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High blood pressure associated with reduced mortality in extremely frail, elderly adults

A new study suggests that higher blood pressure is associated with lower mortality in extremely frail, elderly adults.

17 Jul 2012

Researchers begin to uncover important clues about SCAD

Spontaneous coronary artery dissection (SCAD), a tear of the layers of the artery wall that can block normal blood flow into and around the heart, is a relatively rare and poorly understood condition. It often strikes young, otherwise healthy people -- mostly women -- and can lead to significant heart damage, even sudden death.

17 Jul 2012

New Alzheimer's model derived from skin cells of patients may prove to be more accurate

Researchers at the Alzheimer's Association International Conference 2012 (AAIC 2012) today reported the creation of a new model of Alzheimer's derived from the skin cells of people with the disease that were reprogramed into Alzheimer's brain cells.

17 Jul 2012

Helper T cells may be frontline warriors when battling hepatitis A infection

Helper cells traditionally thought to only assist killer white blood cells may be the frontline warriors when battling hepatitis A infection. These are the findings from a Nationwide Children's Hospital study appearing in a recent issue of the Journal of Experimental Medicine.

17 Jul 2012

Tips to help minimize risks associated with acid reflux disease

While the overall death rates from several cancers such as breast and lung have gone down, there has been a meteoric rise in cases of esophageal cancer. Studies have shown that from 1975 to 2001, the incidence of esophageal adenocarcinoma rose approximately sixfold in the United States (from four to 23 cases per million), a relative increase greater than that for melanoma, breast, or prostate cancer.

17 Jul 2012

Why is the incidence of gout increasing?

Gout has been described by the Daily Mail as something, “usually associated with port-swilling, over-fed elderly men of the 19th century”. (1) Recent research carried out at the Boston University School of Medicine, however, has found that the incidence of gout in the US is on the rise. (2) Thus, the condition is clearly not something that only affects this stereotype.

17 Jul 2012

Scientists discover new way to convert cord blood cells into iNC

For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, from cancer and immune disorders to blood and metabolic diseases.

17 Jul 2012

VHVI now offers new minimally invasive, catheter-based approach to dissolve pulmonary embolism

The Vanderbilt Heart and Vascular Institute (VHVI) now offers a minimally invasive, catheter-based approach to dissolving pulmonary embolism, a potentially life-threatening blood clot that form elsewhere in the body and travels into the lungs.

17 Jul 2012

BRAF L597 mutation in melanoma patients responds to MEK inhibitor drugs

An uncommon mutation of the BRAF gene in melanoma patients has been found to respond to MEK inhibitor drugs, providing a rationale for routine screening and therapy in melanoma patients who harbor the BRAF L597 mutation.

17 Jul 2012

InvivoSciences, WUSTL to construct artificial tissue models for heart failure

The National Institutes of Health has awarded more than $2 million to a team of scientists from Washington University in St. Louis and InvivoSciences, a biotechnology startup with WUSTL roots, to construct artificial tissue models that will allow the rapid testing of new drugs for heart failure.

17 Jul 2012

Targeting CDK1 pathway may be efficacious for acute myeloid leukemias with FLT3 mutation

Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are among the most prevalent mutations observed in acute myeloid leukemias. FLT3 mutants are thought to activate several signaling pathways that contribute to cancer development.

17 Jul 2012

Abbott to showcase new informatics and lab solutions at AACC annual meeting

Abbott will feature new solutions to improve data management and automation at this year's American Association for Clinical Chemistry (AACC) annual meeting, July 15-19, in Los Angeles, Calif. Solutions to further enhance efficiency and workflow in today's laboratories will be the focal point of the Abbott exhibit.

16 Jul 2012

St. Joseph Hospital initiates enrollment in Medtronic’s SYMPLICITY HTN-3 trial for hypertension

St. Joseph Hospital of Orange on July 11 enrolled its first patient as part of a national clinical trial conducted by Medtronic Inc. for a renal denervation procedure designed to eliminate treatment-resistant hypertension.

From Medtronic 16 Jul 2012

Studies describe ability of targeted exercise training on cognitive impairment and dementia

Four studies reported today at the Alzheimer's Association International Conference 2012 (AAIC 2012) describe the ability of targeted exercise training to promote improved mental functioning and reduced risk for cognitive impairment and dementia in cognitively healthy older adults and those with mild cognitive impairment (MCI).

16 Jul 2012

IDH mutation drives aggressive form of acute myeloid leukemia

Many patients with acute myeloid leukemia (AML) share a mutation in a gene called IDH. A University of Colorado Cancer Center study published this week in the journal Leukemia & Lymphoma shows that this IDH mutation may be the first domino in a chain that leads to a more aggressive form of the disease.

16 Jul 2012

Scientists uncover new strategy that may help reverse mucus dehydration in CF, COPD

University of North Carolina scientists have uncovered a new strategy that may one day help people with cystic fibrosis and chronic obstructive pulmonary disorder better clear the thick and sticky mucus that clogs their lungs and leads to life-threatening infections.

16 Jul 2012

Cleveland Clinic receives NHLBI grant to identify new pathways linked with cardiovascular diseases

The National Heart, Lung, and Blood Institute (NHLBI) has awarded a $4.78 million grant to researchers at Cleveland Clinic's Lerner Research Institute to use metabolomics - a new approach that focuses on the small-molecule byproducts of metabolism - for discovery of novel pathways linked to the development of cardiovascular diseases.

14 Jul 2012

New noninvasive imaging technique may help detect heart transplant rejection in children

Cardiologists at Washington University School of Medicine in St. Louis have developed a noninvasive imaging technique that may help determine whether children who have had heart transplants are showing early signs of rejection. The technique could reduce the need for these patients to undergo invasive imaging tests every one to two years.

14 Jul 2012

Body rids itself of excess copper through urine: New study

Scientists have long known that the body rids itself of excess copper and various other minerals by collecting them in the liver and excreting them through the liver's bile. However, a new study led by Johns Hopkins researchers and published June 22 in PLoS One suggests that when this route is impaired there's another exit route just for copper: A molecule sequesters only that mineral and routes it from the body through urine.

14 Jul 2012

Health risks of egg donation for young females

News is just breaking in India about Sushma Pandey, a 17-year-old young woman who died in 2010, two days after her third "egg donation." Her death is being attributed to the procedures used to extract eggs from healthy, desirable young females like Ms. Pandey. These eggs are often resold to affluent westerners for use in commercial production of their children. Her post-mortem report states she had "one abrasion, four contusions and a blood clot in the head, plus six injection marks" as well as "congestion in the ovaries and uterus."

14 Jul 2012

Blood News and Research

High blood pressure associated with reduced mortality in extremely frail, elderly adults

Researchers begin to uncover important clues about SCAD

New Alzheimer's model derived from skin cells of patients may prove to be more accurate

Helper T cells may be frontline warriors when battling hepatitis A infection

Tips to help minimize risks associated with acid reflux disease

Why is the incidence of gout increasing?

Scientists discover new way to convert cord blood cells into iNC

VHVI now offers new minimally invasive, catheter-based approach to dissolve pulmonary embolism

BRAF L597 mutation in melanoma patients responds to MEK inhibitor drugs

InvivoSciences, WUSTL to construct artificial tissue models for heart failure

Targeting CDK1 pathway may be efficacious for acute myeloid leukemias with FLT3 mutation

Abbott to showcase new informatics and lab solutions at AACC annual meeting

St. Joseph Hospital initiates enrollment in Medtronic’s SYMPLICITY HTN-3 trial for hypertension

Studies describe ability of targeted exercise training on cognitive impairment and dementia

IDH mutation drives aggressive form of acute myeloid leukemia

Scientists uncover new strategy that may help reverse mucus dehydration in CF, COPD

Cleveland Clinic receives NHLBI grant to identify new pathways linked with cardiovascular diseases

New noninvasive imaging technique may help detect heart transplant rejection in children

Body rids itself of excess copper through urine: New study

Health risks of egg donation for young females

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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