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WHO: Progress towards global vaccination targets 'far off track'

Progress towards global vaccination targets for 2015 is far off track with 1 in 5 children still missing out on routine life-saving immunizations that could avert 1.5 million deaths each year from preventable diseases. In the lead-up to World Immunization Week 2015 (24 -30 April), the World Health Organization is calling for renewed efforts to get progress back on course.

24 Apr 2015

Alnylam announces clinical data from patisiran Phase 2 OLE study for treatment of patients with FAP

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today initial 12-month clinical data from its ongoing Phase 2 open-label extension (OLE) study with patisiran, an investigational RNAi therapeutic in development for the treatment of transthyretin (TTR)-mediated amyloidosis (ATTR amyloidosis) in patients with familial amyloidotic polyneuropathy (FAP).

24 Apr 2015

Case Western Reserve and MIT receive $1.7 million to explore potential treatments for Down syndrome

Thanks to the generosity of a philanthropy dedicated to children's issues, renowned Down syndrome researcher Alberto Costa, MD, PhD, has taken yet another step toward making Northeast Ohio the nation's leader in exploring potential treatments of the genetic condition that affects 400,000 people in the U.S.

23 Apr 2015

Study: Childhood cancer survivors need better care throughout their lives

Children with cancer have a good chance of surviving the disease--today more than 80 percent survive because of advances in treatment and care. However, recent studies have shown that some of these more than 420,000 U.S. childhood cancer survivors face future health-related challenges as they become adults such as a second cancer diagnosis, cardiac failure, or other severe medical complications.

22 Apr 2015

World Veterans Federation supports approved technology for tinnitus relief among veterans

TINNITUS, a debilitating "ringing in the ears", has become the No. 1 service- connected disability among veterans, surpassing post-traumatic stress disorder.

22 Apr 2015

New research examines what happens when MS patients discontinue their medication

New research led by NYU Langone Medical Center examines what happens when a patient with multiple sclerosis (MS) who is clinically stable stops taking their medication.

22 Apr 2015

Tal Medical raises $14 million funding round from new and existing investors

Tal Medical, a clinical-stage medical device company developing a new treatment for depression and other psychiatric disorders, today announced a $14 million funding round from existing investor PureTech, a new institutional investor, and several prominent individual investors.

21 Apr 2015

UCLA-led stroke study selected as one of 10 most outstanding research papers by CRF

A UCLA-led study on improving stroke care was selected by the Clinical Research Forum (CRF) as one of the 10 most outstanding research papers written by teams from across the nation in 2014. The organization highlighted the papers at its fourth annual awards ceremony in Washington, D.C. on April 16.

21 Apr 2015

Study: Extending natalizumab treatment effective in preventing MS symptoms

In a study of 1,964 patients with multiple sclerosis (MS) led by researchers at the NYU Langone Multiple Sclerosis Comprehensive Care Center, extending the dose of natalizumab from 4 weeks up to 8 weeks was shown to be well-tolerated and effective in patients, and resulted in no cases of the potentially fatal side effect progressive multifocal leukoencephalopathy (PML).

21 Apr 2015

Two existing drugs may potentially become new drug target for multiple sclerosis

Two drugs already on the market -- an antifungal and a steroid -- may potentially take on new roles as treatments for multiple sclerosis. According to a study published in Nature today, researchers discovered that these drugs may activate stem cells in the brain to stimulate myelin producing cells and repair white matter, which is damaged in multiple sclerosis.

20 Apr 2015

Study confirms benefits of removing blood clots after stroke

A technique that removes blood clots from large brain blood vessels reduced disability after stroke in a trial conducted in Catalonia, Spain, and co-led by an expert from the University of Pittsburgh School of Medicine.

20 Apr 2015

Endovascular therapy best treatment option for stroke patients

A research paper published in the New England Journal of Medicine (NEJM) today confirms earlier findings that a procedure called endovascular therapy (ET) for ischemic stroke is the best treatment option for many patients by reducing the incidents of disability.

17 Apr 2015

Clot removal improves outcomes in stroke patients

Stroke is the leading cause of severe long-term disability in the United States, and less than 40 percent of patients who experience the most severe form of stroke regain functional independence if they receive the standard drug intervention alone.

17 Apr 2015

Inflammation plays causal role in neurologic changes associated with Lyme disease

About 15% of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. New research indicates that inflammation plays a causal role in the array of neurologic changes associated with Lyme disease, according to a study published in The American Journal of Pathology.

17 Apr 2015

New longer-term data on Genzyme's relapsing MS treatments to be presented at AAN 2015

Genzyme, a Sanofi company, announced today that new longer-term data on its relapsing multiple sclerosis treatments, Aubagio (teriflunomide) and Lemtrada (alemtuzumab), will be featured during the 67th annual meeting of the American Academy of Neurology being held in Washington, D.C. April 18-25.

15 Apr 2015

MEMREHAB trial shows that treatment with mSMT may be adversely affected by cognitive dysfunction

Kessler Foundation researchers published a subanalysis of their MEMREHAB trial, which shows that treatment with the modified Story Memory Technique (mSMT) may be affected by cognitive dysfunction. Investigators looked at the influence of processing speed on benefits of the mSMT, a 10-session cognitive intervention protocol shown to improve new learning and memory in individuals with MS.

13 Apr 2015

Broader use of psychological testing may improve process for social security disability determination

Broader use of standardized psychological testing for applicants submitting disability claims to the U.S. Social Security Administration should improve the accuracy and consistency of disability determinations, says a new report from the Institute of Medicine.

13 Apr 2015

People with learning disabilities may become victim or perpetrator of crime while online

People with learning (intellectual) disabilities have historically been marginalised from mainstream society, and have had limited choice and control over their lives. While movements to achieve greater equality have had success, the rapid advancement of modern technology risks creating a new form of digital exclusion.

13 Apr 2015

Caesarean sections can save lives, but often performed without medical need

Caesarean section is one of the most common surgeries in the world, with rates continuing to rise, particularly in high- and middle-income countries.

10 Apr 2015

UofL-led study focuses on flu vaccine for children with neurological disorders

Children who have neurological disorders such as cerebral palsy or epilepsy are no more likely to be vaccinated against influenza than youngsters without these conditions, despite the increased risk for complications from flu these children experience.

10 Apr 2015

Disability News and Research

WHO: Progress towards global vaccination targets 'far off track'

Alnylam announces clinical data from patisiran Phase 2 OLE study for treatment of patients with FAP

Case Western Reserve and MIT receive $1.7 million to explore potential treatments for Down syndrome

Study: Childhood cancer survivors need better care throughout their lives

World Veterans Federation supports approved technology for tinnitus relief among veterans

New research examines what happens when MS patients discontinue their medication

Tal Medical raises $14 million funding round from new and existing investors

UCLA-led stroke study selected as one of 10 most outstanding research papers by CRF

Study: Extending natalizumab treatment effective in preventing MS symptoms

Two existing drugs may potentially become new drug target for multiple sclerosis

Study confirms benefits of removing blood clots after stroke

Endovascular therapy best treatment option for stroke patients

Clot removal improves outcomes in stroke patients

Inflammation plays causal role in neurologic changes associated with Lyme disease

New longer-term data on Genzyme's relapsing MS treatments to be presented at AAN 2015

MEMREHAB trial shows that treatment with mSMT may be adversely affected by cognitive dysfunction

Broader use of psychological testing may improve process for social security disability determination

People with learning disabilities may become victim or perpetrator of crime while online

Caesarean sections can save lives, but often performed without medical need

UofL-led study focuses on flu vaccine for children with neurological disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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