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Cholera can be controlled with oral vaccines

Endemic cholera, a potentially fatal diarrheal disease found in the world's most impoverished countries, could be effectively controlled by orally vaccinating half of the affected populations once every two years for only pennies per dose, according to new findings by an international team of researchers led by Ira M. Longini Jr., Ph.D., a biostatistician in the Vaccine and Infectious Disease Institute at Fred Hutchinson Cancer Research Center in Seattle. Longini and colleagues will report their findings online Nov. 27 in PLoS Medicine.

27 Nov 2007

Australian researcher heralds a golden age in biomedical science

A senior University of Sydney researcher has heralded a 'golden age' of modern biochemistry and molecular biology brought about by our complete sequencing of the human genome.

27 Nov 2007

Experimental gene therapy trial for arthritis allowed to resume

Trials in the U.S. of a controversial and experimental gene therapy have been given the green light to resume following the tragic death of a volunteer in July.

27 Nov 2007

Wyeth receives European approval for TORISEL

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the European Commission has approved TORISEL (temsirolimus) for the first-line treatment of patients with advanced renal cell carcinoma (RCC) who have at least three of six prognostic risk factors. TORISEL is the only approved cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase, an important regulator of cell proliferation, cell growth and cell survival.

27 Nov 2007

Researchers transfer immune response to myeloma patient

Researchers at the University of Arkansas for Medical Sciences (UAMS) have for the first time transferred an immune response in a healthy individual to a patient with multiple myeloma, a cancer of the bone marrow, showing promise for cancer vaccination.

27 Nov 2007

Communication key to tackling cardiovascular disease

Despite the increasing evidence that managing high cholesterol reduces cardiovascular events, many people do not achieve recommended lipid levels.

27 Nov 2007

Children with bipolar disorder respond differently to facial expressions

Children with bipolar disorder respond differently to facial expressions than children without psychiatric disorders, according to a new study led by a Bradley Hospital researcher.

27 Nov 2007

New program finds safer ways for college students to cope with alcohol

Researchers from the University of Cincinnati are reporting on a pilot program aimed at curbing alcohol abuse among college students.

27 Nov 2007

Many prostate cancer patients receive wrong treatment

Prostate cancer patients often receive treatment that is contraindicated by pre-existing conditions, like urinary or bowel dysfunction, according to a new study.

26 Nov 2007

Hillary Clinton promises more funds for autism

Presidential aspirant Democrat Hillary Clinton has promised increased funding for research into autism.

26 Nov 2007

Researchers find new way to transplant new blood-forming stem cells into bone marrow of mice

Researchers at the Stanford University School of Medicine have taken a small but significant step, in mouse studies, toward the goal of transplanting adult stem cells to create a new immune system for people with autoimmune or genetic blood diseases.

22 Nov 2007

Mutant mice could provide genetic clues on human sight loss

Mutant mice could provide genetic clues to understanding incurable human sight loss resulting from retinal degeneration.

22 Nov 2007

Lung transplants for cystic fibrosis may not be such a good option

Researchers in the United States say lung transplants do little to improve the outcomes for children with severe cystic fibrosis (CF) and often increases their risk of dying.

22 Nov 2007

Potential link between congenital heart anomaly and migraines

Interventional cardiologists at Rush University Medical Centerare investigating whether a heart procedure may be the key to relieving migraines in patients with severe headaches.

21 Nov 2007

Peptide therapy used to prevent progression of Parkinson's

Researchers have successfully used a peptide to reverse biochemical, cellular and anatomical changes that occur in the brains of mice with Parkinson's disease (PD), and report success in preventing the disease from progression.

21 Nov 2007

First genome sequence of XDR strain of the bacterium Mycobacterium tuberculosis

An international collaboration led by researchers in the US and South Africa today announced the first genome sequence of an extensively drug resistant (XDR) strain of the bacterium Mycobacterium tuberculosis, one linked to more than 50 deaths in a recent tuberculosis (TB) outbreak in KwaZulu-Natal, South Africa.

21 Nov 2007

Oral drug sets a new survival standard for bone marrow cancer

Findings from two large, international clinical trials show "unprecedented" survival for patients with multiple myeloma, a blood cancer that occurs in the blood-making cells of bone marrow.

21 Nov 2007

Lung transplants do more harm than good to children with cystic fibrosis

Lung transplantation, the therapy almost every cystic fibrosis patient (CF) considers at some point to prolong survival, rarely helps children with the disease live longer and, in fact, often increases their risk of dying, University of Utah researchers conclude in the most extensive study of the issue to date.

21 Nov 2007

How can we know early who will benefit from tumor target therapy?

The precise tailoring of tumor target treatment for patients with cancer is an unmet challenge.

21 Nov 2007

Lenalidomide - dexamethasone combination effective against multiple myeloma

Pairing a new thalidomide derivative with a steroid slows progress of multiple myeloma, an incurable bone marrow cancer, and prolongs the lives of patients who have relapsed from previous treatment, researchers report in the Nov. 22 New England Journal of Medicine.

21 Nov 2007