Therapy News and Research

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Depression is not always manifested in children as dejection and anhedonia

Depending on the age of the child, the dominant features may be weeping, irritability or defiance, as explained by Prof. Claudia Mehler-Wex and Dr. Michael Kölch of Ulm University in the new edition of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2008; 105(9): 149-55).

17 Mar 2008

Study explains fundamental process of tumor growth

Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

14 Mar 2008

Psychological intervention reduces postembolization pain

Psychological intervention has been shown to reduce the postembolization pain during hepatic arterial chemoembolizatiom therapy.

14 Mar 2008

MGH initiates trial to reverse type 1 diabetes

Scientists at the Massachusetts General Hospital (MGH) have initiated a phase 1 clinical trial to reverse type 1 diabetes.

14 Mar 2008

Low cost tactics improve medication use after heart attack

Direct-to-patient communication about the importance of continuing prescription drug treatment after a heart attack is a simple, low-cost way to increase the likelihood of patients adhering to life saving therapies at least four out of every five days.

14 Mar 2008

Long-term muscle improvements shown in gene therapy study in mice

Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows.

14 Mar 2008

Lilly and Transition Therapeutics announce licensing and collaboration agreement

Eli Lilly and Company and Transition Therapeutics Inc. has announced that the two companies have entered into a licensing and collaboration agreement granting Lilly exclusive worldwide rights to develop and commercialize Transition's gastrin based therapies, including the lead compound TT-223, which is currently in early Phase II testing.

14 Mar 2008

Cause of prolonged penile erection

Priapism (prolonged penile erection in the absence of sexual interest) is common in male individuals with sickle cell disease (SCD), a blood disorder characterized by abnormally shaped red blood cells.

14 Mar 2008

Is deep-vein thrombosis lurking in your legs?

They kill 300,000 people a year - but most of them could be prevented. They strike more than a million people every year, most of them out of the blue - and half without causing symptoms.

14 Mar 2008

Treatment of obsessive-compulsive disorder, help for partners also

Most people occasionally worry about germs, strange noises in the night, or whether they forgot to turn off the oven before leaving on vacation.

14 Mar 2008

Researchers find benefit for lymphoma patients in combined PET-CT scanning

Combined positron emission tomography (PET) and computed tomography (CT) imaging of lymphoma patients is a more effective method to evaluate response to radiation therapy, and may help patients avoid unnecessary follow-up treatments, a study by researchers at the University of Southern California (USC) suggests.

13 Mar 2008

Study helps explain how tumor cells rapidly grow and proliferate

Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

13 Mar 2008

Researchers find cause of severe allergic reaction to cetuximab

Clinicians have been perplexed by the fact that some patients given the drug cetuximab - an immune-based therapy commonly used to treat persons diagnosed with head and neck cancer, or colon cancer - have a severe and rapid adverse reaction to the drug.

13 Mar 2008

Protein deficiency leads to faster fat burning in mice, study shows

Researchers have developed a new, lean mouse with characteristics suggesting that someday, using medication to manipulate a specific protein in humans could emerge as a strategy to treat obesity and disorders associated with excess weight, such as diabetes and metabolic syndrome.

13 Mar 2008

Implantable medical devices may expose patients to security, privacy risks; solutions suggested

Some medical devices such as implantable cardiac defibrillators and pacemakers are now equipped with wireless technology, allowing for remote device checks and freeing patients from repeated doctor visits.

13 Mar 2008

Good news for people with glycogen storage disease type Ia

A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans, according to Duke University Medical Center researchers.

13 Mar 2008

AstraZeneca completes enrollment in phase III studies of cancer drug vandetanib

AstraZeneca has announced that it has completed patient enrollment in two pivotal Phase III studies for vandetanib, the company's investigational, once-daily oral anti-cancer drug, for the second-line treatment of non-small cell lung cancer (NSCLC).

13 Mar 2008

DNA detectives find genetic markers for lung cancers most likely to recur

Researchers at the Johns Hopkins Kimmel Cancer Center have uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early-stage lung cancers that look like good predictors of which of these cancers are more likely to recur.

13 Mar 2008

World's newest flexible drug-eluting stent used by Methodist cardiologists

A more flexible drug-eluting stent studied in clinical trials at the Methodist DeBakey Heart & Vascular Center has been approved by the FDA, and Methodist physicians were the first in Houston to implant the new device.

12 Mar 2008

Weight loss more effective than intensive insulin therapy for type 2 diabetics

Weight-loss and major lifestyle changes may be more effective than intensive insulin therapy for overweight patients with poorly controlled, insulin-resistant type 2 diabetes, according to a diabetes researcher at UT Southwestern Medical Center.

12 Mar 2008