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Discovery of vital key to cancer

University of Manchester scientists have uncovered the 3D structure of Mps1 - a protein that regulates the number of chromosomes during cell division and thus has an essential role in the prevention of cancer - which will lead to the design of safer and more effective therapies.

From The University of Manchester 6 Aug 2008

Genetic biomarker linked to subcutaneous growth hormone dose-response

The interindividual variability of response to subcutaneously applied protein-based drugs remains poorly understood. However, defining genetic markers that can be associated with biological effects of such drugs may improve the understanding of individual variability of response and even drug resistance.

6 Aug 2008

Highly active antiretroviral therapy (HAART) equally effective in patients with or without history of injection drug use

Highly active antiretroviral therapy (HAART) has been extremely effective at slowing the progression of HIV infection to AIDS as well as extending the lives and improving the quality of life for those with HIV. However, some doctors have been reluctant to prescribe HAART to HIV-infected injection drug users because of concern that they may not fully benefit from the therapy.

6 Aug 2008

600,000 Australians afflicted with osteoporosis

According to a new report by the Australian Institute of Health and Welfare (AIHW) and Osteoporosis Australia, more than 600,000 Australians are affected by osteoporosis.

5 Aug 2008

Revolutionary technique that could reduce lifelong drugs for transplant patients shows promising findings

Researchers have developed a ground-breaking procedure that could avoid the need for transplant patients to spend the rest of their lives taking a cocktail of drugs to stop their system from rejecting their new organ, according to a series of papers in the August issue of Transplant International.

5 Aug 2008

YMCA and Fred Hutchinson Cancer Research Center offer free exercise program for cancer survivors

Puget Sound-area cancer survivors have access to a new strength-and-fitness program designed specifically for them thanks to a partnership between the YMCA of Greater Seattle and Fred Hutchinson Cancer Research Center.

4 Aug 2008

Oestrogen - a beneficial addition to treatment of schizophrenia in women

Australian scientists have found that women suffering from schizophrenia were less likely to suffer hallucinations or delusions, when the hormone oestrogen was added to their treatment.

4 Aug 2008

Bionor Immuno trials new innovative therapeutic immunization designed to help existing HIV and AIDS patients

Bionor Immuno today announced that it has advanced its efforts to develop the first HIV therapeutic immunization with the dosing of patients in a global Phase 2b clinical trial of the company's lead candidate (Vacc-4x).

4 Aug 2008

Vitamin C injections slow tumor growth in mice

High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences.

4 Aug 2008

Targeted action on HIV and tuberculosis needed to reach drug users

Health and criminal justice authorities need to provide targeted services to drug users, especially those who inject drugs, to prevent and treat tuberculosis (TB) and HIV. TB is a major cause of death for people living with HIV, but drug users who are HIV-positive face stigma, discrimination and barriers to accessing life-saving treatments.

4 Aug 2008

Many cancer patients found to be using complementary and alternative methods

A new study from researchers at the American Cancer Society finds many cancer patients use complementary and alternative methods, most often prayer, relaxation, supplements, meditation, and massage. Meanwhile, the use of other methods, such as biofeedback, homeopathy, and acupressure, are relatively uncommon.

4 Aug 2008

Epilepsy drug gabapentin may reduce insomnia in recovering alcoholics

It's a Catch-22 of the highest order. People with alcohol problems often use alcohol to get to sleep -- but it actually keeps them from getting good-quality sleep all night long.

4 Aug 2008

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer

CB1 is well-established for relieving pain and nausea, elevating mood and stimulating appetite by serving as a docking station for the cannabinoid group of signaling molecules. It now may serve as a new path for cancer prevention or treatment.

3 Aug 2008

Chronic exposure to estrogen impairs some cognitive functions

University of Illinois researchers report this week that chronic exposure to estradiol, the main estrogen in the body, diminishes some cognitive functions. Rats exposed to a steady dose of estradiol were impaired on tasks involving working memory and response inhibition, the researchers found.

3 Aug 2008

Methadone shows promise against leukemia

Researchers in Germany have discovered that methadone, an agent used to break addiction to opioid drugs, has surprising killing power against leukemia cells, including treatment resistant forms of the cancer.

3 Aug 2008

Disparities in prostate cancer treatment suggest ways to improve care

Quality of care varies greatly for the treatment of men with early-stage prostate cancer by region of the country and category of health care facility, suggesting the potential for improved patient outcomes with more standard treatment protocols, according to a new study that was published in the Aug. 1 issue of the Journal of Clinical Oncology (2008: Vol. 26, Issue 22).

3 Aug 2008

Immunotherapy shows promise in high-risk pediatric sarcomas

Based on a pilot study in children with sarcoma, researchers at the National Institutes of Health (NIH) believe that immunotherapy could prove beneficial in treating high-risk forms of this cancer.

3 Aug 2008

Certain HIV treatment less effective when used with rifampicin-based anti-tuberculosis therapy

Patients receiving rifampicin-based anti-tuberculosis therapy are more likely to experience virological failure when starting nevirapine-based antiretroviral therapy, an HIV treatment that is widely used in developing countries because of lower cost, than when starting efavirenz-based antiretroviral therapy, according to a study in the August 6 issue of JAMA, a theme issue on HIV/AIDS.

3 Aug 2008

Growth hormone reduces abdominal fat, cardiovascular risk in HIV patients on antiviral therapy

Low-dose growth hormone treatment reduced abdominal fat deposits and improved blood pressure and triglyceride levels in a group of patients with HIV lipodystrophy, a condition involving the redistribution of fat and other metabolic changes in patients receiving combination drug therapy for HIV infection.

3 Aug 2008

Update of treatment guidelines for HIV infection recommended by experts

An evaluation of the latest information on the treatment of the adult human immunodeficiency virus (HIV) has led an international panel of experts to update the guidelines and recommendations for antiretroviral treatment of HIV.

3 Aug 2008

Therapy News and Research

Discovery of vital key to cancer

Genetic biomarker linked to subcutaneous growth hormone dose-response

Highly active antiretroviral therapy (HAART) equally effective in patients with or without history of injection drug use

600,000 Australians afflicted with osteoporosis

Revolutionary technique that could reduce lifelong drugs for transplant patients shows promising findings

YMCA and Fred Hutchinson Cancer Research Center offer free exercise program for cancer survivors

Oestrogen - a beneficial addition to treatment of schizophrenia in women

Bionor Immuno trials new innovative therapeutic immunization designed to help existing HIV and AIDS patients

Vitamin C injections slow tumor growth in mice

Targeted action on HIV and tuberculosis needed to reach drug users

Many cancer patients found to be using complementary and alternative methods

Epilepsy drug gabapentin may reduce insomnia in recovering alcoholics

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer

Chronic exposure to estrogen impairs some cognitive functions

Methadone shows promise against leukemia

Disparities in prostate cancer treatment suggest ways to improve care

Immunotherapy shows promise in high-risk pediatric sarcomas

Certain HIV treatment less effective when used with rifampicin-based anti-tuberculosis therapy

Growth hormone reduces abdominal fat, cardiovascular risk in HIV patients on antiviral therapy

Update of treatment guidelines for HIV infection recommended by experts

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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