney disease (PKD) is an intractable disorder that causes fluid-filled cysts to grow in the kidneys. It is typically seen in adults. As one of the most prevalent hereditary kidney diseases, the autosomal dominant form of PKD is usually caused by mutations in the PKD1 and PKD2 genes.

11 Sep 2024

Promising new approach to combat HIV

Researchers at Université de Montréal's affiliated hospital research center, the CRCHUM, say the discovery could help lessen and even eliminate viral loads in people undergoing antiretroviral therapy.

11 Sep 2024

New guidelines for the evaluation and management of chronic constipation

The American Society of Colon and Rectal Surgeons (ASCRS) has issued updated guidelines, published in Diseases of the Colon & Rectum, about how to evaluate and manage chronic constipation. The journal is published in the Lippincott portfolio by Wolters Kluwer.

11 Sep 2024

Fibrous scars drive glioblastoma recurrence

A Ludwig Cancer Research study has discovered that recurrent tumors of the aggressive brain cancer glioblastoma multiforme (GBM) grow out of the fibrous scars of malignant predecessors destroyed by interventions such as radiotherapy, surgery, and immunotherapy.

11 Sep 2024

Air pollution spikes drive unnecessary antibiotic use, fueling resistance

Short-term exposure to air pollution significantly increases antimicrobial use for acute respiratory symptoms, highlighting a potential contributor to antibiotic resistance.

10 Sep 2024

Study highlights barriers to discussing therapeutic psychedelics with physicians

Feeling safe and comfortable are key when discussing your health and wellbeing with your primary care provider.

10 Sep 2024

Statins found to be cost-effective and linked to better health outcomes in older adults

Statin treatment is cost-effective and linked to better health outcomes in older people with or without previous cardiovascular disease, although the risk reductions were substantially smaller in the latter, reports a modeling on the lifetime benefits of these drugs among the over-70s, published online in the journal Heart.

10 Sep 2024

Obesity medication liraglutide safe and effective in children under 12, research finds

The obesity medication liraglutide is safe and effective in children aged 6 to <12 years, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September), and published simultaneously in the New England Journal of Medicine (NEJM), has found.

10 Sep 2024

Gene therapy improves vision in patients with Bothnia dystrophy

Bothnia dystrophy is a form of hereditary blindness, prevalent in the region Västerbotten in Sweden. A new study at Karolinska Institutet published in Nature Communications shows that gene therapy can improve vision in patients with the disease.

10 Sep 2024

Therapy News and Research

Machine learning reveals sleep quality and anxiety as major predictors of depression

Researchers uncover why typically normal protein drives prostate cancer

Laughter exercise could be an initial treatment for relieving dry eye disease symptoms

Long radiotherapy course shows better organ preservation in rectal cancer

Telisotuzumab vedotin shows promising results in asian patients with c-Met overexpressing NSCLC

Study shows CAR T-cell therapy's risk of second primary malignancies comparable to other treatments

Zongertinib shows promising efficacy in HER2 mutation-positive NSCLC

Pre-surgery chemotherapy shows promise for preserving vital organs in nasal and sinus cancer

World champion marathon runner’s life study highlights benefits and risks of life-long endurance exercise

New study links gut bacteria to thiamine's role in reducing fatigue in IBD patients

New study explores the potential of hormone therapy for opioid recovery

Addressing the challenges of polycystic kidney disease

Promising new approach to combat HIV

New guidelines for the evaluation and management of chronic constipation

Fibrous scars drive glioblastoma recurrence

Air pollution spikes drive unnecessary antibiotic use, fueling resistance

Study highlights barriers to discussing therapeutic psychedelics with physicians

Statins found to be cost-effective and linked to better health outcomes in older adults

Obesity medication liraglutide safe and effective in children under 12, research finds

Gene therapy improves vision in patients with Bothnia dystrophy

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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