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CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup.

2 Jul 2014

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida.

2 Jul 2014

Study: Friends, parents, peers could influence young person's decision to drink walk

Friends may be the key to stopping their mates drink walking, a risky behaviour that kills on average two Australians every week, a QUT study has found.

1 Jul 2014

Report shows how negative health effects of noise can be reduced

Traffic noise is the second biggest environmental problem in the EU, according to WHO. After air pollution, noise is affecting health the most.

1 Jul 2014

Short sleep linked to cognitive decline in older adults

Researchers at Duke-NUS Graduate Medical School Singapore (Duke-NUS) have found evidence that the less older adults sleep, the faster their brains age.

1 Jul 2014

Study: Women's careers more likely to be disrupted by alcohol

John D. Meyer, MD, MPH, of Icahn-Mount Sinai School of Medicine, New York, and Miriam Mutambudzi, PhD, MPH, of Johns Hopkins School of Medicine, Baltimore, studied the relationship between occupation and AUDs in workers followed up from early adulthood to middle age.

1 Jul 2014

Metabolic pathway genes linked to AMD and choroidal vasculopathy

The cholesteryl ester transfer protein gene appears to increase susceptibility to neovascular age-related macular degeneration and polypoidal choroidal vasculopathy, research shows.

1 Jul 2014

Reticular drusen linked to AMD progression

Four percent of individuals aged 49 years and above will develop reticular drusen over 15 years of follow-up, Australian study findings suggest, with the incidence higher in those with age-related macular degeneration risk factors.

1 Jul 2014

Use of NMR in diagnostic research: an interview with Elaine Holmes, Imperial College

The Phenome Center developed out of the Olympic drug testing facility, and we've adapted it so that we use NMR spectrometry, which we have three spectrometers, and mass spectrometry, to take blood and urine from hundreds and thousands of people and profile them to get a biochemical fingerprint of every person.

From Bruker BioSpin Group 1 Jul 2014

Study: Lead in children's' blood linked to increased emotional and behavioral problems

Emotional and behavioral problems show up even with low exposure to lead, and as blood lead levels increase in children, so do the problems, according to research funded by the National Institute of Environmental Health Sciences, part of the National Institutes of Health. The results were published online June 30 in the journal JAMA Pediatrics.

1 Jul 2014

Vitamin D boost may prevent early death from heart disease and cancer

A vitamin D boost may prevent early death from heart disease and cancer, according to a large scale study by Mount Sinai and a consortium of international collaborators, published online in the June issue of BMJ.

1 Jul 2014

Genetic variants alter chance of sunitinib dose reduction

Scientists have identified genetic variants that reduce the likelihood of sunitinib dose reduction in patients with metastatic renal cell carcinoma.

30 Jun 2014

Sexting linked to sexual behavior in early adolescence

A study from USC researchers provides new understanding of the relationship between "sexting" and sexual behavior in early adolescence, contributing to an ongoing national conversation about whether sexually explicit text messaging is a risk behavior or just a technologically-enabled extension of normal teenage flirtation. The latest research, published in the July 2014 issue of the journal Pediatrics, found that among middle school students, those who reported receiving a sext were 6 times more likely to also report being sexually active.

30 Jun 2014

Modified classification system finds over one-third of knee replacements as inappropriate

New research reports that more than one third of total knee replacements in the U.S. were classified as "inappropriate" using a patient classification system developed and validated in Spain. The study, published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), highlights the need for consensus on patient selection criteria among U.S. medical professionals treating those with the potential need of knee replacement surgery.

30 Jun 2014

New less expensive method to enrich stable isotopes

Researchers at The University of Texas at Austin have devised a new method for enriching a group of the world's most expensive chemical commodities, stable isotopes, which are vital to medical imaging and nuclear power, as reported this week in the journal Nature Physics. For many isotopes, the new method is cheaper than existing methods. For others, it is more environmentally friendly.

30 Jun 2014

New estimates highlight the importance of developing norovirus vaccines

Noroviruses are a leading cause of acute gastroenteritis (diarrhoea and vomiting) across all age groups, responsible for almost a fifth (18%) of all cases worldwide. New estimates, published in The Lancet Infectious Diseases, highlight the importance of developing norovirus vaccines, say the authors.

28 Jun 2014

Kids’ familiarity with unhealthy food logos is linked to obesity

The more a child is familiar with logos and other images from fast-food restaurants, sodas and not-so-healthy snack food brands, the more likely the child is to be overweight or obese.

28 Jun 2014

Early life stress can have lasting negative impacts on the brain

For children, stress can go a long way. A little bit provides a platform for learning, adapting and coping. But a lot of it - chronic, toxic stress like poverty, neglect and physical abuse - can have lasting negative impacts.

28 Jun 2014

Menopause-related changes in sex hormones linked to greater risk for heart disease

As hormone levels change during the transition to menopause, the quality of a woman's cholesterol carriers degrades, leaving her at greater risk for heart disease, researchers at the University of Pittsburgh Graduate School of Public Health discovered.

28 Jun 2014

Researchers give new, unprecedented 3-D view of most important brain receptors

Researchers with Oregon Health & Science University's Vollum Institute have given science a new and unprecedented 3-D view of one of the most important receptors in the brain - a receptor that allows us to learn and remember, and whose dysfunction is involved in a wide range of neurological diseases and conditions, including Alzheimer's, Parkinson's, schizophrenia and depression.

28 Jun 2014