Malignant News and Research

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Mouse model for human malignant mesothelioma

Scientists have established a mouse model for human malignant mesothelioma (MM) that will provide valuable insight into cancer development and progression along with new directions for design of therapeutic strategies.

11 Mar 2008

Better management of ovarian cancer

The results of a study presented at the Society of Gynecologic Oncology's 39th Annual Meeting on Women's Cancer offer a promising development on the path toward better management of ovarian cancer.

11 Mar 2008

Gardasil reduces abnormal Pap test results

A significant drop in abnormal Pap test results happened after girls and women were given a vaccine to prevent cervical cancer, according to a researcher at the University of Alabama at Birmingham (UAB).

10 Mar 2008

Older adults also using the tanning salon

Think you won't run into grandparents at your local tanning salon? According to new research, you just might. In fact, a recent health survey of American adults suggests that while 20 percent of 18-39 year olds visited tanning beds, as many as 10 percent of those between 50 and 64 years of age and eight percent of those older than 65 tanned indoors.

10 Mar 2008

Curing cancer with natural products - a case for shamans and herb women?

Not at all, for many chemotherapies to fight cancer applied in modern medicine are natural products or were developed on the basis of natural substances. Thus, taxanes used in prostate and breast cancer treatment are made from yew trees. The popular periwinkle plant, which grows along the ground of many front yards, is the source of vinca alkaloids that are effective, for example, against malignant lymphomas. The modern anti-cancer drugs topotecan and irinotecan are derived from a constituent of the Chinese Happy Tree.

6 Mar 2008

Protein in embryonic stem cells control malignant tumor cells

A protein that governs development of human embryonic stem cells (hESCs) also inhibits the growth and spread of malignant melanoma, the deadliest skin cancer, Northwestern University researchers have discovered.

4 Mar 2008

New nanotube findings give boost to potential biomedical applications

Carbon nanotubes have shown real promise as highly accurate vehicles for delivering antitumor agents into malignant cells, but a dearth of data about what happens to the tubes after they discharge their medical payloads has been a major stumbling block to progress.

3 Mar 2008

Nanotechnology advances brain cancer detection and therapy

Brain cancer is one of the most aggressive and lethal of malignancies, made even more difficult to treat by the fact that most anticancer drugs have a hard time even getting to the tumors.

3 Mar 2008

Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells

Early detection of tumors is one of the Holy Grails of cancer research, an achievement that would greatly improve cancer therapy and prognosis. Two new reports describe different but promising approaches to solving this problem.

3 Mar 2008

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for once- daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of major depressive disorder (MDD) as monotherapy, adjunct therapy, and maintenance therapy in adult patients.

1 Mar 2008

Stress and fear affects cancer's recurrence

After the surgical removal of a malignant tumor, the chance that cancer will re-appear in a different location of the body remains high.

28 Feb 2008

ImClone Systems enrols first patient in clinical trial of IMC-1121B to treat liver cancer

ImClone Systems Incorporated has announced that it has enrolled the first patient in a disease-directed Phase II clinical trial of IMC-1121B to treat patients with advanced hepatocellular carcinoma (liver cancer).

26 Feb 2008

Brain tumour gene link found

Cancer Research UK funded scientists have discovered a mutation in a DNA repair gene which may increase the risk of developing meningioma , a rare type of brain tumour , according to new research published in the latest edition of the Journal of the National Cancer Institute .

26 Feb 2008

Are tumors causing stricture of bile duct always malignant?

The benign biliary tract tumor is rarely found in clinical practice.

26 Feb 2008

Tumor blood vessels can develop from precancerous stem cells

Tumors require a blood supply to grow, but how they acquire their network of blood vessels is poorly understood.

20 Feb 2008

Ocular melanoma - potential new treatment options

Ocular melanoma is rarely detected before it has grown large enough to impair vision or to metastasize.

20 Feb 2008

Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors

Researchers in a multi-institutional study led by Cincinnati Children's Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers - neuroblastoma and peripheral nerve sheath tumors - without harming healthy tissues by inserting instructions to inhibit tissue growth into an engineered virus, according to study results published in the February 15 Cancer Research.

18 Feb 2008

Complex fibroadenomas patients can avoid surgery

Complex fibroadenomas have a low incidence of malignancy, so women with this condition can be more conservatively treated and avoid surgical biopsy, according to a new study by a team of researchers from the Hadassah-Hebrew University Medical Center in Jerusalem.

12 Feb 2008

PET outperforms CT in characterization of lung nodules

Researchers involved in a large, multi-institutional study comparing the accuracy of positron emission tomography (PET) and computed tomography (CT) in the characterization of lung nodules found that PET was far more reliable in detecting whether or not a nodule was malignant.

7 Feb 2008

Early detection of pediatric thyroid cancer critical

Efforts to treat pediatric papillary thyroid cancer are greatly improved by detecting the disease as early as possible, making the patient's age the most important factor in determining a prognosis, according to new research published in the February 2008 issue of the journal Otolaryngology Head and Neck Surgery.

5 Feb 2008