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Novel cellular pathway may clarify how arterial inflammation develops into atherosclerosis

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis - deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide.

22 Jun 2018

Research does not confirm antidiabetic action of natural fatty acid derivatives

A research consortium between the healthcare company Sanofi and Johannes Gutenberg University Mainz investigated the antidiabetic action of certain natural fatty acids, so-called FAHFAs, which US-American scientists had reported in 2014.

21 Jun 2018

Study: Oxidative stress can be used against tumors to treat cancer

Oxidative stress can help tumors thrive, but one way novel cancer treatments work is by pushing levels to the point where it instead helps them die, scientists report.

21 Jun 2018

Oxygen consumption in human BAT increases after a meal, shows research

The importance of the human brown adipose tissue has become clearer during the past ten years. Using functional imaging, positron emission tomography, PET, it was possible to show that adult humans have functional BAT.

20 Jun 2018

Scientists point to potentially promising treatment target for deadly brain cancers

Scientists report finding a potentially promising treatment target for aggressive and deadly high-grade brain cancers like glioblastoma. But they also say the current lack of a drug that hits the molecular target keeps it from being advanced for testing as a therapeutic strategy for patients with few treatment options.

18 Jun 2018

Study shows how moderate consumption of alcohol can protect the heart

For at least 20 years, research has shown that for many people, moderate consumption of alcohol can protect the heart, but the reason for this is poorly understood.

18 Jun 2018

Fat and carb rich foods preferred by the brain

We might all be aware of the harmful effects of junk food on health. This does not stop our brains from craving fat-rich and sugar loaded foods finds a new study. The study titled, “Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward,” was published today in the latest issue of the journal Cell Metabolism.

14 Jun 2018

Scientists discover how cancer-targeting 'Natural Killer' cells are fueled in the body

Scientists have just made an important discovery as to how cancer-targeting 'Natural Killer' cells are fueled in the body, which has significant implications for related therapies.

14 Jun 2018

Non-invasive optical imaging detects early molecular signatures of disease

Chronic conditions including obesity, cardiovascular disease, and cancer often begin with early, subtle changes in cellular metabolism.

13 Jun 2018

Researchers discover new medicine that may fight against monogenic obesity

Around two to six per cent of all people with obesity develop obesity already in early childhood; it's in their genetic cards.

4 Jun 2018

Cancer cells can use lipid molecules as fuel for growth, shows study

Cancer cells can when the blood supply is low use lipid molecules as fuel instead of blood glucose. This has been shown in animal tumor models by researchers at Karolinska Institutet in Sweden in a study published in Cell Metabolism.

1 Jun 2018

Hunger peptides sent through the brain's fluid cause appetite, shows study

A USC study shows the brain's plumbing system serves double duty, flushing waste and channeling a hunger molecule that tells you when you should eat.

1 Jun 2018

Study: Disease-causing stomach bacterium shuts down energy production in host cells

Researchers report in a new study that the bacterium Helicobacter pylori - a major contributor to gastritis, ulcers and stomach cancer - resists the body's immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection.

31 May 2018

Weight gain may be the result of inefficient fat metabolism

Researchers from the Karolinska Institutet have shown that protracted weight gain can, in some cases, be attributed to a reduced ability to metabolise fat.

31 May 2018

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

Anyone who's taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure to potentially harmful chemicals are triggered by TRPA1, a calcium channel protein sometimes referred to as the "wasabi receptor."

25 May 2018