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Stem cell breakthrough offers diabetes hope

Scientists have discovered a new technique for turning embryonic stem cells into insulin-producing pancreatic tissue in what could prove a significant breakthrough in the quest to find new treatments for diabetes.

From The University of Manchester 4 Apr 2008

Enzyme complex could be key to new cancer treatments

Penn State scientists are the first to observe in living cells a key step in the creation of adenine and guanine, two of the four building blocks that comprise DNA.

4 Apr 2008

Genetic mutations tied to immune comeback during therapy for HIV-1

Researchers with the Infectious Disease Clinical Research Program (IDCRP) at the Uniformed Services University of the Health Sciences (USU) here and the University of Texas Health Science Center at San Antonio have published a patient outcome study in the March 30 online edition of Nature Medicine that may signal a need for a change of thought in the management of HIV.

3 Apr 2008

How to reduce fibromyalgia pain

Pain all over, fatigue and difficulty sleeping -- and no measurable answer for what could be wrong.

3 Apr 2008

Cellular grafting procedure helps young patients with knee disorder get active

At 14 years old, Adam Vasser of Los Altos, Calif., was an active kid who loved baseball.

2 Apr 2008

New clues to risk of Hodgkin lymphoma discovered

A long-term study of twins has led University of Southern California (USC) researchers to find potential links between Hodgkin lymphoma and levels of an immune response protein (interleukin-12).

2 Apr 2008

Light-powered nanomachine kills cancer cells

Researchers from the Nano Machine Center at the California NanoSystems Institute at UCLA have developed a novel type of nanomachine that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light.

2 Apr 2008

Angioplasty and stenting for renal artery lesions

The largest-ever randomized study to evaluate the effectiveness of catheter-based interventions in patients with narrowing of the renal artery has shown that angioplasty and stenting offer no benefit over medical therapy.

2 Apr 2008

Newly identified gene may prompt pancreas cells to form

Before a pancreas is a pancreas, it?s part of the endoderm, one of three layers of cells in a developing embryo that eventually form its organs.

2 Apr 2008

Synthetic progestin linked to breast cancer

Millions of post-menopausal women use hormone replacement therapy (HRT) as a method to reduce symptoms associated with menopause.

2 Apr 2008

Catheter repair of mitral valve improves heart size, symptoms

A catheter-mounted device that acts like a clothespin to clip together the flaps of a leaky heart valve is not only reducing the abnormal backflow of blood from the left ventricle to the left atrium, it is helping to shrink the enlarged, overworked heart and relieving symptoms of fluid overload - all without open-chest surgery.

2 Apr 2008

Study results on novel drug-eluting stent coated with a biodegradable polymer

"Real-world" use of a novel drug-eluting stent coated with a biodegradable polymer is associated with good clinical outcomes, according to one-year data from a large international registry.

1 Apr 2008

A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics

Results of a randomised trial published in PLoS Medicine show no benefit in cognitive or neuropsychiatric outcomes from continuing neuroleptic drugs in patients with Alzheimer's disease.

1 Apr 2008

New research shows benefits of ultrasound contrast agents outweigh potential risk to heart patients

A Saint Louis University cardiologist called upon the U.S. Food and Drug Administration (FDA) today to reconsider a strong warning it recently placed on a diagnostic tool, stating that the warning could prevent doctors from detecting life-threatening cardiac events.

1 Apr 2008

Diabetics have same risk for heart attack, stroke or death from cardiovascular diseases

People with diabetes have the same high risk for heart attack or stroke or cardiovascular death as people who've already had a heart attack, researchers reported in Circulation: Journal of the American Heart Association.

1 Apr 2008

Childhood leukemia survivors struggle with long-term comorbidities

Survival rates of childhood cancers, especially leukemia, have improved greatly in the past three decades, but survivors of this disease still seem to face many health and lifestyle challenges as young adults.

1 Apr 2008

Replacing absent microRNAs could make tumors less invasive, more treatable

One group of small, non-coding RNA molecules could serve as a marker to improve cancer staging and may also be able to convert some advanced tumors to more treatable stages, report a University of Chicago-based research team in the April 1, 2008, issue of the journal Genes & Development.

1 Apr 2008

New blood pressure drug telmisartan has fewer side effects

A major Canadian-led global study has found that a new blood pressure medication is effective in reducing cardiovascular death, with fewer side effects than the current standard of care.

1 Apr 2008

Naglazyme approved in Japan

BioMarin Pharmaceutical Inc. has announced that AnGes MG, Inc. (AnGes), BioMarin's marketing and distribution partner in Japan, has received approval for its Marketing Application for Naglazyme(R) (galsulfase) from the Japanese Ministry of Health, Labour and Welfare (MHLW) for the treatment of patients with Mucopolysaccharidosis VI ( MPS VI).

1 Apr 2008

Matrix registry probes adherence to clopidogrel at 1 year

A large community-based registry of patients treated with drug-eluting stents is providing important insight into how long patients with complex coronary artery disease typically stick to their doctors' orders to take clopidogrel, a drug that prevents unwanted blood clots; why they stop taking the drug; and the long-term consequences of that decision.

1 Apr 2008