Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004

Patented fibrin-based matrices and tissue may open doors for tissue and organ engineering

Virginia Commonwealth University engineers and scientists have developed and patented a unique technique to grow three-dimensional tissues and organs in a mold made from material the human body naturally uses to repair wounds, potentially eliminating the chance for rejection.

17 Nov 2004

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Remember when Grandma used to say, "don’t go out in the cold; you’ll get sick”? It turns out that she was right for a small number of people who have a condition called familial cold autoinflammatory syndrome (FCAS)

16 Nov 2004

Safe, effective and reversible alternative contraceptives for men

Most men know when their family is complete, and vasectomy remains the most effective and safest form of sterilization. Around 10% of vasectomized men in the U.S desire vasectomy reversal due to the high divorce rate in this country and other life circumstances.

16 Nov 2004

Troponin genes offer new insights to familial heart failure

Mutations in the troponin protein complex may be useful for predicting the course of heart failure due to dilated cardiomyopathy and also for guiding treatment and research, according to a new study in the Nov. 16, 2004 issue of the Journal of the American College of Cardiology.

16 Nov 2004

Keeping fit lowers C-Reactive protein in people with metabolic syndrome

In people with signs of metabolic syndrome, including high blood pressure, high triglycerides, high cholesterol, elevated blood glucose and obesity, physical activity appears to reduce a marker for inflammation which has been linked to heart disease

16 Nov 2004

What makes beer taste so darn good to men, but vile to most women?

What makes beer taste so darn good to men, but vile to most women? Some oral sensations are under genetic control and new research suggests that these influences on taste perception could help determine the risk of excess alcohol consumption.

16 Nov 2004

Fluorescent protein tool may speed identification of molecular changes that reveal cells' inner workings

Scientists at Johns Hopkins and the University of Texas Medical Branch have created a new tool that easily reveals when and where a key cellular signal is active.

16 Nov 2004

Brain inflammation is a sign of autism

A new study by scientists at Johns Hopkins shows that brain inflammation is a sign of autism. The findings are reported in the online edition of Annals of Neurology, the scientific journal of the American Neurological Association.

15 Nov 2004

Vaccine provides new hope to the millions of people who suffer from food allergies

A team led by a researcher at the Stanford University School of Medicine has developed vaccines that vastly reduce or eliminate dogs' allergic reactions to three major food allergens: peanuts, milk and wheat. The vaccines' benefits lasted at least three months.

14 Nov 2004

Mast cells can provide protection from a potentially deadly condition known as sepsis

Mast cells are immune cells known mostly for their unwanted effects: they cause the wheezing of asthma, the itching of eczema, the sneezing and runny nose of hay fever and, in extreme cases, the life-threatening shock of anaphylaxis.

14 Nov 2004

Uncoupling proteins in the human heart

Results of a study in this week’s issue of THE LANCET suggest that respiratory uncoupling and reduced substrate availability might lead to energy deficiency in heart failure.

14 Nov 2004

Ireland is reporting its first case of variant Creutzfeldt-Jakob disease

The man in his early 20's was admitted to hospital as a suspected case 4 weeks ago. Recent tests on the patient's tonsils have detected the presence of the protein which causes vCJD.

11 Nov 2004

Important advance in understanding the structure of phage viruses

An important advance in understanding the structure of phage viruses, which infect and destroy bacteria, has been made by a team of scientists from Oxford and Finland, which could help develop new strategies to combat bacterial infections.

11 Nov 2004

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

The enzyme is known as PTPRO (for “protein tyrosine phosphatase receptor-type O”). When the gene responsible for producing PTPRO is silenced, as can happen in lung cancer, for example, the amount of the enzyme drops, allowing the cells to grow when they shouldn’t.

11 Nov 2004

New insight into how our body cells block the development of cancer

Scientists at the Medical Research Council (MRC) Cancer Cell Unit, at the University of Cambridge, have revealed a new insight into how our body cells block the development of cancer.

11 Nov 2004

Shp2 protein plays a critical role in obesity

A team of researchers led by The Burnham Institute's Gen-Sheng Feng, Ph.D. has discovered that a protein called Shp2 plays a critical role in obesity.

11 Nov 2004

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

The cholesterol-lowering drug atorvastatin slowed down mental decline and improved depressive symptoms in people with Alzheimer’s disease, according to a small pilot study reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

Results of a Phase II study of Abbott's ABT-874, a fully human anti-interleukin-12 (IL-12) monoclonal antibody, will appear tomorrow in the New England Journal of Medicine citing treatment with ABT-874 shows differences in response and remission in patients with active Crohn's disease compared to placebo, in one arm of the study.

10 Nov 2004

Metabolic syndrome associated with cognitive decline in elderly persons

Elderly individuals with the metabolic syndrome, a grouping of several common conditions including abdominal obesity, low level of high-density lipoprotein (HDL, the “good cholesterol”), hypertension, and high triglyceride and blood sugar levels, are more likely to experience cognitive impairment than those without this syndrome, according to a study in the November 10 issue of JAMA.

10 Nov 2004

Protein News and Research

Further Reading

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Patented fibrin-based matrices and tissue may open doors for tissue and organ engineering

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Safe, effective and reversible alternative contraceptives for men

Troponin genes offer new insights to familial heart failure

Keeping fit lowers C-Reactive protein in people with metabolic syndrome

What makes beer taste so darn good to men, but vile to most women?

Fluorescent protein tool may speed identification of molecular changes that reveal cells' inner workings

Brain inflammation is a sign of autism

Vaccine provides new hope to the millions of people who suffer from food allergies

Mast cells can provide protection from a potentially deadly condition known as sepsis

Uncoupling proteins in the human heart

Ireland is reporting its first case of variant Creutzfeldt-Jakob disease

Important advance in understanding the structure of phage viruses

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

New insight into how our body cells block the development of cancer

Shp2 protein plays a critical role in obesity

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

Metabolic syndrome associated with cognitive decline in elderly persons

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