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Swedish measurement method to be used as standard in Alzheimer's diagnostics worldwide

Researchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before symptoms appear. The method has now formally been classified as the international reference method, which means that it will be used as the standard in Alzheimer's diagnostics worldwide.

4 Nov 2015

Oxford professor wins Heinrich Wieland Prize for pioneering method that helps control nerve cells with light

Gero Miesenböck was the first to insert a light-controlled on/off switch into brain cells. His pioneering method allows scientists to switch nerve cells on and off selectively and observe how the behaviour of, for example, fruit flies or mice changes as a result. In this way, researchers can learn in a step-by-step process what behaviour the studied brain circuits control and what goes awry in disease. For his method, hailed as a "breakthrough of the decade," Professor Gero Miesenböck of the University of Oxford will receive the 100,000-euro Heinrich Wieland Prize of the Boehringer Ingelheim Foundation in Munich on November 6, 2015.

4 Nov 2015

Alnylam presents positive ongoing phase 2 open-label extension data for Patisiran and Revusiran

Alnylam Pharmaceuticals, Inc. has announced new results from its ongoing Phase 2 open-label extension (OLE) studies with patisiran and revusiran, investigational RNAi therapeutics targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR amyloidosis).

3 Nov 2015

Healthy food can help low-income people better control their diabetes

To determine whether healthy food could help low-income people better control their diabetes, a pilot study by UC San Francisco and Feeding America tracked nearly 700 people at food banks in California, Texas and Ohio over two years.

3 Nov 2015

Discovery offers promising alternative to current therapies for AMD and ROP

A research team led by scientists at Beth Israel Deaconess Medical Center and the University of New Mexico School of Medicine has identified a small molecule that treats animal models of aged macular degeneration (AMD) and retinopathy of prematurity (ROP) by preventing the overgrowth of blood vessels that are characteristic of these two retinal diseases.

3 Nov 2015

Charles Bonnet syndrome: an interview with Dr. Dominic ffytche

Charles Bonnet syndrome is the name we give to the visual hallucinations associated with eye disease. There are lots of different causes of visual hallucinations. Many different medical problems and medications can cause them, but, when the cause is eye disease, it's referred to as Charles Bonnet Syndrome after Charles Bonnet, who was a natural philosopher in the 18th century.

2 Nov 2015

Key protein controls stem cell properties that could make them useful in regenerative medicine

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.

31 Oct 2015

Prkci gene maintains balance in stem cell production

When it comes to stem cells, too much of a good thing isn't wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance of the body.

31 Oct 2015

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Scientists at the University of Cambridge have identified a new property of essential proteins which, when it malfunctions, can cause the build up, or 'aggregation', of misshaped proteins and lead to serious diseases.

31 Oct 2015

New online tool may allow researchers explore formation of hair follicles

A new online database will empower researchers exploring how hair follicles and the surrounding skin develop, according to an article published recently in the journal Developmental Cell. The work is central to understanding the interactions between stem cells and their environment - or "niche cells" - during fetal development, and will specifically facilitate future attempts to make skin grafts with functional hair follicles or to regenerate lost hair in patients.

30 Oct 2015

Findings could lead to new treatment for ALS, dementia

University of Toronto (U of T) researchers are proposing a new way of understanding Amyotrophic Lateral Sclerosis (ALS), the devastating and incurable neurological disease. Their findings, published today in the journal Neuron, could be a major milestone on the path to a treatment for both ALS and dementia.

30 Oct 2015

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Dementia specialists and PET imaging providers can now register to participate in the Imaging Dementia - Evidence for Amyloid Scanning (IDEAS) Study at Ideas-Study.org.

29 Oct 2015

Lund University researchers reveal how nerve cells learn and forget

Our brains not only contain learning mechanisms but also forgetting mechanisms that erase "unnecessary" learning. A research group at Lund University in Sweden has now been able to describe one of these mechanisms at the cellular level.

28 Oct 2015

Researchers compare effectiveness of combination therapy for black patients with asthma

Among black adults with asthma treated with an inhaled corticosteroid, adding a long-acting beta-agonist did not improve the time to an asthma exacerbation compared with adding the anticholinergic tiotropium, according to a study in the October 27 issue of JAMA.

28 Oct 2015

Motor proteins can stimulate growth of microtubules

Motor proteins that pause at the ends of microtubules and produce pushing forces can also stimulate their growth, according to researchers at Penn State. The proteins' function could be a critical component in understanding cell division and nerve branching and growth.

27 Oct 2015

Changes in lifestyle could reduce Alzheimer's disease risk

Changes in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University's Network Aging Research, who examined the data from two independent epidemiological studies. Carriers of the ApoE4 genetic risk factor for Alzheimer's may be able to reduce their increased risk of cognitive decline by reducing their cholesterol level, especially if they also suffer from cardiovascular disease.

27 Oct 2015

Maintaining normal BMI after pregnancy can help prevent pelvic organ prolapse

Maintaining a normal body mass index (BMI) is important for good cardiovascular health and blood sugar control, but maintaining it after pregnancy can also be key to preventing pelvic organ prolapse, according to a new study by Yale School of Medicine researchers.

27 Oct 2015

New Rice University study explores connections between fatal bereavement and cardiovascular risk

Medical professionals know that when a spouse dies, the surviving partner is at increased risk of suffering early mortality - but they don't entirely understand why. A new Rice University professor has received a $3.765 million R01 grant from the National Institutes of Health to embark on a five-year study of the connection between psychological and physiological responses to such extraordinary stress.

27 Oct 2015

Scientists decode central signal switch associated with epileptic seizures

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals.

27 Oct 2015

Hispanic, Medicaid patients less likely to receive regional anesthesia during hip and knee replacement surgery

Patients who are black, Hispanic, on Medicaid or are uninsured may be less likely to receive regional anesthesia during hip and knee replacement surgery, possibly putting them at greater risk of serious complications, according to a study of more than 1 million orthopedic surgeries being presented at the ANESTHESIOLOGY 2015 annual meeting.

26 Oct 2015

Nerve News and Research

Swedish measurement method to be used as standard in Alzheimer's diagnostics worldwide

Oxford professor wins Heinrich Wieland Prize for pioneering method that helps control nerve cells with light

Alnylam presents positive ongoing phase 2 open-label extension data for Patisiran and Revusiran

Healthy food can help low-income people better control their diabetes

Discovery offers promising alternative to current therapies for AMD and ROP

Charles Bonnet syndrome: an interview with Dr. Dominic ffytche

Key protein controls stem cell properties that could make them useful in regenerative medicine

Prkci gene maintains balance in stem cell production

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

New online tool may allow researchers explore formation of hair follicles

Findings could lead to new treatment for ALS, dementia

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Lund University researchers reveal how nerve cells learn and forget

Researchers compare effectiveness of combination therapy for black patients with asthma

Motor proteins can stimulate growth of microtubules

Changes in lifestyle could reduce Alzheimer's disease risk

Maintaining normal BMI after pregnancy can help prevent pelvic organ prolapse

New Rice University study explores connections between fatal bereavement and cardiovascular risk

Scientists decode central signal switch associated with epileptic seizures

Hispanic, Medicaid patients less likely to receive regional anesthesia during hip and knee replacement surgery

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