Genes News and Research

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Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

New antimicrobial coating material effectively kills bacteria and viruses

Researchers have used a common disinfectant and antiseptic to create a new antimicrobial coating material that effectively kills bacteria and viruses, including MRSA and Covid-19.

11 May 2023

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

An important genetic mechanism of drug resistance in one of the deadliest human malaria parasites has been identified in a new study published in Nature Microbiology.

11 May 2023

Research sheds light on the early cellular events that give rise to pancreatic cancer

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

11 May 2023

New NIH program seeks to discover and catalog the breadth of somatic mosaicism in human tissues

The National Institutes of Health is launching a new program, the Common Fund's Somatic Mosaicism Across Human Tissues Network, that aims to transform our knowledge of how much genetic variation there is in the cells and tissues throughout our bodies.

11 May 2023

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Announcing a new article publication for Zoonoses journal. Aspergillus fumigatus infection in the lungs is accompanied by the recruitment of innate immune cells, phagocytosis, and the release of inflammatory factors.

11 May 2023

Study extends understanding of m6A modification as biological pathway underlying atrial fibrillation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Numerous single nucleotide polymorphisms (SNPs) have been identified as genetic contributors to atrial fibrillation (AF).

11 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

Neanderthal genes shape human noses

Research reports a study on the genetics of facial features in Latin Americans using automatic landmarking of 2D portraits and genome-wide association analysis. The study identified novel regions associated with facial features, including a region in 1q32.3 that shows introgression from Neanderthals and influences nasal height.

10 May 2023

Study sheds light on a possible pharmacological approach to treat cardiac arrhythmias

Scientists at Simon Fraser University (SFU) and the Lankenau Institute for Medical Research (LIMR) near Philadelphia have found that a drug discovered at SFU and patented several years ago may have potential lifesaving results in the treatment of conditions leading to sudden cardiac death.

10 May 2023

Rising tide of chronic disease can be traced to impaired salugenesis, incomplete healing

In medicine and science, the term "pathogenesis" describes the origin and development of disease. There is not, however, a broadly accepted term to describe the other half of the equation: the process of healing and recovery.

10 May 2023

New approaches to promote healthspan from an epigenetic perspective

A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "How can we modulate aging through nutrition and physical exercise? An epigenetic approach."

10 May 2023

COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth

The intravenous delivery of immune-modulating cells may someday slow the expansion of bulges in the aorta, known as abdominal aortic aneurysms.

10 May 2023

Leveraging proteomics datasets to discover potential therapeutic targets for cancer patients

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Using cancer proteomics data to identify gene candidates for therapeutic targeting."

10 May 2023

Researchers create new "pangenome" that provides better view of human genome

When it was launched in April 2003, the Human Genome Project helped revolutionize biomedical research by providing scientists a reference map that allowed them to analyze DNA sequences for genetic clues to the origins of a host of diseases.

10 May 2023

Researchers release new high-quality collection of reference human genome sequences

Researchers have released a new high-quality collection of reference human genome sequences that captures substantially more diversity from different human populations than what was previously available.

10 May 2023

Environmental PAH exposure associated with increased rheumatoid arthritis risk

The amount of environmental exposure to polycyclic aromatic hydrocarbons, or PAH for short, is strongly linked to a person's risk of developing rheumatoid arthritis, suggests research published in the open access journal BMJ Open.

10 May 2023

MGI empowers the completion of nearly 60,000 samples for the million microbiome of humans project

Through the Million Microbiome of Humans Project, MGI Tech is building a comprehensive microbiome database to support global health and research initiatives.

From MGI 10 May 2023

New SNAP approach to customizing T cell-based immunotherapies

University of Pittsburgh researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other immunotherapies for treating cancer and other diseases.

9 May 2023

Genes News and Research

Targeting the hemoglobin problem in sickle cell disease using a new drug

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

New antimicrobial coating material effectively kills bacteria and viruses

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

Research sheds light on the early cellular events that give rise to pancreatic cancer

New NIH program seeks to discover and catalog the breadth of somatic mosaicism in human tissues

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Study extends understanding of m6A modification as biological pathway underlying atrial fibrillation

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

Neanderthal genes shape human noses

Study sheds light on a possible pharmacological approach to treat cardiac arrhythmias

Rising tide of chronic disease can be traced to impaired salugenesis, incomplete healing

New approaches to promote healthspan from an epigenetic perspective

COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth

Leveraging proteomics datasets to discover potential therapeutic targets for cancer patients

Researchers create new "pangenome" that provides better view of human genome

Researchers release new high-quality collection of reference human genome sequences

Environmental PAH exposure associated with increased rheumatoid arthritis risk

MGI empowers the completion of nearly 60,000 samples for the million microbiome of humans project

New SNAP approach to customizing T cell-based immunotherapies

eBook: Using iPSCs models for human disease research and drug discovery eBook

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