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Bionovo describes a new class of therapeutic compounds

Bionovo, Inc. has announced the publication of a groundbreaking paper in the journal Molecular and Cellular Endocrinology covering the isolation, identification and description of a pure chemical compound, liquiritigenin, which represents a new class of therapeutic compounds showing promise for the safe treatment of menopausal symptoms.

2 Dec 2007

AstraZeneca receives six months pediatric exclusivity patent extension for ARIMIDEX (anastrozole)

AstraZeneca has announced that the United States (US) Food and Drug Administration (FDA) has granted an additional six-month period of exclusivity to market ARIMIDEX (anastrozole) for its licensed breast cancer indications until June 2010.

2 Dec 2007

Altered sex hormone levels, higher body temp affects sleep quality in postmenopausal women

In an examination of potential relationships between objective sleep measures, nocturnal sex hormone levels, and the nocturnal course of body temperature of older postmenopausal women, a study published in the December 1, 2007 issue of the journal SLEEP finds that altered levels of both sex hormones and gonadotropins may contribute to sleep disturbance in older postmenopausal women and confirm the results of previous studies indicating that higher body temperature is associated with poorer sleep quality.

2 Dec 2007

Queen's University Belfast opens new centre for cancer research

Queen's Chancellor Senator George Mitchell officially opened the University's new £25M cancer research centre aimed at stopping the spread of cancer.

29 Nov 2007

Pneumococcal conjugate vaccines can improve the lives of HIV-infected children

An international team of experts has published the first comprehensive review of evidence on pneumococcal conjugate vaccination (PCV) for children with HIV infection.

29 Nov 2007

Occupational therapy is effective in improving independence in stroke patients

Occupational therapy can improve the lives of patients who have suffered a stroke and lessen their chances of deteriorating or even dying, according to an international study published in the British Medical Journal Online.

29 Nov 2007

New minimally invasive procedure to treat tendonitis in the shoulder

Ultrasound-guided non-surgical therapy significantly reduces pain from calcific tendonitis of the rotator cuff and restores mobility, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).

29 Nov 2007

Scientists observe gene activity outside the body

Researchers at Jefferson Medical College and Jefferson's Kimmel Cancer Center in Philadelphia have used PET imaging to see hyperactive cancer genes inside breast tumors in laboratory animals, marking the first time such gene activity has been observed from outside the body.

29 Nov 2007

Genetic selection of target stem cell populations

Human embryonic stem cells can be genetically manipulated to help select out desirable cell types, according to a University of Nottingham study published online in Molecular Therapy.

29 Nov 2007

Effects of weight, genetics and religious beliefs on prostate cancer

African-American men face an observable disadvantage versus Caucasian men when it comes to prostate cancer survival.

29 Nov 2007

Discovery of link between moderate exercise and decreased inflammation of damaged skin tissue

In recent years, researchers at the University of Illinois have uncovered a host of reasons for people to remain physically active as they age, ranging from better brain function to improved immune responses.

29 Nov 2007

Eltrombopag studied in Idiopathic Thrombocytopenic Purpura

There are estimated to be between 50,000 -- 100,000 individuals in the U.S. diagnosed with chronic Immune Thrombocytopenic Purpura (ITP), an autoimmune disease that dramatically reduces the number of platelets in their blood -- causing bruises, nosebleeds and, sometimes, life-threatening brain hemorrhages.

29 Nov 2007

Could stem cells be used to cure Crohn's Disease?

Scientists are investigating whether stem cells could be used to 're-boot' the immune system and provide a cure for Crohn's Disease.

29 Nov 2007

Researchers find evidence of mature heart cell potential in embryonic stem cells

In a new study, UC Davis researchers report the first functional evidence that heart cells derived from human embryonic stem cells exhibit one of the most critical properties of mature adult heart cells, an important biological process called excitation-contraction coupling.

27 Nov 2007

Stem cells train heart following heart attack

Following a heart attack, part of the heart tissue dies. It is still not possible to restore the scar tissue arising as a result of this. The majority of stem cell researchers attempt to make new heart muscle cells from stem cells.

27 Nov 2007

HIV in Thailand appears more deadly

Two studies led by researchers at the Johns Hopkins Bloomberg School of Public Health found that people infected with HIV in Thailand die from the disease significantly sooner than those with HIV living in other parts of the world.

27 Nov 2007

Researchers outline structure of largest nonvirus particle ever crystallized

Researchers at UCLA's California NanoSystems Institute, the David Geffen School of Medicine at UCLA and the Howard Hughes Medical Institute have modeled the structure of the largest cellular particle ever crystallized, suggesting ways to engineer the particles for drug delivery.

27 Nov 2007

RNA polymerase III mutation disrupts organ growth

The cellular mechanism that turns DNA into all of the thousands of proteins that make up a human body is itself both intricate and interesting.

27 Nov 2007

MIT radar technology fights breast cancer

Treating breast cancer with a type of heat therapy derived from MIT radar research can significantly increase the effectiveness of chemotherapy, according to results from the fourth clinical trial of the technique reported online Nov. 25 in the journal Cancer Therapy.

27 Nov 2007