Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

FDA clears Soligenix's IND application for SGX942 for treatment of oral mucositis

Soligenix, Inc., a clinical stage biopharmaceutical company, announced today that the Food and Drug Administration has completed its review and cleared the Investigational New Drug application for SGX942 for the treatment of oral mucositis resulting from radiation and/or chemotherapy treatment in head and neck cancer patients.

27 Mar 2013

Biological scientists lead major research project that aims to make drugs more effective

University of Southampton biological scientists are leading a major research project aimed at making drugs more effective.

27 Mar 2013

Viewpoints: Rising cost of Tricare; GOP needs to better explain Medicare eligibility age issue; Don't forget adult immunizations

The U.S. government's fiscal predicament has many causes. But if you had to reduce them to one sentence, it might go like this: "Congress responds to the short-term demands of particular groups, not the long-term needs of the nation as a whole."

27 Mar 2013

Study shows benefit of azithromycin in patients with non-CF bronchiectasis

Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to a study appearing in the March 27 issue of JAMA.

27 Mar 2013

Erythromycin may provide benefit for patients with non-CF bronchiectasis

Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic erythromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to a study appearing in the March 27 issue of JAMA.

27 Mar 2013

Presence of certain bacteria in stomach microbiota can prevent pathology from H. pylori

Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a study published online ahead of print in the journal Infection and Immunity.

26 Mar 2013

Organism may cause people to reap more calories from food, contributing to weight gain

How much a person eats may be only one of many factors that determines weight gain. A recent Cedars-Sinai study suggests that a breath test profile of microorganisms inhabiting the gut may be able to tell doctors how susceptible a person is to developing obesity.

26 Mar 2013

Genome sequencing reveals drug-resistant bacteria are transmitted from animals to humans

Researchers have used whole genome sequencing to reveal if drug-resistant bacteria are transmitted from animals to humans in two disease outbreaks that occurred on different farms in Denmark.

26 Mar 2013

TOBI Podhaler receives FDA approval for cystic fibrosis patients with Pseudomonas aeruginosa

The U.S. Food and Drug Administration today approved TOBI Podhaler (tobramycin inhalation powder) for the management of cystic fibrosis patients with Pseudomonas aeruginosa, a bacterium that causes lung infections.

24 Mar 2013

Positive results from Affinium Pharmaceuticals' Phase 2a clinical trial of AFN-1252 in ABSSSI

Affinium Pharmaceuticals announced today that its Phase 2a clinical trial evaluating oral AFN-1252 in acute bacterial skin & skin structure infections demonstrated excellent efficacy and safety data, marking a significant proof-of-concept milestone for Affinium's first-in-class, novel antibiotic targeted against bacterial fatty acid biosynthesis inhibition (FabI inhibitors).

21 Mar 2013

TSRI receives fund to develop new field test for Onchocerciasis

Philanthropist, businessman and community leader John Moores has given The Scripps Research Institute approximately $2 million to fund the development of a new field test for Onchocerciasis, or river blindness, a parasitic infection that affects tens of millions of people in Africa, Latin America and other tropical regions.

21 Mar 2013

Hepatitis C and HIV co-infection treatment: an interview with Prof Boecher, Boehringer Ingelheim

Chronic hepatitis C infection is one of the most frequent chronic infectious diseases worldwide. The WHO estimates that 150 million people worldwide are chronically infected with the hepatitis C virus (HCV).

20 Mar 2013

Viewpoints: Protect the FDA's regulatory efforts; Generic drug 'shenanigans;' Does Ryan not understand the 2012 election?

On Tuesday, the Supreme Court will hear arguments in Mutual Pharmaceutical v. Bartlett, a case about the ability of consumers to bring lawsuits against the makers of generic drugs.

20 Mar 2013

Research provides better understanding of microbiological factors of periodontitis

Microbes from the human mouth are telling Oak Ridge National Laboratory scientists something about periodontitis and more after they cracked the genetic code of bacteria linked to the condition.

19 Mar 2013

MRSA bacteria will continue to exist in both community and hospital settings

The drug-resistant bacteria known as MRSA, once confined to hospitals but now widespread in communities, will likely continue to exist in both settings as separate strains, according to a new study.

18 Mar 2013

Researchers receive AHRF grant to investigate genetic hearing screening program for newborns

Researchers at the Medical College of Wisconsin in Milwaukee, Wisconsin, have received a grant from the American Hearing Research Foundation to conduct a pilot study of genetic hearing screening for newborns at the Children's Hospital of Wisconsin to ensure the test can be performed and results shared with the parents in a timely and meaningful way.

15 Mar 2013

ST131 infection is more prevalent in LTCF residents and elderly population

Antibiotic-resistant Escherichia coli (E. coli) continues to proliferate, driven largely by expansion of a strain of E. coli know as sequence type ST131. A new study points to hospitals and long-term care facilities (LTCF) as settings in which this antibiotic-resistant strain is increasingly found.

14 Mar 2013

Dialysis patients face increased risk of antibiotic-resistant infections

Patients who receive hemodialysis are at a significant risk of developing infections, a leading cause of hospitalization and death in this patient population.

13 Mar 2013

Super gonorrhea spreads important health message to Parliament House

NPS MedicineWise launched its policy priorities in Canberra, spreading super gonorrhea toys around Parliament House to highlight the importance of fighting antibiotic resistance.

12 Mar 2013

Weight loss may help prevent and alleviate symptoms of osteoarthritis

Weight loss may prevent and significantly alleviate the symptoms of osteoarthritis, a progressive disease of the joints known as "wear and tear" arthritis, according to a literature review appearing in the March 2013 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS).

11 Mar 2013

Antibiotic News and Research

Further Reading

FDA clears Soligenix's IND application for SGX942 for treatment of oral mucositis

Biological scientists lead major research project that aims to make drugs more effective

Viewpoints: Rising cost of Tricare; GOP needs to better explain Medicare eligibility age issue; Don't forget adult immunizations

Study shows benefit of azithromycin in patients with non-CF bronchiectasis

Erythromycin may provide benefit for patients with non-CF bronchiectasis

Presence of certain bacteria in stomach microbiota can prevent pathology from H. pylori

Organism may cause people to reap more calories from food, contributing to weight gain

Genome sequencing reveals drug-resistant bacteria are transmitted from animals to humans

TOBI Podhaler receives FDA approval for cystic fibrosis patients with Pseudomonas aeruginosa

Positive results from Affinium Pharmaceuticals' Phase 2a clinical trial of AFN-1252 in ABSSSI

TSRI receives fund to develop new field test for Onchocerciasis

Hepatitis C and HIV co-infection treatment: an interview with Prof Boecher, Boehringer Ingelheim

Viewpoints: Protect the FDA's regulatory efforts; Generic drug 'shenanigans;' Does Ryan not understand the 2012 election?

Research provides better understanding of microbiological factors of periodontitis

MRSA bacteria will continue to exist in both community and hospital settings

Researchers receive AHRF grant to investigate genetic hearing screening program for newborns

ST131 infection is more prevalent in LTCF residents and elderly population

Dialysis patients face increased risk of antibiotic-resistant infections

Super gonorrhea spreads important health message to Parliament House

Weight loss may help prevent and alleviate symptoms of osteoarthritis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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