Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Calorie restriction not the only way to increase longevity

New research carried out by University College London (UCL) scientists has found that it is possible to increase life expectancy by 50% without decreasing calorie intake - at least in fruitflies.

3 Jun 2005

Gene research may help explain how adorable children become surly teenagers

University of Utah researchers showed that a fruit fly gene is crucial for determining when juveniles begin to mature into adults, and how the transformation initially proceeds. Understanding this process in humans may help explain how adorable children become surly teenagers.

3 Jun 2005

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

In the latest version of the hide-and-seek game between pathogens and the hosts they infect, researchers have found that a virus appears to cloak itself with a recently discovered gene silencing device to evade detection and destruction by immune cells.

3 Jun 2005

Novel insights into how prion and other neurodegenerative diseases develop

Abnormal prion proteins are little understood disease agents involved in causing horrific brain-wasting diseases such as Creutzfeldt-Jacob disease in people, mad cow disease in cattle and chronic wasting disease in deer and elk.

3 Jun 2005

Research explains why Shigella and E. coli are rapidly becoming resistant to fluoroquinolones

Scientists at the Albert Einstein College of Medicine have discovered a novel strategy by which the bacterium that causes tuberculosis may soon be able to resist the effects of antibiotics known as fluoroquinolones.

3 Jun 2005

New vaccine against whooping cough is effective in teens and adults

The Journal of the American Medical Association (JAMA) has announced that a study to be published in the June 22/29 issue found that a new vaccine against whooping cough is effective in teens and adults, carriers of the contagious respiratory disease so dangerous to infants.

3 Jun 2005

A protein found naturally in the brain may protect against Parkinson's disease

The findings also may lead to an improved understanding of a disorder called early-onset torsion dystonia.

2 Jun 2005

Novel strategy proves highly effective in killing drug-resistant multiple myeloma cells

A novel strategy devised by Dana-Farber Cancer Institute scientists has proved highly effective in killing drug-resistant multiple myeloma cells in the laboratory and could open a new form of attack on the deadly blood cancer, they report.

2 Jun 2005

Scientists have uncovered the structure of a network of proteins that help regulate the life cycle of cells

Scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) have uncovered the structure of a network of proteins that help regulate the life cycle of cells. Understanding the network's physical layout is an important step toward learning its precise function, and in finding ways to correct flaws in the system that could lead to cancer.

2 Jun 2005

The bacteria that cause food poisoning, bubonic plague, and whooping cough all deploy the same weapon to infect the body

A molecular "syringe" sticks out of the bacteria, pokes a hole in a nearby cell, and squirts in venomous proteins that hijack the cell's machinery.

2 Jun 2005

Study links TNF to androgen deficiency in rheumatoid arthritis patients and suggest a novel pathway in inflammation

A protein involved in multiple cell functions, tumor necrosis factor (TNF) is perhaps best known for provoking destructive inflammation. Recently, drugs blocking the action of TNF have shown promise in the early treatment of rheumatoid arthritis (RA).

2 Jun 2005

Genetic variation alters response to anti-clotting drug warfarin

Millions of people take the anticoagulant drug warfarin to prevent harmful clotting after a heart attack, stroke, or major surgery. But the proper dose of warfarin can vary greatly and can be hard to predict.

1 Jun 2005

Scientists shed new light on how protein Ro creates RNA quality control system for cells

A report by Yale scientists in the journal Cell sheds new light on how the protein Ro, a major autoantigen in patients with autoimmune disease, recognizes misfolded RNAs, creating a RNA quality control system for cells.

1 Jun 2005

New clue to understanding how fatty acids work in the brain

Scientists in Cambridge have discovered that a brain protein called syntaxin enables fatty molecules, used widely in health supplements, to work in the brain to make it function properly. Lead Scientist, Dr Bazbek Davletov and his colleague Dr Colin Rickman from the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, UK report their findings in the journal Chemistry and Biology.

1 Jun 2005

Diagnostic test for Lou Gehrig's disease

Bowser is director of the ALS Tissue Bank and an Associate Professor of Pathology at the University of Pittsburgh School of Medicine who is using a key piece of biomarker discovery equipment known as SELDI to find new ways to identify and eventually treat Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease.

1 Jun 2005

Lafora disease can be caused by mutations in a gene that regulates the concentration of the protein laforin

Researchers at University of California, San Diego (UCSD) have found that Lafora disease, an inherited form of epilepsy that results in death by the age of 30, can be caused by mutations in a gene that regulates the concentration of the protein laforin. These findings are reported in the current issue of Proceedings of the National Academy of Sciences (PNAS).

1 Jun 2005

Triple approach is promising against cancer cells

A trimodal treatment strategy combining chemotherapy, radiation therapy, and a protein kinase inhibitor is much more effective against cancer cells than any combination of only two treatment methods.

1 Jun 2005

Interaction between cell and virus provides scientists valuable insights into the development of safe viral vectors for use in oncology

When infected by a virus, a cell uses specific defense mechanisms developed in the course of a long evolution. Thus, it can activate enzymes that disrupt or prevent replication of the viruses within the cell.

1 Jun 2005

New approach to inhibiting blood vessel growth or angiogenesis

A manmade protein with a tail of amino acids delivered to target cells can dramatically reduce blood vessel growth that obstructs vision or feeds a tumor, researchers have found.

31 May 2005

New gene shows way for autoimmune disease

A new gene suspected to contribute to autoimmune diseases such as type 1 diabetes and lupus - a condition in which the body’s own immune system attacks organs such as the kidneys and skin - has been discovered by Australian National University (ANU) immunologists.

30 May 2005

Protein News and Research

Further Reading

Calorie restriction not the only way to increase longevity

Gene research may help explain how adorable children become surly teenagers

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

Novel insights into how prion and other neurodegenerative diseases develop

Research explains why Shigella and E. coli are rapidly becoming resistant to fluoroquinolones

New vaccine against whooping cough is effective in teens and adults

A protein found naturally in the brain may protect against Parkinson's disease

Novel strategy proves highly effective in killing drug-resistant multiple myeloma cells

Scientists have uncovered the structure of a network of proteins that help regulate the life cycle of cells

The bacteria that cause food poisoning, bubonic plague, and whooping cough all deploy the same weapon to infect the body

Study links TNF to androgen deficiency in rheumatoid arthritis patients and suggest a novel pathway in inflammation

Genetic variation alters response to anti-clotting drug warfarin

Scientists shed new light on how protein Ro creates RNA quality control system for cells

New clue to understanding how fatty acids work in the brain

Diagnostic test for Lou Gehrig's disease

Lafora disease can be caused by mutations in a gene that regulates the concentration of the protein laforin

Triple approach is promising against cancer cells

Interaction between cell and virus provides scientists valuable insights into the development of safe viral vectors for use in oncology

New approach to inhibiting blood vessel growth or angiogenesis

New gene shows way for autoimmune disease

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