Helix News and Research

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Novel sortase-based techniques allow modification of a large variety of different proteins

Whitehead Institute scientists have created a method that site-specifically modifies proteins to exert control over their properties when administered therapeutically. The technique should be useful to increase potency, slow metabolism, and improve thermal stability of therapeutically useful proteins, such as interferon alpha 2 (IFN-alpha 2), which is used to treat variety of diseases, including leukemia, melanoma, and chronic hepatitis C.

10 Mar 2011

Novel study deepens understanding of how chromosome replication works

A novel study from the Swedish medical university Karolinska Institutet has deepened the understanding of how chromosome replication, one of life's most fundamental processes, works.

3 Mar 2011

Simpler method of making water-soluble short protein chains with spiral structures

Researchers have developed a simple method of making short protein chains with spiral structures that can also dissolve in water, two desirable traits not often found together. Such structures could have applications as building blocks for self-assembling nanostructures and as agents for drug and gene delivery.

25 Feb 2011

Chimerix announces completion of $45 million Series F financing

Chimerix, Inc., a pharmaceutical company developing orally-available broad spectrum antiviral therapeutics, today announced the completion of a $45 million Series F financing. New Leaf Venture Partners led the round, with participation by new investors Pappas Ventures and Morningside Group, as well as existing investors Canaan Partners, Sanderling Ventures, Alta Partners, Asset Management Company and Frazier Healthcare Ventures.

14 Feb 2011

Rapid detection of transiently folded single-molecule structures from 'intrinsically disordered proteins'

A team of scientists from The Scripps Research Institute and the University of California, San Diego (UCSD) have developed a novel technique to observe previously unknown details of how folded structures are formed from an intrinsically disordered protein. The insights could help scientists to better understand the mechanism of plaque formation in neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.

9 Feb 2011

Novel technique could speed up the development of peptide-based drugs against cancer

Researchers at the University at Buffalo have devised two new ways of "stapling" peptide helices to prevent these medically important molecules from losing their shape and degrading in the presence of enzymes.

9 Feb 2011

Scientists develop novel technique to detect disordered protein folding

A team of scientists from The Scripps Research Institute and the University of California, San Diego have developed a novel technique to observe previously unknown details of how folded structures are formed from an intrinsically disordered protein.

9 Feb 2011

Helix Medical to invest over $4M for new manufacturing facility in Costa Rica

Helix Medical, LLC, a global manufacturer for the medical device and healthcare industries, will soon begin construction on a new medical manufacturing facility in Costa Rica. Helix Medical signed a leasing agreement in The Coyol Free Trade Zone and Business Park in Alajuela, Costa Rica, just outside of San Jose. The company will invest more than $4M in the new plant that will soon employ more than 100 people.

7 Feb 2011

Golden Helix releases new Sequence Analysis Module for SNP & Variation Suite

Golden Helix, Inc. today announced the release of a new Sequence Analysis Module for its SNP & Variation Suite software. The new module introduces innovative tertiary analysis methods for next-generation DNA sequencing studies.

27 Jan 2011

Golden Helix accelerates copy number variation detection methodology

Golden Helix, Inc., today announced the incorporation of technologies that will greatly accelerate genetic research. By enabling the company's SNP & Variation Suite software to run on off-the-shelf video graphics cards, or GPUs, operations that took hours or days can now be completed in a fraction of the time - and without the need for expensive compute clusters or resorting to cloud-based computing. This novel ability will dramatically accelerate many forms of computationally expensive genetic analyses, including that of next generation sequencing data.

27 Oct 2010

UCSF professor receives National Medal of Science

UCSF Nobel laureate Stanley B. Prusiner, MD, UCSF professor of neurology and director of the Institute for Neurodegenerative Diseases, today (Oct. 15, 2010) was named to receive the National Medal of Science, the nation's highest honor for science and technology.

18 Oct 2010

Sirius collaborates with Golden Helix to advance diagnostic pipeline

Sirius Genomics, a developer of companion diagnostics, and Golden Helix, a global leader in genetic analysis solutions, announced today a collaboration under which Golden Helix will apply its expertise and technologies in SNP and copy number variant analysis and predictive modeling to advance development of Sirius' diagnostic pipeline.

13 Oct 2010

Helix completes GLP toxicology study milestone in L-DOS47 development program

Helix BioPharma Corp. today announced that it has completed its definitive GLP, rodent and primate, repeat-dose toxicology studies with L-DOS47. These studies demonstrated a good safety profile in an expanded number of rodent and primate test animals, building upon Helix's positive findings from its preliminary non-GLP toxicology studies.

12 Oct 2010

Researchers discover new mechanism of DNA repair process

Tucked within its double-helix structure, DNA contains the chemical blueprint that guides all the processes that take place within the cell and are essential for life. Therefore, repairing damage and maintaining the integrity of its DNA is one of the cell's highest priorities.

4 Oct 2010

Golden Helix refactors HSPH's software for studying disease heritability in families

Today, Golden Helix, Inc., a global leader in genetic analysis solutions, announced a collaboration with Harvard School of Public Health (HSPH) under which Golden Helix is refactoring PBAT, HSPH's software for studying disease heritability in families.

23 Sep 2010

Cellectis bioresearch, Helix Biocon collaborate to promote cGPS service in India

Cellectis bioresearch, the specialist in genome customization and subsidiary of Cellectis and Helix BioService & Consultants Pvt Ltd (Helix Biocon), today announced that they will join forces for the promotion of Cellectis bioresearch's meganuclease-based products and services in India.

20 Sep 2010

Helix BioPharma receives authorization to list shares on NYSE Amex stock exchange

Helix BioPharma Corp. today announced that it has been authorized to list its shares of common stock on the NYSE Amex stock exchange. The Company expects that shares of its common stock will begin trading on the NYSE Amex on September 15, 2010, under the trading symbol "HBP."

15 Sep 2010

Researchers unveil protection mechanism of telomeres from DNA repair

In the latest issue of the journal Nature, Miguel Godinho Ferreira, Principal Investigator at the Instituto Gulbenkian de Ciência (IGC) in Portugal, lead a team of researchers to shed light on a paradox that has puzzled biologists since the discovery of telomeres, the protective tips of chromosomes: while broken chromosome ends generated by DNA damage (such as radiation or cigarette smoke) are quickly joined together, telomeres are never tied to each other, thus allowing for the correct segregation of the genetic material into all cells in our body.

9 Sep 2010

Researchers develop tiny color-changing sensor molecules

A new approach to building an "artificial nose" using fluorescent compounds and DNA could accelerate the use of sniffing sensors into the realm of mass production and widespread use, say Stanford chemists. If their method lives up to its promise, it could one day detect everything from incipiently souring milk to high explosives.

21 Aug 2010

Helix BioPharma closes private placement of 4,530,000 units

Helix BioPharma Corp. today announced that it has closed a private placement of 4,530,000 units at $2.43 per unit.

7 Aug 2010

Helix News and Research

Novel sortase-based techniques allow modification of a large variety of different proteins

Novel study deepens understanding of how chromosome replication works

Simpler method of making water-soluble short protein chains with spiral structures

Chimerix announces completion of $45 million Series F financing

Rapid detection of transiently folded single-molecule structures from 'intrinsically disordered proteins'

Novel technique could speed up the development of peptide-based drugs against cancer

Scientists develop novel technique to detect disordered protein folding

Helix Medical to invest over $4M for new manufacturing facility in Costa Rica

Golden Helix releases new Sequence Analysis Module for SNP & Variation Suite

Golden Helix accelerates copy number variation detection methodology

UCSF professor receives National Medal of Science

Sirius collaborates with Golden Helix to advance diagnostic pipeline

Helix completes GLP toxicology study milestone in L-DOS47 development program

Researchers discover new mechanism of DNA repair process

Golden Helix refactors HSPH's software for studying disease heritability in families

Cellectis bioresearch, Helix Biocon collaborate to promote cGPS service in India

Helix BioPharma receives authorization to list shares on NYSE Amex stock exchange

Researchers unveil protection mechanism of telomeres from DNA repair

Researchers develop tiny color-changing sensor molecules

Helix BioPharma closes private placement of 4,530,000 units

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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