Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

The microorganisms that normally live in the gut can increase body fat

The microorganisms that normally live in the gut can increase body fat, say researchers at Washington University School of Medicine in St. Louis. They found that gut microbes can open the "gates" fat uses to enter the body's fat cells.

1 Nov 2004

New approaches for the treatment of chronic hepatitis C

Data from two ongoing studies testing new approaches for the treatment of chronic hepatitis C was presented at the annual meeting of the American Association for the Study of Liver Diseases (AASLD) this afternoon.

1 Nov 2004

Diabetic or obese patients suffering advanced heart failure have higher levels of fat embedded in their hearts

Heart failure, progressive and potentially fatal weakening of the heart muscle, is associated with both obesity and diabetes, but the mechanisms by which damage occurs are not well-understood, said senior author Heinrich Taegtmeyer, M.D., Ph.D., professor of cardiology.

1 Nov 2004

Protein important to nerve development serves the dual purpose of stimulating the growth of blood vessels

The discovery opens the possibility that blood vessel growth (angiogenesis) one day may be induced, or stymied, for therapeutic use against heart disease, cancer, and other illnesses, according to Dean Y. Li, M.D., Ph.D., associate professor of internal medicine in the U of U School of Medicine's Division of Cardiology.

1 Nov 2004

Cigarette smoking can dramatically affect appetite and weight control

The study by researchers in the Department of Pharmacology and the CRC for Chronic Inflammatory Diseases found that mice exposed to four days of cigarette smoke displayed significant loss of appetite, fat tissue and body weight.

1 Nov 2004

First home-testing device for phenylketonuria (PKU) patients

Home-testing kits have made it easier for diabetics and hypertension patients to track their conditions, but such self-monitoring hasn’t been possible for people with phenylketonuria (PKU).

1 Nov 2004

Interim recommendations on low-carb diets

From the extreme Atkins Diet to the more modest Zone Diet, low carbohydrate diets are all the rage, embraced by celebrities and the general public alike as a quick way to lose weight.

1 Nov 2004

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

A research team led by University of South Florida neuroscientist Huntington Potter, PhD, CEO of the Johnnie B. Byrd Sr. Alzheimer's Center & Research Institute, for the first time has defined how the protein Apolipoprotein E (ApoE) contributes to both the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease.

1 Nov 2004

Gene silencing may provide hope for leukemia sufferers

Ever since the approval of Gleevec in 2001, a cancer-cell-specific drug used to treat chronic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called "targeted" medicines.

1 Nov 2004

Cellular enzyme represents a potential new target for developing improved HIV drugs

Scientists have discovered that a cellular enzyme helps ferry HIV genetic instructions out of the cell nucleus where they can then be translated into proteins to begin their most destructive work.

1 Nov 2004

New role for a key protein involved in muscle contraction

Overturning a scientific stereotype, researchers at the University of Illinois at Chicago have discovered a new role for a key protein involved in muscle contraction and shown it is present not just in the cytoplasm of cells but in the nucleus as well.

1 Nov 2004

Patients are receiving initial diagnosis of celiac disease at an older age

Patients are receiving initial diagnosis of celiac disease at an older age and with a shorter duration of symptoms, according to a retrospective study presented today at the 69th Annual Scientific Meeting of the American College of Gastroenterology.

1 Nov 2004

Scientists have found that a protein present in normal body tissues can prevent tumour growth

A team led by Dr Dave Bates, British Heart Foundation Lecturer, and Dr Steve Harper, Senior Research Fellow in the Microvascular Research Laboratories, in the Department of Physiology at Bristol University, have discovered that a type of vascular endothelial growth factor (VEGF) found in normal tissue, including blood, can prevent cancers from growing.

1 Nov 2004

Interaction of nervous system proteins help researchers better understand age-related memory and hearing loss

In a finding that may one day help researchers better understand age-related memory and hearing loss, scientists have shown that two key nervous system proteins interact in a manner that helps regulate the transmission of signals in the nervous system.

29 Oct 2004

Genetic evidence to support an inherited tendency to retain salt

Researchers at the University of Chicago have found genetic evidence to support the sodium-retention hypothesis, a controversial 30-year-old theory that the high rate of hypertension in certain ethnic groups is caused, in part, by an inherited tendency to retain salt.

29 Oct 2004

Red wine delivered though an aerosol for COPD, asthma, and possibly even arthritis

Homing in on mechanisms for the reported effectiveness of resveratrol, which is found in red wine, researchers at Imperial College London, England, confirmed its broad anti-inflammatory action, and found potential for applications in chronic obstructive pulmonary disease (COPD), asthma, and possibly even arthritis.

29 Oct 2004

Trojan horse technique offers potential new therapeutic approach to Alzheimer's disease

A potential new therapeutic approach to Alzheimer's disease protects brain cells in culture by drastically reducing the neurotoxic amyloid protein aggregates that are critical to the development of the disease.

29 Oct 2004

Scientists have uncovered a significant new link in the chain of immune system events through which estrogen prevents bone loss

Through research in mice, the scientists discovered that an immune signaling molecule called type b transforming growth factor (TGFb) is responsible for a cascade of events that leads estrogen to prevent bone loss.

29 Oct 2004

Study supports earlier findings, and even showed a significantly higher prevalence of periodontal diseases in cardiac patients

Research is racing to help healthcare professionals further understand how periodontal diseases are linked to cardiovascular disease.

28 Oct 2004

New insights into hormone therapy show when estrogen best aids brain

New hormone therapy studies demonstrate estrogen's ability to directly stimulate neurons, repair damaged neurons, and stimulate support cells—most of which can alleviate some of the cognitive decline associated with menopause.

28 Oct 2004

Protein News and Research

Further Reading

The microorganisms that normally live in the gut can increase body fat

New approaches for the treatment of chronic hepatitis C

Diabetic or obese patients suffering advanced heart failure have higher levels of fat embedded in their hearts

Protein important to nerve development serves the dual purpose of stimulating the growth of blood vessels

Cigarette smoking can dramatically affect appetite and weight control

First home-testing device for phenylketonuria (PKU) patients

Interim recommendations on low-carb diets

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

Gene silencing may provide hope for leukemia sufferers

Cellular enzyme represents a potential new target for developing improved HIV drugs

New role for a key protein involved in muscle contraction

Patients are receiving initial diagnosis of celiac disease at an older age

Scientists have found that a protein present in normal body tissues can prevent tumour growth

Interaction of nervous system proteins help researchers better understand age-related memory and hearing loss

Genetic evidence to support an inherited tendency to retain salt

Red wine delivered though an aerosol for COPD, asthma, and possibly even arthritis

Trojan horse technique offers potential new therapeutic approach to Alzheimer's disease

Scientists have uncovered a significant new link in the chain of immune system events through which estrogen prevents bone loss

Study supports earlier findings, and even showed a significantly higher prevalence of periodontal diseases in cardiac patients

New insights into hormone therapy show when estrogen best aids brain

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