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Researchers uncover new therapeutic opportunity in the treatment of malignant melanoma

A team of researchers led by Dr Pierre Close, WELBIO researcher at the ULiège GIGA Institute and Dr Francesca Rapino has uncovered a new therapeutic opportunity in the treatment of malignant melanoma that acquired resistance to targeted therapies.

21 Jun 2018

New therapeutic approach may delay neurodegeneration in rare genetic disease

A new therapeutic approach may one day delay neurodegeneration typical of a disease called mucopolysaccharidoses IIIB. Neurodegeneration in this condition results from the abnormal accumulation of essential cellular molecules called mucopolysaccharides.

21 Jun 2018

UT Southwestern scientists identify gene mutation linked with perplexing brain condition

Scientists conducting one of the largest full DNA analyses of a rare disease have identified a gene mutation associated with a perplexing brain condition that blinds and paralyzes patients.

20 Jun 2018

Researchers employ nucleotide-based gene silencing to mitigate common ataxia

In what researchers are calling a game changer for future ataxia treatments, a new study showed the ability to turn down the disease progression of the most common dominantly inherited ataxia.

20 Jun 2018

Combining stem cell technology and artificial intelligence to diagnose genetic cardiac diseases

A new study by Professors Martti Juhola and Katriina Aalto-Setälä of the University of Tampere in Finland demonstrates that with the use of artificial intelligence and machine learning, it is possible not only to accurately sort sick cardiac cell cultures from healthy ones, but also to differentiate between genetic cardiac diseases.

20 Jun 2018

Scientists identify novel genes linked with infantile forms of schizophrenia

Scientists at the Montreal Neurological Institute and Hospital and McGill University have identified novel genes associated with a specific form of schizophrenia.

19 Jun 2018

Unusual gene provides novel insight into how the brain wires itself

The study of a Quebec family with an unusual gene provides novel insight into how our brain is built and, according to the McGill led team of scientists, offers a better understanding of psychiatric disorders such as depression, addictions, and schizophrenia.

19 Jun 2018

Study shows how moderate consumption of alcohol can protect the heart

For at least 20 years, research has shown that for many people, moderate consumption of alcohol can protect the heart, but the reason for this is poorly understood.

18 Jun 2018

Study finds more information about how gene linked to ASD affects the brain

New preclinical research shows a gene already linked to a subset of people with autism spectrum disorder is critical to healthy neuronal connections in the developing brain, and its loss can harm those connections to help fuel the complex developmental condition.

18 Jun 2018

Scientists discover genetic causes underlying group of related infant cancers

The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators.

18 Jun 2018

Researchers identify gene enhancer that affects sex determination

Researchers have identified a gene enhancer that is critical for male sex development and shown that deleting it results in male-to-female sex reversal in mice.

15 Jun 2018

Charity introduces new Hereditary Cancer Risk Tool to fight ovarian cancer

Around 15% of ovarian cancer cases are linked to genetic mutations such as BRCA1, BRCA2 and Lynch Syndrome, which increase an individual's likelihood of developing ovarian and other cancers. This equates to over 1,000 women a year in the UK whose lives could potentially be saved.

13 Jun 2018

Study uncovers new molecular mechanisms of Parkinson's disease

Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease.

12 Jun 2018

Scientists discover first genetic marker for bone tumor

The first genetic marker for the bone tumor, osteoblastoma, has been discovered by scientists at the Wellcome Sanger Institute and their collaborators.

12 Jun 2018

Deep-frozen juices defrosted to room temperature can increase carotenoids level in body

Researchers from the Laboratory of Food Color and Quality at the University of Seville have published a study in which it is shown how certain types of cold treatment that are used by the citrus fruits industry in the preparation of juices have a great impact on the color of orange juice and on the concentration and bioaccessibility of the carotenoids present in the juice.

11 Jun 2018

Genetic mutation shown to cause bipolar disorder

Researchers have discovered a mutation that may increase the risk of bipolar disorder through a complex interplay between serotonin and mitochondrial signaling.

11 Jun 2018

ANT1 mutations connect bipolar disorder with mitochondrial dysfunction

Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain.

11 Jun 2018

Study reveals mechanism behind eye loss in blind cavefish

Blind cavefish lose critical eye tissues within a few days after their eyes begin to develop.

7 Jun 2018

Naturally occurring antibody can block inflammation in mice, finds study

Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids, molecules on cell surfaces that get modified by inflammation.

7 Jun 2018