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Study finds significant reduction in diabetes-related amputation rates since the mid-1990s

A major new study has found a significant reduction in diabetes-related amputations since the mid-1990s, credited to improvements in diabetes care over this period. The research is published in Diabetologia (the journal of the European Association for the Study of Diabetes) and is by Dr Benjamin Rasmussen and Professor Henning Beck-Nielsen, Odense University Hospital Denmark, and colleagues.

23 Nov 2015

Ninlaro (ixazomib) approved to treat people with multiple myeloma

Today the U.S. Food and Drug Administration granted approval for Ninlaro (ixazomib) in combination with two other therapies to treat people with multiple myeloma who have received at least one prior therapy.

21 Nov 2015

Interaction between two brain proteins has substantial effect on memory formation

In a new study that could have implications for future drug discovery efforts for a number of neurodegenerative diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that the interaction between a pair of brain proteins has a substantial and previously unrecognized effect on memory formation.

20 Nov 2015

UF Health investigators make new discovery about Huntington's disease

University of Florida Health researchers have made a new discovery about Huntington's disease, showing that the gene that causes the fatal disorder makes an unexpected "cocktail" of mutant proteins that accumulate in the brain.

19 Nov 2015

Researchers find mechanism to repair communication between neurons

A team of researchers led by professor Patrik Verstreken (VIB/KU Leuven) has exposed the fine details of a mechanism that provides more insight in the communication between neurons. The research has clarified how damaged synapses - the connection points between neurons - are repaired to keep communication between neurons at an optimal level.

19 Nov 2015

Sound deprivation causes irreversible damage to the inner ear

Massachusetts Eye and Ear investigators have shown that sound deprivation in adult mice causes irreversible damage to the inner ear. The findings, published in PLOS ONE, suggest that chronic conductive hearing loss, such as that caused by recurrent ear infections, leads to permanent hearing impairment if it remains untreated.

19 Nov 2015

Scientists succeed in promoting regeneration of injured neurons in zebrafish by the use of light

The nervous system is built to last a lifetime, but diverse diseases or environmental insults can overpower the capacity of neurons to maintain function or to repair after trauma. A team led by Dr. Hernán López-Schier, head of the Research Unit Sensory Biology and Organogenesis at Helmholtz Zentrum München, now succeeded in promoting the repair of an injured neural circuit in zebrafish.

18 Nov 2015

Study provides biochemical links between genes linked to autism and the inhibition of nerve cells

A study led by the University of Utah School of Medicine provides new insights into how the subtle changes within cells, caused by disruptions in a gene called Kirrel3, could underlie some types of intellectual disability and autism.

18 Nov 2015

$HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery$

HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery

Researchers at Hospital for Special Surgery have launched a study to determine if a novel implant allowing for less invasive surgery for a broken wrist leads to a quicker recovery, less post-operative pain and fewer complications compared to conventional surgical treatment.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

MedUni Vienna researchers discover genetic cause of a rare disease

Researchers at MedUni Vienna have discovered the genetic cause of a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when they reach school age.

15 Nov 2015

Research collaboration aims to develop new drug for slow-healing chronic wounds

The biotech company Omnio based in Swedish Umeå, and led by researcher Tor Ny at Umeå University, launches a research collaboration with the Canadian pharmaceutical company ProMetic to develop a new drug for slow-healing chronic wounds. The collaboration includes funding for clinical studies of a drug based on the blood plasma protein plasminogen.

15 Nov 2015

Inner ear damage brain warnings from nerve cells

Some nerve cells in the inner ear can signal tissue damage in a way similar to pain-sensing nerve cells in the body, according to new research from Johns Hopkins.

10 Nov 2015

VISERA 4K UHD endoscopy system gives surgeons 4x resolution

Olympus launches the VISERA 4K UHD system across the UK. Surgeons will benefit from particularly sharp images thanks to integration of 4K Ultra HD technology.

From Evident - Medical and Surgical 10 Nov 2015

Possible reasons found for Alzheimer’s treatment failure

Agglutinated proteins in the brain, known as amyloid-β plaques, are a key characteristic of Alzheimer’s. One treatment option uses special antibodies to break down these plaques.

10 Nov 2015

Protein sensor for proprioception found

Can you touch a finger to the tip of your nose with your eyes closed? Most of us can, thanks to a sense called proprioception, which tells us where our body parts are relative to each other and our environment. Not surprisingly, this sense is essential for normal movement and balance—walking, for instance.

10 Nov 2015

Genetic reduction of AMPK enzyme can prevent or delay hearing loss

A mitochondrial defect is responsible for a type of human hereditary deafness that worsens over time and can lead to profound hearing loss.

6 Nov 2015

Researchers successfully repair nerve cell damage in Alzheimer's dementia

In laboratory experiments on the basic mechanisms that cause Alzheimer's dementia, an international research team led by Heidelberg neurobiologist Prof. Dr. Ulrike Müller and a team of French scientists have succeeded in largely "repairing" the nerve cell damage typical in this disease.

5 Nov 2015

Study suggests need for specific treatment options for adolescents with onset type 2 diabetes

New results from the Treatment Options for Type 2 Diabetes in Youth study (TODAY) examined predictors of the outcomes in youth with onset type 2 diabetes (T2D) based on early characteristics at diagnosis, and suggests the need for specific criteria for adolescents that are different from those in adults.

5 Nov 2015

Allergan signs licensing agreement with Mimetogen to develop, commercialize tavilermide for treatment of dry eye disease

Allergan plc, a leading global pharmaceutical company, today announced that its wholly owned subsidiary has entered into an exclusive licensing agreement with Mimetogen Pharmaceuticals, a clinical stage biotechnology company, to develop and commercialize tavilermide (MIM-D3), a topical formulation of a novel small molecule TrkA agonist for the treatment of dry eye disease.

4 Nov 2015

Nerve News and Research

Study finds significant reduction in diabetes-related amputation rates since the mid-1990s

Ninlaro (ixazomib) approved to treat people with multiple myeloma

Interaction between two brain proteins has substantial effect on memory formation

UF Health investigators make new discovery about Huntington's disease

Researchers find mechanism to repair communication between neurons

Sound deprivation causes irreversible damage to the inner ear

Scientists succeed in promoting regeneration of injured neurons in zebrafish by the use of light

Study provides biochemical links between genes linked to autism and the inhibition of nerve cells

HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

MedUni Vienna researchers discover genetic cause of a rare disease

Research collaboration aims to develop new drug for slow-healing chronic wounds

Inner ear damage brain warnings from nerve cells

VISERA 4K UHD endoscopy system gives surgeons 4x resolution

Possible reasons found for Alzheimer’s treatment failure

Protein sensor for proprioception found

Genetic reduction of AMPK enzyme can prevent or delay hearing loss

Researchers successfully repair nerve cell damage in Alzheimer's dementia

Study suggests need for specific treatment options for adolescents with onset type 2 diabetes

Allergan signs licensing agreement with Mimetogen to develop, commercialize tavilermide for treatment of dry eye disease

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