Therapy News and Research

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New drug target for treatment-resistant prostate cancer

Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have found that a signaling protein that is key to prostate cancer cell growth is turned on in nearly all recurrent prostate cancers that are resistant to hormone therapy.

2 Jan 2008

Drug effective for hepatitis C patients with low platelets

For patients with hepatitis C, having a low blood platelet count is a frequent complication associated with advanced disease.

2 Jan 2008

New clinical practice recommendations to help health care providers treat people with diabetes

The American Diabetes Association (ADA) has issued its annual Clinical Practice Recommendations to help health care providers treat people with diabetes using the most current evidence available.

2 Jan 2008

Study shows that antiangiogenic agent delays progression of advanced breast cancer

The positive results of the first nationwide clinical study showing the benefits of an antiangiogenic agent in breast cancer therapy are reported in the Dec. 27 issue of the New England Journal of Medicine.

28 Dec 2007

Help for musician's dystonia

Therapy that stimulates the hand muscles may help treat the condition called musician's dystonia, a movement disorder that causes muscles spasms in musicians, according to a study published in the December 26, 2007, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Dec 2007

Patient with AIDS finds heart-assit device is an option when transplant is not

Josh Bristow was in the late stages of heart failure when he came to the Emergency Department at Cedars-Sinai Medical Center on Aug. 25, 2007.

28 Dec 2007

NIEHS awards $6.8 million DISCOVER grants

The National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, is awarding a total of $6.8 million for the first year of funding to three new research centers called DISCOVER - Disease Investigation Through Specialized Clinically-Oriented Ventures in Environmental Research.

28 Dec 2007

Light powered platinum more targeted and powerful than similar cancer treatments

Researchers from the Universities of Warwick, Edinburgh, Dundee and the Czech Republic's Institute of Biophysics have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light activation" to kill cancer cells in much more targeted way than similar treatments.

28 Dec 2007

Optimal therapy for U.S. hepatitis C patients

As reported recently in the journal Hepatology, WIN-R, a multicenter study of over 5,000 patients with hepatitis C virus (HCV) showed treatment with weight-based REBETOL ribavirin, USP) (RBV) in combination with pegylated interferon (PEG-IFN) alfa-2b achieved significantly higher rates of sustained virologic response (SVR) and lower relapse rates compared to combination therapy using a flat dose of RBV 800 mg/day. Superior response was found particularly in patients with the most difficult-to-treat form of the disease, genotype 1 HCV. Efficacy was consistent across all weight groups.

28 Dec 2007

Fibrosis in the liver stopped and reversed by researchers

University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed.

28 Dec 2007

Variant of COMT gene linked to impulsive decisions

People with clinical addictions know first-hand the ravages the disease can take on almost every aspect of their lives.

28 Dec 2007

Cell-death receptor links cancer susceptibility and inflammation

For over 10 years, Wafik S. El-Deiry, MD, PhD, Professor of Medicine, Genetics, and Pharmacology at the University of Pennsylvania School of Medicine, has been pursuing a cancer-targeting molecule called TRAIL and its molecular partners.

28 Dec 2007

Cardiac stem cell therapy research

Since the year 2000, much has been learned about the potential for using transplanted cells in therapeutic efforts to treat varieties of cardiac disorders.

28 Dec 2007

Brain imaging shows there may be a cognitive difference in people with addictions

Scientists have for the first time identified brain sites that fire up more when people make impulsive decisions.

28 Dec 2007

Bevacizumab found to improve survival for patients with advanced breast cancer

Inhibiting the growth of blood vessels that supply tumors slows the progression of metastatic breast cancer according to results of a large clinical trial of Avastin, an anti-angiogenic therapy.

28 Dec 2007

Tweaking a gene may fix Fragile X syndrome

According to new research clues to Fragile X syndrome may be connected to one single human gene.

20 Dec 2007

Advanced melanoma - new treatment

University of Illinois at Chicago researchers are participating in a multi-center research trial to evaluate the safety and effectiveness of Allovectin-7, an investigational treatment for advanced melanoma.

20 Dec 2007

Study examines computed tomographic pulmonary angiography for diagnosing blood clots in the lung

New research indicates that a diagnostic strategy using computed tomographic pulmonary angiography (CTPA) may be a safe alternative to conventional lungs scans (known as ventilation-perfusion scans) for excluding the diagnosis of pulmonary embolism (blood clots in the lung vessels), although CTPA may detect more clots, according to a study in the current issue of JAMA: The Journal of the American Medical Association.

20 Dec 2007

Simple measures to control spread of XDR TB

By using a combination of inexpensive infection control measures, hospitals around the world could prevent half the new cases of extensively drug resistant tuberculosis (XDR TB), according to a new study in The Lancet by researchers at Yale School of Medicine.

20 Dec 2007

Safer, more accurate, and more effective radiation therapy for pregnant women

Developing fetuses are extremely sensitive to radiation, which poses an impossible dilemma for expecting mothers in need of screening or treatment for cancer.

20 Dec 2007