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Drug therapy for phenylketonuria reverses heart damage

A pricy drug used to treat a rare but well-known genetic disorder may hold wider promise as a treatment for millions of Americans with potentially lethal enlarged hearts, due mainly to high blood pressure, a study from Johns Hopkins shows.

13 May 2008

Vitamin D protects cells from stress that can lead to cancer

By inducing a specific gene to increase expression of a key enzyme, vitamin D protects healthy prostate cells from the damage and injuries that can lead to cancer, University of Rochester Medical Center researchers report.

13 May 2008

Traffic pollution can be deadly as it increases the risk of deep vein thrombosis

Scientists in the U.S. have confirmed a long held suspicion that traffic pollution can be deadly for some people.

13 May 2008

Beta blockers after surgery more risky than beneficial

The results of new research has shown that patients given high doses of beta blocker drugs following non-cardiac surgery were more likely to have a stroke or die. However they were less likely to suffer a heart attack.

13 May 2008

Arsenic-based agent shown to help eradicate leukemia-initiating cells

In both leukemia and solid tumors, there exists among the multitude of warrior cancer cells a small subgroup that work undercover, patiently lying in wait to launch their attacks. Known as either cancer initiating cells (CICs) or leukemia initiating cells (LICs), these stealth populations are impervious to conventional chemotherapy and undaunted by targeted cancer therapies. When a leukemia patient relapses following a period of remission, it is the LICs that bear responsibility for the disease's reemergence.

12 May 2008

Discovery of gene mutation which causes epilepsy and mental retardation - but only in women

An Australian and British research team have discovered a gene mutation that causes epilepsy and mental retardation but only in women.

12 May 2008

Discovery of mechanism of action of antibiotic able to reduce neuronal cell death in brain

Virginia Commonwealth University researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer's disease, Huntington's disease, epilepsy, stroke, dementia and malignant gliomas.

11 May 2008

Study affirms effectiveness of medication for juvenile rheumatoid arthritis

Juvenile rheumatoid arthritis (JRA) is a chronic autoimmune disease that strikes children between the ages of newborn to 16 years. All children with JRA have joint pain, stiffness, and swelling and some also have fever and skin rashes.

9 May 2008

FDA approves Strattera for ADHD in children and adolescents

Eli Lilly and Company announced today that the United States Food and Drug Administration (FDA) has approved Strattera (atomoxetine HCI) for maintenance treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children and adolescents. Strattera, a selective norepinephrine reuptake inhibitor, is the first FDA-approved non-stimulant to treat ADHD in children, adolescents and adults.

8 May 2008

Skin flaps deliver cancer-fighting therapy

Using gene therapy, plastic surgeons have delivered cancer fighting proteins through skin flaps placed on cancerous tumors on rats with a 79 percent reduction in tumor volume, according to a study in the May issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

8 May 2008

Medicare fee cuts could devastate rehabilitation services

Pending cuts to the Medicare physician fee schedule could severely hamper the ability of physical therapists to serve the rehabilitation needs of seniors and people with disabilities -- driving up overall costs while decreasing quality of care, according to the American Physical Therapy Association (APTA) and its Private Practice Section.

8 May 2008

ART drugs for pregnant women eradicates baby's risk of HIV

Researchers in Britain say a baby's risk of contracting HIV from its mother can be almost eradicated with the use of antiretroviral drugs.

8 May 2008

Vitamin D linked to reduced mortality rate in chronic kidney disease

For patients with moderate to severe chronic kidney disease (CKD), treatment with activated vitamin D may reduce the risk of death by approximately one-fourth, suggests a study in the August Journal of the American Society of Nephrology.

7 May 2008

Role of genetic components of dendritic cells could lead to more effective drugs

For the first time, researchers from the University of Pittsburgh School of Medicine have identified genetic components of dendritic cells that are key to asthma and allergy-related immune response malfunction. Targeting these elements could result in more effective drugs to treat allergic disorders and asthma, according to a study reported in the May edition of the journal Nature Medicine.

7 May 2008

Enkephalin pathway shows potential as new target for Alzheimer's

Alzheimer's disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed.

7 May 2008

Medical research is essential to improving the economy and bettering lives

Health care in the United States is expensive, but its funding is crucial because it also is a major contributor to the economy and can better lives, according to an essay appearing in the June 2008 issue of the Journal of the American Society Nephrology (JASN). Because of the cost of health care, this is not time to shrink the budget at the National Institutes of Health, which funds medical research that leads to potentially curative therapy.

7 May 2008

Antidepressants do work in depression while evidence for cognitive behavioural yherapy is poorer say experts

A new revision of clinical guidelines to help doctors manage patients with depression has challenged the rationale behind the UK government's policy of rolling out of cognitive behavioural therapy (CBT) for milder depression.

7 May 2008

Nurse care for schizophrenia patients

Drug and psychosocial interventions for the symptoms of schizophrenic disorders contribute to a lower incidence and prevalence of schizophrenia. Nurses will be able to offer better care through the use of nursing models and theories in the care of Schizophrenics.

6 May 2008

Russia should increase HIV prevention efforts targeted at IDUs, UNAIDS Executive Director Piot says

Russia should increase efforts to address HIV/AIDS among injection drug users to slow the spread of the disease, UNAIDS Executive Director Peter Piot said on Saturday during a conference on HIV/AIDS in the former Soviet Union, Reuters reports. According to Reuters, the former Soviet Union has the third-highest number of people living with HIV/AIDS worldwide.

6 May 2008

Corticosteroids not linked with reduced risk of death for children with bacterial meningitis

Use of corticosteroids in addition to other treatment for children with bacterial meningitis is not associated with a decreased risk of death or shorter hospital stay, according to a study in the May 7 issue of JAMA, the Journal of the American Medical Association.

6 May 2008

Therapy News and Research

Drug therapy for phenylketonuria reverses heart damage

Vitamin D protects cells from stress that can lead to cancer

Traffic pollution can be deadly as it increases the risk of deep vein thrombosis

Beta blockers after surgery more risky than beneficial

Arsenic-based agent shown to help eradicate leukemia-initiating cells

Discovery of gene mutation which causes epilepsy and mental retardation - but only in women

Discovery of mechanism of action of antibiotic able to reduce neuronal cell death in brain

Study affirms effectiveness of medication for juvenile rheumatoid arthritis

FDA approves Strattera for ADHD in children and adolescents

Skin flaps deliver cancer-fighting therapy

Medicare fee cuts could devastate rehabilitation services

ART drugs for pregnant women eradicates baby's risk of HIV

Vitamin D linked to reduced mortality rate in chronic kidney disease

Role of genetic components of dendritic cells could lead to more effective drugs

Enkephalin pathway shows potential as new target for Alzheimer's

Medical research is essential to improving the economy and bettering lives

Antidepressants do work in depression while evidence for cognitive behavioural yherapy is poorer say experts

Nurse care for schizophrenia patients

Russia should increase HIV prevention efforts targeted at IDUs, UNAIDS Executive Director Piot says

Corticosteroids not linked with reduced risk of death for children with bacterial meningitis

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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