B Cell News and Research

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Moberg Derma receives Vinnova grant to develop Limtop for actinic keratosis, genital warts

Moberg Derma AB has been granted 4 MSEK by Vinnova for the development of Limtop, an innovative formulation for the treatment of actinic keratosis, genital warts and basal cell cancer.

15 Nov 2011

Tigecycline antibiotic shows promise against leukemia

Clinician-scientists in the Princess Margaret Cancer Program have found a promising approach to treating leukemia, using an old drug in a new way.

15 Nov 2011

Stem cell therapy within 2 or 3 weeks does not improve heart function after attack

A research network led by a Mayo Clinic physician found that stem cells obtained from bone marrow delivered two to three weeks after a person has a heart attack did not improve heart function.

15 Nov 2011

Stem cell injections within two weeks may not help in post heart attack recovery

University Hospitals Case Medical Center researchers could still be close to giving heart attack patients a second chance-just not as they originally thought.

15 Nov 2011

Encouraging results from KAEL-GemVax GV1001 Phase II trial on NSCLC

KAEL-GemVax, a leading oncology biopharmaceutical company, today announced that results from a Phase II trial (CTN-2006) in Stage III non-small cell lung cancer (NSCLC) patients vaccinated with the telomerase peptide GV1001 after chemoradiotherapy and an 8-year update from a phase I/II trial have been published in the November issue of Clinical Cancer, the journal of the American Association for Cancer Research.

15 Nov 2011

Fact-checking Romney's debate performance

CNN examines comments made by GOP presidential hopeful Mitt Romney regarding the possible dollar savings that could result by repealing the health law, while the AP revisits his positions regarding the Massachusetts health law he signed while that state's governor. Also in the news, more on Rick Perry's Texas and where the candidates state on health research.

15 Nov 2011

Mtb produces specific protein that allows it to defuse and bypass body's security system

Tuberculosis, which kills over 2 million people each year, is caused primarily by infectious bacteria known as Mycobacterium tuberculosis - or Mtb. Mtb targets human immune cells as part of its strategy to avoid detection, effectively neutralizing the body's immune response.

15 Nov 2011

Prox1 gene plays a critical role in formation and maintenance of lymphatic system

A century after the valves that link the lymphatic and blood systems were first described, St. Jude Children's Research Hospital scientists have detailed how those valves form and identified a gene that is critical to the process.

15 Nov 2011

New animal research finds life experiences influence brain development, behavior

Scientists presented new research today demonstrating the impact life experiences can have on genes and behavior. The studies examine how such environmental information can be transmitted from one generation to the next - a phenomenon known as epigenetics.

15 Nov 2011

Lentigen, UH Case Medical Center initiate LG631 Phase I trial in glioblastoma

University Hospitals (UH) Case Medical Center, Case Western Reserve University School of Medicine and Lentigen Corporation announced today the initiation of a novel Phase I clinical trial of LG631 gene therapy for the protection of hematopoietic stem cells (HSCs) from the dose limiting toxicity of chemotherapy with Temodar.

15 Nov 2011

Radon exposure may increase risk of non-melanoma skin cancer

A new study published this week suggests that a link may exist between radon exposure and non-melanoma skin cancer.

15 Nov 2011

Women with inflammatory breast cancer now have a chance of treatment

Women with the deadliest and rarest form of breast cancer now have a chance of treatment where once their options were severely limited, thanks to a new discovery by George Mason University researchers.

15 Nov 2011

Mesoblast reports positive Revascor Phase 2 heart failure trial results

Regenerative medicine company Mesoblast Limited today announced positive Phase 2 heart failure trial results of its allogeneic, or off-the-shelf, adult stem cell product Revascor after all patients had completed a minimum follow-up of 12 months, and a mean follow-up of 22 months.

15 Nov 2011

New clues about connections among fat, inflammation and insulin resistance

In a new study, scientists report that they substantially curbed weight gain, improved metabolism, and improved the efficacy of insulin in mice by engineering them to express a specific human enzyme in their fat tissue. Although the obesity prevention came at the significant cost of widespread inflammation, the research offers new clues about the connections among obesity, insulin resistance and type 2 diabetes, and inflammation.

14 Nov 2011

Fetal stem cells play an important role in inducing maternal cardiac repair

Researchers from Mount Sinai School of Medicine have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury.

14 Nov 2011

Lower glycemic index diet may delay onset of AMD-like lesions

Feeding older mice a lower glycemic index (GI) diet consisting of slowly-digested carbohydrates delays the onset of age-related, sight-threatening retinal lesions, according to a new study from the Laboratory for Nutrition and Vision Research at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University.

14 Nov 2011

Viewpoints: Conservative legal path on health law; Romney's plans for Medicare and vets; States moving on reform

A federal appeals court in the District of Columbia endorsed the constitutionality of health care reform this week in an opinion as notable for its authorship as for its legal reasoning. The majority opinion in the 2-to-1 decision was written by Judge Laurence Silberman, a stalwart of conservative jurisprudence whose views are said to be enormously influential in conservative legal circles.

14 Nov 2011

Cultured ES cells can self-organize into three-dimensional tissue-like structures

The possibility that functional, three-dimensional tissues and organs may be derived from pluripotent cells, such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), represents one of the grand challenges of stem cell research, but is also one of the fundamental goals of the emerging field of regenerative medicine.

14 Nov 2011

Stem cell bandage human clinical trial for torn meniscal cartilage

The company behind a pioneering stem cell bandage, believed to be the world's first adult and autologous (patient's own) stem cell treatment designed to heal torn meniscal cartilage, can now take the technology to human clinical trials thanks to an investment from one of the UK's most successful entrepreneurs.

14 Nov 2011

HemaCare reports third quarter revenue of $4.0M from continuing operations

HemaCare Corporation announced today that the Company generated 2011 third quarter revenue of $4.0 million from continuing operations and net income of $512,000 or $0.05/share, including net income from discontinued operations of $1,090,000.

14 Nov 2011

B Cell News and Research

Moberg Derma receives Vinnova grant to develop Limtop for actinic keratosis, genital warts

Tigecycline antibiotic shows promise against leukemia

Stem cell therapy within 2 or 3 weeks does not improve heart function after attack

Stem cell injections within two weeks may not help in post heart attack recovery

Encouraging results from KAEL-GemVax GV1001 Phase II trial on NSCLC

Fact-checking Romney's debate performance

Mtb produces specific protein that allows it to defuse and bypass body's security system

Prox1 gene plays a critical role in formation and maintenance of lymphatic system

New animal research finds life experiences influence brain development, behavior

Lentigen, UH Case Medical Center initiate LG631 Phase I trial in glioblastoma

Radon exposure may increase risk of non-melanoma skin cancer

Women with inflammatory breast cancer now have a chance of treatment

Mesoblast reports positive Revascor Phase 2 heart failure trial results

New clues about connections among fat, inflammation and insulin resistance

Fetal stem cells play an important role in inducing maternal cardiac repair

Lower glycemic index diet may delay onset of AMD-like lesions

Viewpoints: Conservative legal path on health law; Romney's plans for Medicare and vets; States moving on reform

Cultured ES cells can self-organize into three-dimensional tissue-like structures

Stem cell bandage human clinical trial for torn meniscal cartilage

HemaCare reports third quarter revenue of $4.0M from continuing operations

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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