Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Oct4 gene may play significant role in preventing underlying cause of heart attacks, strokes

A gene that scientific dogma insists is inactive in adults actually plays a vital role in preventing the underlying cause of most heart attacks and strokes, researchers at the University of Virginia School of Medicine have determined.

18 May 2016

Novel therapeutic approach to treat leukaemia patients

Cancer cells have an abnormal cell division and survival machinery - they grow faster than they die. For their permanent development, they produce an excess of growth factors and nutrients and block the body's own safety mechanisms.

17 May 2016

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

AbbVie, a global biopharmaceutical company, today announced The Lancet Oncology published results from the Phase 2, single arm, open label trial studying venetoclax in patients with relapsed/refractory (R/R) chronic lymphocytic leukaemia (CLL) with 17p deletion.

17 May 2016

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

Ipsen S.A., a global specialty-driven pharmaceutical company, and the Institute of Molecular and Cell Biology (IMCB), a research institute under the aegis of the Agency for Science, Technology and Research (A*STAR), Singapore, today announced the signature of a research partnership to study the intracellular trafficking of botulinum neurotoxins (BoNTs) within neurons.

16 May 2016

ISSCR releases updated guidelines for stem cell research, development of new therapies

The International Society for Stem Cell Research, the world's largest professional organization of stem cell scientists, today released newly updated guidelines for stem cell research and the development of new clinical therapies.

13 May 2016

Histone mutation linked to fatal pediatric brain tumor

A single defect in a gene that codes for a histone — a "spool" that wraps idle DNA — is linked to pediatric cancers in a study published today in the journal Science.

13 May 2016

Stimulating stem cells to make special type of cartilage may potentially heal broken bones

Stem cells could one day be stimulated to make a special type of cartilage to help repair large, hard-to-heal bone fractures - a potential boon for doctors treating big-money athletes, USC researchers say.

12 May 2016

Brazilian strain of Zika virus can cause severe birth defects

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first "direct experimental proof" that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

12 May 2016

Fast, new way to rule out potentially dangerous drugs using optogenetics

A team of researchers at the George Washington University has developed a faster method to predict whether potential new drugs will cause heart arrhythmias using optogenetics, a technique that uses light to control cells.

11 May 2016

Study suggests ways of minimizing DNA folding errors

Induced pluripotent stem cells hold promise for regenerative medicine because they can, in theory, turn into any type of tissue and because they are made from a patient's own adult cells, guaranteeing compatibility. However, the technique that turns adult cells into these iPS cells is not foolproof; after reverting to their pluripotent state, these cells don't always correctly differentiate back into adult cells.

11 May 2016

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes.

11 May 2016

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Scientists in Manchester, who have developed a stem cell gene therapy to reverse a fatal childhood illness, have agreed to work with a new therapeutics company to test it in a human trial.

11 May 2016

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

CoSTREAM project aims to find common mechanisms, pathways in stroke and Alzheimer's disease

Stroke and Alzheimer's disease are major diseases imposing a huge burden on aging societies. It has long been recognized that stroke and Alzheimer's disease often co-occur, and it has been speculated that the two disorders have an overlapping pathogenesis.

10 May 2016

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

The U.S. Centers for Disease Control and Prevention recently concluded that Zika virus infection in pregnant women can stunt neonatal brain development, leading to babies born with abnormally small heads, a condition known as microcephaly. Now, for the first time, researchers at University of California San Diego School of Medicine have determined one way Zika infection can damage developing brain cells.

9 May 2016

Study reveals glioblastoma subtypes tend to develop in different regions of the brain

Researchers at University of California San Diego School of Medicine have demonstrated that distinct types of glioblastoma, the most common form of brain cancer in adults, tend to develop in different regions of the brain. This finding provides an explanation for how the same cancer-causing mutation can give rise to different types of brain malignancies.

5 May 2016

New research shows molecular, cellular processes in human embroyo development

Despite significant biomedical advances in recent decades, the very earliest events of human development¬--those that occur during a critical window just after fertilization--have remained an unobservable mystery, until now.

5 May 2016

Certain sugars in the body play key role in colitis, colon cancer development

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn's disease and colon cancer.

5 May 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

To make a good framework for filling in missing bone, mix at least 30 percent pulverized natural bone with some special man-made plastic and create the needed shape with a 3-D printer. That's the recipe for success reported by researchers at The Johns Hopkins University in a paper published April 18 online in ACS Biomaterials Science & Engineering.

5 May 2016

LALES study analyzes risk, prevalence of early and late stage AMD among Latinos

The University of Southern California Roski Eye Institute researchers and clinicians published results of the largest population-based study of adult Latinos and age-related macular degeneration (AMD) in the National Eye Institute-funded "Los Angeles Latino Eye Study." The study, published in JAMA Ophthalmology, is the first to analyze the risk and prevalence of early and late stage AMD and its impact on quality of life for older Latinos.

4 May 2016

Stem Cells News and Research

Further Reading

Oct4 gene may play significant role in preventing underlying cause of heart attacks, strokes

Novel therapeutic approach to treat leukaemia patients

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

ISSCR releases updated guidelines for stem cell research, development of new therapies

Histone mutation linked to fatal pediatric brain tumor

Stimulating stem cells to make special type of cartilage may potentially heal broken bones

Brazilian strain of Zika virus can cause severe birth defects

Fast, new way to rule out potentially dangerous drugs using optogenetics

Study suggests ways of minimizing DNA folding errors

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

lncRNA in placenta may help protect unborn baby from invading pathogens

CoSTREAM project aims to find common mechanisms, pathways in stroke and Alzheimer's disease

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

Study reveals glioblastoma subtypes tend to develop in different regions of the brain

New research shows molecular, cellular processes in human embroyo development

Certain sugars in the body play key role in colitis, colon cancer development

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

LALES study analyzes risk, prevalence of early and late stage AMD among Latinos

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