Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

SuperGen receives patent for composition and method for treating graft-versus-host disease

SuperGen has announced the issuance of U.S. Patent No. 7,037,900 B2 entitled, "Composition and Method for Treating Graft-versus-Host Disease."

5 Jun 2006

Finding opens new pathways for treating or preventing autoimmune diseases

A rare genetic defect that can trigger a host of diseases from type 1 diabetes to alopecia has helped explain the imbalance of immune regulator and killer cells in autoimmune disease.

31 May 2006

Research could lead to new treatments for idiopathic pulmonary fibrosis

Scientists at the University of Michigan Medical School have identified biochemical signals that attract pathogenic cells to damaged lung tissue - one of the first steps in a chain of events leading to a lethal disease called idiopathic pulmonary fibrosis or IPF.

23 May 2006

Adult survivors of childhood cancer and unemployment

Adults with a history childhood cancer are more likely than the general population to be unemployed, according to a new review.

23 May 2006

Study sheds light on cancer susceptibility and disease involving bone-marrow failure

Defective protein production can occur in cells even when the genes controlling those proteins are normal, according to a new study to be published May 12 in Science.

12 May 2006

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

10 May 2006

New treatment for chronic eosinophilic leukemia

Leukemia - or cancer of the bone marrow - strikes some 700 Belgians each year. Chronic Eosinophilic Leukemia (CEL), a specific form of leukemia, is currently treated with Glivec.

10 May 2006

Stem cell 'fusion' occurs in tumors

An Oregon Health & Science University study is adding credence to an increasingly popular theory that fusion is what bonds stem cells with bone marrow cells to regenerate organ tissue.

10 May 2006

Circulating tumor cells in the bone marrow of patients with metastatic renal cell carcinoma may be prognostic of outcome

Circulating tumor cells in the blood and bone marrow have been examined in a variety of malignancies, including colorectal, breast, and head & neck cancers, to determine their prognostic significance.

8 May 2006

Discovery of new type of cell that generates crucial immune system cells

A new type of cell that generates crucial cells of the immune system has been discovered at The Walter and Eliza Hall Institute.

8 May 2006

Differential effects of HOXB4 on nonhuman primate short and long-term repopulating cells

Transplantation of hematopoietic stem cells (HSCs, the cells that can give rise to all blood and most immune cell types) can save patients whose own hematopoietic system is defective or has been destroyed (often through radiation or chemotherapy of cancer).

3 May 2006

Protein produced by immune cells during malaria infection triggers severe anemia

Richard Bucala and colleagues at Yale University show that immune cells in mice with malaria secrete a protein called MIF, which decreases the production of red blood cells (RBCs) from the bone marrow. The study appears in The Journal of Experimental Medicine.

3 May 2006

Tumour specific drugs may render therapies based on a tumor's anatomical location obsolete

The results of a new study at Washington University School of Medicine in St. Louis could eventually have oncologists removing their specialties from their shingles by making therapy based on a tumor's anatomical location obsolete.

28 Apr 2006

Transplanted stem cells hoped to be able to regenerate damaged heart muscle in first heart attack victims

Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue.

28 Apr 2006

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

26 Apr 2006

Blood cancers may be caused by inactivation of a "tumor suppressor" gene

The discovery of a gene, called PRDM1, as a tumor suppressor sheds new light on the cause - and possible treatment - of diffuse large B-cell lymphomas (DLBCLs), a cancer of the blood's B-lymphocytes. DLBCLs comprise about 30 percent of non-Hodgkin's lymphomas.

25 Apr 2006

New method designed to analyze the genes that regulate the immune system

Seattle scientists have developed a new method for analyzing the Major Histocompatibility Complex (MHC) of the human genome.

20 Apr 2006

Discovery points to more effective ways of regulating cell signalling

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

20 Apr 2006

New finding provides researchers with renewable source for macrophages and neutrophils

A new approach to generating large quantities of two types of white blood cells that are critical for destroying invading bacteria, viruses and other pathogens in humans has been developed by researchers at the University of California, San Diego (UCSD) School of Medicine.

19 Apr 2006

miR 155 overexpression can lead to cancer

Scientists in the Ohio State University Comprehensive Cancer Center say that just one, single, malfunctioning microRNA is sufficient to cause cancer in mice.

18 Apr 2006

Bone Marrow News and Research

Further Reading

SuperGen receives patent for composition and method for treating graft-versus-host disease

Finding opens new pathways for treating or preventing autoimmune diseases

Research could lead to new treatments for idiopathic pulmonary fibrosis

Adult survivors of childhood cancer and unemployment

Study sheds light on cancer susceptibility and disease involving bone-marrow failure

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

New treatment for chronic eosinophilic leukemia

Stem cell 'fusion' occurs in tumors

Circulating tumor cells in the bone marrow of patients with metastatic renal cell carcinoma may be prognostic of outcome

Discovery of new type of cell that generates crucial immune system cells

Differential effects of HOXB4 on nonhuman primate short and long-term repopulating cells

Protein produced by immune cells during malaria infection triggers severe anemia

Tumour specific drugs may render therapies based on a tumor's anatomical location obsolete

Transplanted stem cells hoped to be able to regenerate damaged heart muscle in first heart attack victims

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

Blood cancers may be caused by inactivation of a "tumor suppressor" gene

New method designed to analyze the genes that regulate the immune system

Discovery points to more effective ways of regulating cell signalling

New finding provides researchers with renewable source for macrophages and neutrophils

miR 155 overexpression can lead to cancer

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