Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Molecule that helps DNA replicate may make good target for cancer therapy

In order to divide, cells must first replicate their chromosomes. Cells use an array of proteins to accomplish the job, including a large enzyme complex that synthesizes new strands of DNA.

21 Oct 2004

Discovery of the gene for a form of Joubert Syndrome

Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered the gene for a form of Joubert Syndrome, a condition present before birth that affects an area of the brain controlling balance and coordination in about 1 in 10,000 individuals.

21 Oct 2004

Researchers trim count of human genes to 20,000-25,000

Scientific description of the finished human genome sequence, reducing the estimated number of human protein-coding genes from 35,000 to only 20,000-25,000, a surprisingly low number for our species.

21 Oct 2004

Gene variations explain why people with type 2 diabetes are at much greater risk for coronary artery disease

New studies by an international team of scientists led by Joslin Diabetes Center have found variations in a gene that help explain why people with type 2 diabetes are at much greater risk for coronary artery disease, the leading cause of death for this group.

21 Oct 2004

Atypical antipsychotics commonly used to treat children with aggression, bipolar disorder, and schizophrenia may trigger insulin resistance

Researchers from the Johns Hopkins Children's Center say a group of drugs known as "atypical antipsychotics" that are commonly used to treat children with aggression, bipolar disorder, and schizophrenia may trigger insulin resistance, a condition that increases the risk of developing Type 2 diabetes and heart disease later in life.

21 Oct 2004

Genetic research offers insight into Sjögren's syndrome and the general developmental machinery of the immune system

By knocking out a single gene in mice, immunologists at Duke University Medical Center have mimicked a little-understood autoimmune disorder in humans.

21 Oct 2004

Common antibacterial and antifungal ingredient used in tooth paste may protect against skin cancer

According to new studies, sanguinarine was shown to enhance production of proteins that induce cell death, or apoptosis, in cells damaged by ultraviolet-B (UVB) radiation.

21 Oct 2004

Researchers identify a protein that could banish allergies

The suffering of millions of people with allergies could one day be eased thanks to new research from UK investigators. Findings from the University College London branch of the Ludwig Institute for Cancer Research (LICR), published in the Oct 2004 issue of Nature, detail how inactivating a key signalling molecule called p110delta reduced the effect of allergies on mice.

21 Oct 2004

Organic molecules spontaneously organize themselves into large spherical structures

A critical step in the emergence of life was the spontaneous self-organization of identical small units into large symmetrical structures.

21 Oct 2004

Babies born by Caesarean section may be at greater risk of diarrhoea

Babies born by Caesarean section may be at greater risk of diarrhoea and sensitisation to certain foodstuffs during their first 12 months than babies born vaginally, suggests research in the Archives of Disease in Childhood.

21 Oct 2004

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Brain cells become increasingly unable to regulate calcium loads as they age, becoming more vulnerable to injury and premature death, according to new findings that Virginia Commonwealth University researchers will present at an international conference this month.

20 Oct 2004

Researchers are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes

Researchers at UT Southwestern Medical Center at Dallas are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes.

19 Oct 2004

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

A brain protein already known to play a central role in the "feast or fast" signaling that controls the urge to eat has now been found to influence appetite in a second way. The discovery identifies a potential new target for drugs against obesity.

19 Oct 2004

Scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia

UCLA scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia, (A-T), a life-shortening disorder that devastates the neurological and immune systems of one in 40,000 young children.

19 Oct 2004

Discovery might improve design, effectiveness of anti-cancer drugs

Working with an enzyme that degrades anti-cancer drugs in humans, University of North Carolina at Chapel Hill biochemists and colleagues have made a discovery that they believe eventually could help improve such drugs’ design and effectiveness.

18 Oct 2004

QIMR researchers have received a 5 year grant to develop a vaccine against Group A streptococcus

QIMR researchers have received a 5 year grant from the National Institutes of Health in the USA to develop a vaccine against Group A streptococcus. This extremely prestigious grant makes QIMR one of the most successful recipients of NIH funding in Australia.

18 Oct 2004

Cyclopamine, derived from the corn lily may treat and prevent basal cell carcinoma

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have demonstrated in laboratory animals that a compound derived from a common plant can be used to treat and prevent the most widespread form of cancer in people

18 Oct 2004

New treatment antibody - AMG 162 - may help prevent osteoporosis and rheumatoid arthritis

A novel treatment administered semiannually to postmenopausal women with low bone density appears to rapidly inhibit the bone resorption process, resulting in improvements in bone mineral density at 12 months

18 Oct 2004

Researchers have developed a novel drug-antidote pair

In a discovery that could give physicians more control over the actions of medications, researchers at Duke University Medical Center have developed a novel drug pair – a potent anti-coagulant with a matched "antidote."

18 Oct 2004

Malaria vaccine candidate looks extremely promising

In a proof-of-concept study published this week in The Lancet, researchers report that GlaxoSmithKline's RTS,S/AS02A malaria vaccine candidate protected a significant percentage of children against uncomplicated malaria, infection, and even severe forms of the disease for at least six months.

16 Oct 2004

Protein News and Research

Further Reading

Molecule that helps DNA replicate may make good target for cancer therapy

Discovery of the gene for a form of Joubert Syndrome

Researchers trim count of human genes to 20,000-25,000

Gene variations explain why people with type 2 diabetes are at much greater risk for coronary artery disease

Atypical antipsychotics commonly used to treat children with aggression, bipolar disorder, and schizophrenia may trigger insulin resistance

Genetic research offers insight into Sjögren's syndrome and the general developmental machinery of the immune system

Common antibacterial and antifungal ingredient used in tooth paste may protect against skin cancer

Researchers identify a protein that could banish allergies

Organic molecules spontaneously organize themselves into large spherical structures

Babies born by Caesarean section may be at greater risk of diarrhoea

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Researchers are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

Scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia

Discovery might improve design, effectiveness of anti-cancer drugs

QIMR researchers have received a 5 year grant to develop a vaccine against Group A streptococcus

Cyclopamine, derived from the corn lily may treat and prevent basal cell carcinoma

New treatment antibody - AMG 162 - may help prevent osteoporosis and rheumatoid arthritis

Researchers have developed a novel drug-antidote pair

Malaria vaccine candidate looks extremely promising

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