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Research finding could open new opportunities for treating Huntington's disease

Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene to the inherited disease more than 20 years ago

24 Jun 2014

Gelesis100 capsule leads to greater weight loss in overweight, obese individuals

A new "smart pill" called Gelesis100 safely leads to greater weight loss in overweight and obese individuals compared with those who receive an active comparator/placebo capsule, while all subjects have similar diet and exercise instructions, an international multicenter study finds.

24 Jun 2014

Animal study: Common BPA substitute alters brain development, causes hyperactive behavior

A chemical found in many "BPA free" consumer products, known as bisphenol S (BPS), is just as potent as bisphenol A (BPA) in altering brain development and causing hyperactive behavior, an animal study finds.

24 Jun 2014

Death rates remain higher for African-Americans with colon cancer

African-Americans with colon cancer are half as likely as Caucasian patients to have a type of colon cancer that is linked to better outcomes. The finding may provide insight into why African-Americans are more likely to die of colon cancer than Caucasians with the same stage of disease.

24 Jun 2014

Nearly 4% of U.S. babies are born before full-term without medical indication, study finds

A large new study, covering millions of U.S. births over 15 years, finds that substantial numbers of babies, nearly one in 25, are born earlier than medically justified, through elective cesarean sections and elective induced labor. The study reinforces long-standing recommendations by professional medical and public health organizations against early-term deliveries without appropriate medical reasons.

24 Jun 2014

UK scientists unlock untapped genetic information to better understand Intellectual Disability in children

Teams of leading UK scientists have joined forces to unlock an untapped source of genetic information in a bid to better understand and treat children with Intellectual Disability. Experts from Cambridge, Cardiff, and UCL (University College London) will be given unprecedented access to genetic information on intellectual disability from NHS Regional Genetics Centres across the UK as part of a first phase study funded by the Medical Research Council and Medical Research Foundation.

24 Jun 2014

Mersana and Merck KGaA develop next-generation antibody-drug conjugates

Mersana Therapeutics, Inc., and the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, which operates as EMD Serono in the United States and Canada, announced today an agreement to collaboratively develop next-generation antibody-drug conjugates (ADCs).

24 Jun 2014

Clusters of protein linked to cancer warp cell membranes

Supercomputer simulations have shown that clusters of a protein linked to cancer warp cell membranes, according to scientists at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

24 Jun 2014

Researchers find possible biological reason why people with diabetes are prone to depression

Researchers have found a possible biological reason why people with diabetes are prone to depression.

23 Jun 2014

Women who develop gestational diabetes perform worse on cognitive function tests

Women who develop diabetes during pregnancy, called gestational diabetes, perform worse on cognitive function tests than do women with a normal pregnancy, according to a new study from Turkey.

23 Jun 2014

BioLineRx announces in-licensing of BL-1110 compound for treatment of neuropathic pain

BioLineRx Ltd., a clinical-stage biopharmaceutical company dedicated to identifying, in-licensing and developing promising therapeutic candidates, announced today it has in-licensed BL-1110, a novel compound for the treatment of neuropathic pain.

23 Jun 2014

New concept of organs on a chip may help study cancer metastasis

The recent development of the concept of organs on a chip opens the possibility of realistically studying human organs without the use of patients or animal testing.

23 Jun 2014

Overlooked DNA shuffling drives deadly paediatric brain tumour

One of the deadliest forms of paediatric brain tumour, Group 3 medulloblastoma, is linked to a variety of large-scale DNA rearrangements which all have the same overall effect on specific genes located on different chromosomes.

23 Jun 2014

Salmonella cases are not associated with Danish broiler meat, shows report

The number of Danes who contracted a salmonella infection reached a historic low level in 2013. More than half of those infected became ill during a trip abroad.

20 Jun 2014

Researchers discover crucial process that regulates development of blood vessels

Biologists at The Scripps Research Institute (TSRI) have discovered a crucial process that regulates the development of blood vessels.

19 Jun 2014

Apitope starts preclinical development of ATX-GD-459 for Graves' disease treatment

Apitope, the drug discovery and development company focused on disease-modifying treatments for patients with autoimmune and allergic diseases, announced today that it has started preclinical development of its novel peptide therapy ATX-GD-459 for the treatment of Graves' disease.

19 Jun 2014

UT Arlington researchers use portable device to map brain activity responses during cognitive activities

UT Arlington researchers have successfully used a portable brain-mapping device to show limited prefrontal cortex activity among student veterans with Post Traumatic Stress Disorder when they were asked to recall information from simple memorization tasks.

19 Jun 2014

Drug therapy for ADHD does not entail increased risk of suicide attempts

A new register-based study from Karolinska Institutet in Sweden shows that drug therapy for ADHD does not entail an increased risk of suicide attempts or suicide, as was previously feared. The results are published in the British Medical Journal (BMJ).

19 Jun 2014

Tumor necrosis factor alpha antagonists not linked with increased risk of cancer

In a study that included more than 56,000 patients with inflammatory bowel disease, use of a popular class of medications known as tumor necrosis factor alpha antagonists was not associated with an increased risk of cancer over a median follow-up of 3.7 years, although an increased risk of malignancy in the long term, or with increasing number of doses, cannot be excluded, according to a study in the June 18 issue of JAMA.

18 Jun 2014

Common mutation in gene with overweight results in elevated ALAT values in children

A study carried out at the Institute of Biomedicine of the University of Eastern Finland shows that a common mutation in the PNPLA3 gene combined with overweight results in elevated ALAT values in children.

18 Jun 2014

X linked News and Research

Research finding could open new opportunities for treating Huntington's disease

Gelesis100 capsule leads to greater weight loss in overweight, obese individuals

Animal study: Common BPA substitute alters brain development, causes hyperactive behavior

Death rates remain higher for African-Americans with colon cancer

Nearly 4% of U.S. babies are born before full-term without medical indication, study finds

UK scientists unlock untapped genetic information to better understand Intellectual Disability in children

Mersana and Merck KGaA develop next-generation antibody-drug conjugates

Clusters of protein linked to cancer warp cell membranes

Researchers find possible biological reason why people with diabetes are prone to depression

Women who develop gestational diabetes perform worse on cognitive function tests

BioLineRx announces in-licensing of BL-1110 compound for treatment of neuropathic pain

New concept of organs on a chip may help study cancer metastasis

Overlooked DNA shuffling drives deadly paediatric brain tumour

Salmonella cases are not associated with Danish broiler meat, shows report

Researchers discover crucial process that regulates development of blood vessels

Apitope starts preclinical development of ATX-GD-459 for Graves' disease treatment

UT Arlington researchers use portable device to map brain activity responses during cognitive activities

Drug therapy for ADHD does not entail increased risk of suicide attempts

Tumor necrosis factor alpha antagonists not linked with increased risk of cancer

Common mutation in gene with overweight results in elevated ALAT values in children

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