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High-dose chemo does not improve survival in small cell lung cancer

Small cell lung cancer (SCLC) patients treated with high-dose chemotherapy did not have better survival rates than those treated with standard doses, according to a randomized controlled trial published online April 8 in the Journal of the National Cancer Institute .

9 Apr 2008

Rreishi mushroom and green tea for cancer prevention

Both the reishi mushroom (Ganoderma lucidum; Lingzhi) and green tea have long held a place in traditional medicine in China and other Asian countries, for the general promotion of health and long life and for the treatment of specific diseases.

9 Apr 2008

Double binding sites on tumor target may provide future combination therapy

Researchers from the University of Pennsylvania School of Medicine and colleagues at Merck Serono Research in Germany have found that two drugs bind to receptor sites on some tumors in different places at the same time, suggesting the possibility of a new combination therapy for certain types of cancer.

9 Apr 2008

Diabetes drug may hold potential as treatment for epilepsy, using same mechanism as ketogenic diet

Two years ago, University of Wisconsin-Madison scientists reported they had suppressed epileptic seizures in rats by giving them a glycolytic-inhibitor, inhibiting the brain's ability to turn sugar into excess energy and blocking the expression of seizure-related genes.

9 Apr 2008

Combination therapy improves survival time for patients with more advanced liver cancer

Combining a type of chemotherapy with radiothermal therapy resulted in longer survival time for patients with advanced liver cancer, compared to receiving the therapies alone, according to a study in the April 9 issue of JAMA, the Journal of the American Medical Association.

9 Apr 2008

Cholesterol, blood pressure control may reverse atherosclerosis in adults with diabetes

Aggressively lowering cholesterol and blood pressure levels below current targets in adults with type 2 diabetes may help to prevent – and possibly reverse – hardening of the arteries, according to new research supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

9 Apr 2008

Angina drug ranolazine potentially useful against heart rhythm disorders

A recently approved angina drug may also represent a powerful new treatment for a rare hereditary syndrome that places teens at risk for sudden cardiac death, according to research presented on April 1st at the 57th Annual Scientific Sessions of the American College of Cardiology (ACC) in Chicago.

9 Apr 2008

Parkinson transplants survive at least 16 years

Transplanted cells can survive in the brain for over one and half decade. However, some of the transplanted cells developed Parkinson-like features which is very surprising.

9 Apr 2008

Benefits of some cancer drugs exaggerated because trials were stopped early

Italian scientists say the benefits of some cancer drugs may be exaggerated as a rising number of trials are stopped early.

9 Apr 2008

Biological link between pain and fatigue discovered

A recent University of Iowa study reveals a biological link between pain and fatigue and may help explain why more women than men are diagnosed with chronic pain and fatigue conditions like fibromyalgia and chronic fatigue syndrome.

8 Apr 2008

Testosterone replacement theraphy for senior men beneficial

The risk of osteoporosis (bone fracture) in women is highly recognized by the public.

8 Apr 2008

Potential new therapy for myeloproliferative disorders

A unique partnership between industry and academia has led to human clinical trials of a new drug for a rare class of blood diseases called myeloproliferative disorders (MPD), which are all driven by the same genetic mutation and can evolve into leukemia.

8 Apr 2008

Malfunctioning kidneys may raise risk of sudden death in women

Women whose kidneys are poor at filtering impurities from the blood are at heightened risk of sudden cardiac death, according to a report published in Hypertension: Journal of the American Heart Association.

8 Apr 2008

Rare genetic variants have big impact on blood pressure

Yale University researchers report in the journal Nature Genetics that they have discovered that rare genetic variants can be associated with a dramatically lower risk of developing high blood pressure in the general population.

7 Apr 2008

Scientists visualize the machinery of mRNA splicing

Recent research at Yale provided a glimpse of the ancient mechanism that helped diversify our genomes; it illuminated a relationship between gene processing in humans and the most primitive organisms by creating the first crystal structure of a crucial self-splicing region of RNA.

7 Apr 2008

T-cadherin affects blood vessel growth in breast cancer, hormone from fat cells may play a role

Researchers at the Burnham Institute for Medical Research (Burnham) may have found a new option for targeted breast cancer therapy by showing the link between a certain protein and the formation and development of blood vessels that feed breast tumors.

7 Apr 2008

Cholesterol in Parkinson's disease

In 2006, University of North Carolina at Chapel Hill researchers published a study that found people with low levels of LDL cholesterol are more likely to have Parkinson's disease than people with high LDL levels.

7 Apr 2008

Pediatricians alerted to the developmental nature of underage drinking in special journal supplement

In a special supplement to Pediatrics, edited and sponsored by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), physicians will have access in one place to the reviews and analyses of current research on biological, behavioral, and environmental changes during childhood and adolescence that foster the initiation, maintenance, and acceleration of illegal use of alcohol by underage youth.

7 Apr 2008

Occupational therapists use Wii for Parkinson's study

It's Ingrid Bell's turn at bat. She steps up to the plate, awaiting the pitch. A 70-mph fastball soars toward her. She swings and connects with the ball.

7 Apr 2008

Cancer treatment from a common avian virus under study

Researchers on the Blacksburg and College Park, Maryland campuses of the Virginia-Maryland Regional College of Veterinary Medicine have been awarded a major new grant from the National Institutes of Health (NIH) to support innovative work that seeks to develop a treatment for cancer from a common avian virus.

7 Apr 2008