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Small heat shock protein as model for Alzheimer’s medication

In Alzheimer’s disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München have now uncovered how the protein interacts with other proteins.

13 Oct 2015

IU investigators find how cancer-induced bone destruction triggers skeletal muscle weakness

Cancer researchers at Indiana University and their colleagues have discovered how cancer-induced bone destruction causes skeletal muscle weakness.

12 Oct 2015

New clinical study focuses on investigational treatment to reduce impact of key protein from the brain

The Nantz National Alzheimer Center at Houston Methodist Hospital is part of a landmark clinical trial that looks at removing a key protein from the brain to prevent memory loss at least a decade before symptoms are noticed in healthy older adults.

12 Oct 2015

Pioneering surgical technique restores hand and arm movement to quadriplegic patients

A pioneering surgical technique has restored some hand and arm movement to patients immobilized by spinal cord injuries in the neck, reports a new study at Washington University School of Medicine in St. Louis.

12 Oct 2015

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Chronic pain results from disease or trauma to the nervous system. Damaged nerve fibres with heightened responses to normal stimuli send incorrect messages to pain centres in the brain. This phenomenon, called "peripheral and central sensitization" is one of the key mechanisms involved in the condition which touches people with diabetes, cancer, and those suffering from multiple sclerosis, among others.

12 Oct 2015

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS). This is the first demonstration that introduction of blood in the healthy brain is sufficient to cause peripheral immune cells to enter the brain, which then go on to cause brain damage.

12 Oct 2015

Scientists can now use skin samples from older patients to grow brain cells

For the first time, scientists can use skin samples from older patients to create brain cells without rolling back the youthfulness clock in the cells first. The new technique, which yields cells resembling those found in older people's brains, will be a boon to scientists studying age-related diseases like Alzheimer's and Parkinson's.

9 Oct 2015

Gene therapy prevents neuronal death, disease effects in experimental model of PD

An estimated seven to ten million people worldwide are living with Parkinson's disease (PD), which is an incurable and progressive disease of the nervous system affecting movement and cognitive function. More than half of PD patients develop progressive disease showing signs of dementia similar to Alzheimer's disease.

9 Oct 2015

Research shows sex change hormonal treatment also changes brain chemistry

Hormonal treatments administered as part of the procedures for sex reassignment have well-known and well-documented effects on the secondary sexual characteristics of the adult body, shifting a recipient's physical appearance to that of the opposite sex.

9 Oct 2015

Tresiba and Ryzodeg approved to improve blood sugar control in adults with diabetes mellitus

The U.S. Food and Drug Administration today approved Tresiba (insulin degludec injection) and Ryzodeg 70/30 (insulin degludec/insulin aspart injection) to improve blood sugar (glucose) control in adults with diabetes mellitus.

9 Oct 2015

Bankers Healthcare Group's company-wide diabetes awareness campaign to run through November

Bankers Healthcare Group, the leading provider of financial solutions for healthcare professionals, recently launched a company-wide diabetes awareness campaign that will run through November.

8 Oct 2015

Lund researchers one step closer to developing implantable electrodes for capturing brain function

For nearly nine years, researchers at Lund University have been working on developing implantable electrodes that can capture signals from single neurons in the brain over a long period of time - without causing brain tissue damage. They are now one big step closer to reaching this goal, and the results are published in the scientific journal Frontiers in Neuroscience.

8 Oct 2015

NYIT's Aydin Farajidavar receives NIH grant to develop implantable wireless device for measuring gastric activity

New York Institute of Technology Assistant Professor Aydin Farajidavar has received a $457,000 National Institutes of Health grant to develop an implantable wireless system to study the body's gastric and digestive systems.

8 Oct 2015

Use of chest CT scans for hospital emergency-room patients with blunt trauma can be reduced: Study

Use of computed tomography (CT) scans of the chest for hospital emergency-room patients with blunt trauma could be reduced by more than one-third without compromising detection of major injury, concludes a new study led by a UC San Francisco physician.

7 Oct 2015

NIH researchers discover why certain immune responses can be harmful to the brain

National Institutes of Health scientists studying inflammation of the brain have discovered why certain immune responses, which typically help cells recognize and fight viral and bacterial infections, can sometimes be harmful to the brain. Many brain disorders involve the death of neurons, or nerve cells, but how these neurons die is not well understood.

7 Oct 2015

Dopamine transmission mediated by D1 receptors essential for controlling movements in Parkinson's disease

Dopamine deficiency in the basal ganglia (a set of subcortical structures) causes severe motor dysfunctions, such as slowness of movements (bradykinesia), as observed in Parkinson's disease. Dopamine binds D1 and D2 receptors that are expressed in the nerve cells of the striatum (a structure of the basal ganglia), and exerts different effects on the nerve cells. However, how dopamine controls through these receptors the information flow in the basal ganglia and voluntary movements is still not clear.

6 Oct 2015

NIH-funded researchers test new gene therapy to improve visual function in mice

Researchers funded by the National Institutes of Health have developed a novel mouse model for the vision disorder Leber hereditary optic neuropathy (LHON), and found that they can use gene therapy to improve visual function in the mice. LHON is one of many diseases tied to gene mutations that damage the tiny energy factories that power our cells, called mitochondria.

6 Oct 2015

Neuron firing patterns in IT cortex linked with object-recognition tasks

When the eyes are open, visual information flows from the retina through the optic nerve and into the brain, which assembles this raw information into objects and scenes.

6 Oct 2015

Songbirds may help researchers find cure for Huntington’s disease

Many neurological disorders can rob someone of the ability to speak clearly, causing them to stutter, mispronounce words, and struggle to put together coherent sentences. However, the molecular and neurological dysfunctions that cause these symptoms aren't well understood. Recent work at The Rockefeller University may give researchers a new tool to better study these vocal and speech impairments, particularly in Huntington's disease.

6 Oct 2015

Experimental drug shows promise in mice with multiple sclerosis

An experimental drug originally identified in a National Cancer Institute library of chemical compounds as a potential therapy for brain and basal cell cancers improves the symptoms of mice with a form of the debilitating neurological disorder multiple sclerosis (MS), according to new research from NYU Langone Medical Center.

1 Oct 2015

Nerve News and Research

Small heat shock protein as model for Alzheimer’s medication

IU investigators find how cancer-induced bone destruction triggers skeletal muscle weakness

New clinical study focuses on investigational treatment to reduce impact of key protein from the brain

Pioneering surgical technique restores hand and arm movement to quadriplegic patients

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

Scientists can now use skin samples from older patients to grow brain cells

Gene therapy prevents neuronal death, disease effects in experimental model of PD

Research shows sex change hormonal treatment also changes brain chemistry

Tresiba and Ryzodeg approved to improve blood sugar control in adults with diabetes mellitus

Bankers Healthcare Group's company-wide diabetes awareness campaign to run through November

Lund researchers one step closer to developing implantable electrodes for capturing brain function

NYIT's Aydin Farajidavar receives NIH grant to develop implantable wireless device for measuring gastric activity

Use of chest CT scans for hospital emergency-room patients with blunt trauma can be reduced: Study

NIH researchers discover why certain immune responses can be harmful to the brain

Dopamine transmission mediated by D1 receptors essential for controlling movements in Parkinson's disease

NIH-funded researchers test new gene therapy to improve visual function in mice

Neuron firing patterns in IT cortex linked with object-recognition tasks

Songbirds may help researchers find cure for Huntington’s disease

Experimental drug shows promise in mice with multiple sclerosis

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