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Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

ALS -- amyotrophic lateral sclerosis -- is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow.

20 Aug 2018

Study offers possibility of squelching a focal epilepsy seizure before symptoms appear

Patients with focal epilepsy that does not respond to medications badly need alternative treatments.

17 Aug 2018

Discovery may help broaden the scope of defenses against HPV

Yale Cancer Center scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus infects cells.

16 Aug 2018

New discoveries show how protein droplets do more than keep cells’ interiors tidy

Inside cells, where DNA is packed tightly in the nucleus and rigid proteins keep intricate transport systems on track, some molecules have a simpler way of establishing order. They can self-organize, find one another in crowded spaces, and quickly coalesce into droplets - like oil in water.

15 Aug 2018

Newly discovered cytoskeleton utilized by cancer cells for survival

Researchers at Lund University in Sweden have discovered a cytoskeleton which provides the structure for mitochondria, the cell's energy producers.

15 Aug 2018

Real-time dynamic monitoring of cell's nucleus for effective cancer screening

To test for malignancy or monitor the effectiveness of cancer treatment, a person's tissue must be extracted, sent to a lab, stained and analyzed by a pathologist--a process that can take days to complete and is subject to human error.

15 Aug 2018

PARP inhibitors show promise for treating and preventing brain disorders

A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including amyotrophic lateral sclerosis, also called Lou Gehrig's disease, and some forms of frontotemporal degeneration, by halting the misplacement of specific proteins that affect nerve cells, according to a study published in Molecular Cell by researchers in the the School of Arts and Sciences and the Perelman School of Medicine at the University of Pennsylvania.

10 Aug 2018

New discovery could pave way for improved leukemia treatment

Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation, but until now, how it helps improve outcomes has remained unknown.

9 Aug 2018

Study: HDAC1 enzyme modifies molecular motor that drives neuron death

A biochemistry instructor curious about an enzyme discovered in the damaged neurons of people with multiple sclerosis made a leap toward a potential cure for countless neurodegenerative ills.

7 Aug 2018

Cocaine relapse is reduced in preclinical model with BDNF administration

Cocaine relapse was significantly reduced in a preclinical model when brain-derived neurotropic factor was applied to the nucleus accumbens deep in the brain immediately before cocaine-seeking behavior, report investigators at the Medical University of South Carolina in an article published online in June 2018 by Addiction Biology.

3 Aug 2018

World's major heart surgery organizations call for effective strategies to treat rheumatic heart disease

Experts from the world's major heart surgery organizations-including The Society of Thoracic Surgeons, the American Association for Thoracic Surgery, the Asian Society for Cardiovascular and Thoracic Surgery, and the European Association for Cardio-Thoracic Surgery-are calling for urgent action to develop and implement effective strategies for treating rheumatic heart disease, which affects 33 million people and kills 320,000 annually.

3 Aug 2018

Study provides new insights into how asthma develops and progresses

Of the more than 24 million people in the U.S. who have asthma, 10 percent have severe asthma - a form of the disease that does not respond to treatment.

3 Aug 2018

Monash researchers identify new mechanism used by Henipaviruses in infection

Henipaviruses are among the deadliest viruses known to man and have no effective treatments. The viruses include Hendra, lethal to humans and horses, and the Nipah virus, a serious threat in East and Southeast Asia.

3 Aug 2018

Researchers sequence complete mitochondrial genome of malaria mosquitoes

A team led by scientists from the Johns Hopkins Bloomberg School of Public Health has sequenced and annotated the first complete mitochondrial genome of Anopheles funestus, one of the main vectors of malaria in sub-Saharan Africa.

31 Jul 2018

Bile acids from the gut may offer new treatment for cocaine abuse

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb Flynn of Vanderbilt University, Aurelio Galli of the University of Alabama at Birmingham, and colleagues.

27 Jul 2018

New combination approach may help crush resistance to treatment in lung cancer patients

New-generation lung cancer drugs have been effective in a large number of patients, but within about a year, the patients tend to develop resistance to the therapy.

26 Jul 2018

Study: Blood test can predict response of advanced prostate cancer patients to treatments

An international collaborative study between Lawson Health Research Institute, Memorial Sloan Kettering Cancer Center, the Royal Marsden and Epic Sciences is one of the first to demonstrate that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival.

25 Jul 2018

Cell Nucleus News and Research

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

Study offers possibility of squelching a focal epilepsy seizure before symptoms appear

Discovery may help broaden the scope of defenses against HPV

New discoveries show how protein droplets do more than keep cells’ interiors tidy

Newly discovered cytoskeleton utilized by cancer cells for survival

Real-time dynamic monitoring of cell's nucleus for effective cancer screening

PARP inhibitors show promise for treating and preventing brain disorders

New discovery could pave way for improved leukemia treatment

Study: HDAC1 enzyme modifies molecular motor that drives neuron death

Cocaine relapse is reduced in preclinical model with BDNF administration

World's major heart surgery organizations call for effective strategies to treat rheumatic heart disease

Study provides new insights into how asthma develops and progresses

Monash researchers identify new mechanism used by Henipaviruses in infection

Researchers sequence complete mitochondrial genome of malaria mosquitoes

Bile acids from the gut may offer new treatment for cocaine abuse

New combination approach may help crush resistance to treatment in lung cancer patients

Study: Blood test can predict response of advanced prostate cancer patients to treatments

Neurobiologists identify new link between smell and memory

Study reveals how giant neurons in the brain may play huge role in generalized arousal

Restoring mitochondrial function to reverse aging-related skin wrinkles, hair loss in mice

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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