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Researchers may have found test for depression

Researchers from the University of Illinois at Chicago College of Medicine have discovered that a change in the location of a protein in the brain could serve as a biomarker for depression, allowing a simple, rapid, laboratory test to identify patients with depression and to determine whether a particular antidepressant therapy will provide a successful response.

12 Mar 2008

New discovery could change future diagnosis and therapy of depression

12 Mar 2008

Postoperative chemotherapy does not improve survival in gastric cancer patients

The use of combination chemotherapy following surgery did not improve survival in patients with gastric cancer, according to a randomized clinical trial published online March 11 in the Journal of the National Cancer Institute .

12 Mar 2008

Switch for programmed cell death promotes spread of glioblastoma

Malignant tumors have usually lost their ability to destroy themselves by programmed cell death, or apoptosis.

12 Mar 2008

Researchers find treatment for familial cold autoinflammatory syndrome

Dalhousie Medical School dermatologist Dr. Barrie Ross and his colleagues have successfully ended a 20-year quest to find a treatment for Familial Cold Autoinflammatory Syndrome (FCAS).

12 Mar 2008

Combined therapeutic approach of stenting and photodynamic therapy improves survival in late stage liver cancer patients

A combined therapeutic approach of stenting and photodynamic therapy may improve survival rates for patients suffering from advanced liver bile duct cancer, according to a study published this month in Clinical Gastroenterology and Hepatology , the official journal of the American Gastroenterological Association (AGA) Institute.

12 Mar 2008

Weight-loss more effective than intensive insulin therapy for type 2 diabetics, according to expert

Weight-loss and major lifestyle changes may be more effective than intensive insulin therapy for overweight patients with poorly controlled, insulin-resistant type 2 diabetes, according to a diabetes researcher at UT Southwestern Medical Center.

11 Mar 2008

Virtual reality therapy for stroke patients

Israeli hospitals have recently started to use virtual reality therapy for stroke patients.

11 Mar 2008

Potential new gene therapy strategy for muscle-wasting diseases

Investigators in The Research Institute at Nationwide Children's Hospital have identified the role of a protein that could potentially lead to new clinical treatments to combat musculoskeletal diseases, including Duchenne muscular dystrophy (DMD).

11 Mar 2008

Recurrent low-grade carcinoma of the ovary less responsive to chemo than more common ovarian cancers

Recurrent low-grade serous carcinoma, a rare type of ovarian cancer, is less sensitive to chemotherapy and therefore more difficult to treat than more common high-grade ovarian cancers, according to researchers from The University of Texas M. D. Anderson Cancer Center.

11 Mar 2008

Post-stroke clot-busting therapy beneficial for patients on aspirin

Patients given a clot-busting drug following stroke appear to have better outcomes if they were already taking anti-platelet medications, despite an apparent increased risk for bleeding in the brain, according to an article posted online that will appear in the May 2008 print issue of Archives of Neurology.

11 Mar 2008

Poor sleep more dangerous for women

Researchers at Duke University Medical Center say they may have figured out why poor sleep does more harm to cardiovascular health in women than in men.

11 Mar 2008

Survival rates for patients for with non-Hodgkin lymphoma improved over past decade

Five- and 10-year survival rates for patients with non-Hodgkin lymphoma appear to have increased from the 1990s to the early 21st century, according to a report in the March 10 issue of Archives of Internal Medicine.

11 Mar 2008

Long-term effects of synthetic progestins cause for concern

The widely used synthetic progestin medroxyprogesterone acetate (MPA) decreased endothelial function in premenopausal women in a study done at the University of Oregon.

11 Mar 2008

Observational study of severe osteoporosis

Women who do not comply with treatment instructions for osteoporosis or who do not respond to treatment are more likely to suffer further fractures, which seriously affects their quality of life.

11 Mar 2008

Long-term muscle improvements shown in gene therapy study in mice

Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows.

11 Mar 2008

Late treatment with letrozole (Femara) can reduce breast cancer recurrence risk

Treatment with the aromatase inhibitor letrozole (Femara) can reduce the risk of breast cancer recurrence even when initiated one to seven years after a course of tamoxifen therapy.

11 Mar 2008

Cell therapy for rejuvenating aged brain by injection of human umbilical cord blood

When human umbilical cord blood cells (UCBC) were injected into aged laboratory animals, researchers at the University of South Florida (USF) found improvements in the microenvironment of the hippocampus region of the animals' brains and a subsequent rejuvenation of neural stem/progenitor cells.

11 Mar 2008

Gender bias may affect care of people with osteoarthritis

Unconscious prejudices among doctors may explain why women complaining of knee pain are less likely than men to be recommended for total knee replacement surgery, a study in the current issue of the Canadian Medical Association Journal suggests.

11 Mar 2008

Femara helps protect against return of breast cancer after completing Tamoxifen therapy

Women may reduce the risk of their breast cancer returning by starting treatment with Femara (letrozole tablets) anywhere from one to seven years after finishing tamoxifen therapy, according to a new analysis published in the Journal of Clinical Oncology.

11 Mar 2008