Immunodeficiency News and Research

RSS

Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Novel genetic test enables earlier, more accurate diagnosis of primary immunodeficiency disorders

Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections. More than 450 PIDs have been described, but timely and accurate diagnoses remain a challenge.

23 May 2022

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

A new study investigated whether a specific population of local Bmem cells in the proximal LNs produce secondary GC responses that are different from those at distal sites and if the location in humoral immunity is relevant only to nonlymphoid tissues.

23 May 2022

Investigation of long-COVID in children with immunodeficiency

A new study focused on evaluating the prevalence of characteristic symptoms of Long COVID in immunodeficient and immunocompetent children.

23 May 2022

Real-world vaccine effectiveness of mRNA-1273 and BNT1262b2 in immunocompromised adults

Researchers assessed the efficacy of COVID-19 vaccines in immunocompromised adults.

23 May 2022

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

Researchers performed a molecular analysis of cross-reactive antibodies targeted against the receptor-binding domain of SARS-CoV-2 strains among the general population.

20 May 2022

New study reveals the genetic mechanism behind severe staphylococcal infections

A common culprit of skin and respiratory infections, Staphylococcus aureus is highly unpredictable. Between 20 and 30 percent of people carry quiet colonies on their skin and in their nostrils, which seldom cause problems beyond the occasional rash.

19 May 2022

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

Researchers assessed the vaccine-induced humoral responses against SARS-CoV-2 post four different vaccination regimens comprising homologous and heterologous vaccine doses.

18 May 2022

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

A new study published in the journal Viruses aimed to report the effects of plasma infusion and then breastmilk ingestion as a therapy for persistent SARS-CoV-2 infection in a patient with a common variable immunodeficiency (CVID) phenotype.

18 May 2022

Study investigates COVID-19 vaccination in pregnancy

A new study discusses the risk of COVID-19-related complications in pregnancy and the role of vaccination in reducing this risk.

17 May 2022

Researchers explore COVID-19 vaccination in immunocompromised individuals

A new study discusses the safety and efficacy of the COVID-19 vaccination and potential strategies to optimize protection in patients with impaired immunity.

17 May 2022

Broad-spectrum polymeric antivirals against SARS-CoV-2

In a recent study published in the journal Advanced Science, researchers evaluated the potential and applicability of macromolecular viral inhibitors against respiratory viral pathogens.

17 May 2022

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

A study conducted at the University of São Paulo's Medical School (FM-USP) in Brazil, with results reported in an article published in the journal Immunity & Ageing, shows that chronic obstructive pulmonary disease (COPD) leads to premature senescence (age-related impairment) of the immune system.

13 May 2022

Study investigates antibody-mediated response against different SARS-CoV-2 variants

In a recent study posted to the bioRxiv* preprint server, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on antibody-mediated immunity.

10 May 2022

Deoxyribonucleic acid nanostructure sensor found to rapidly detect and inhibit SARS-CoV-2

Researchers reported on a three-layer designer deoxyribonucleic acid (DNA) nanostructure (DDN) strategy-based sensor designed by them for rapid and accurate SARS-CoV-2 detection and inhibition.

9 May 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

In a recent study published in Biomedicines, researchers explored the utility of natural killer (NK) cells in coronavirus disease 2019 (COVID-19).

28 Apr 2022

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

Researchers assessed the epigenetic aging in COVID-19 patients and its impact on COVID-19 severity by a genome-wide deoxyribonucleic acid methylation profiling analysis.

27 Apr 2022

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

Characteristics of viral infection super-spreaders

Researchers evaluated whether certain super-spreaders transmit viral infection better and the impacts of individual variance in epidemiological characteristics.

26 Apr 2022

Increased power and amplitude of memory B cells after SARS-CoV-2 mRNA booster

In a recent study published in the journal Nature, the researchers investigated the impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) booster vaccine on memory B cells.

25 Apr 2022

Immunodeficiency News and Research

Further Reading

Novel genetic test enables earlier, more accurate diagnosis of primary immunodeficiency disorders

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

Investigation of long-COVID in children with immunodeficiency

Real-world vaccine effectiveness of mRNA-1273 and BNT1262b2 in immunocompromised adults

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

New study reveals the genetic mechanism behind severe staphylococcal infections

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

Study investigates COVID-19 vaccination in pregnancy

Researchers explore COVID-19 vaccination in immunocompromised individuals

Broad-spectrum polymeric antivirals against SARS-CoV-2

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

Study investigates antibody-mediated response against different SARS-CoV-2 variants

Deoxyribonucleic acid nanostructure sensor found to rapidly detect and inhibit SARS-CoV-2

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Characteristics of viral infection super-spreaders

Increased power and amplitude of memory B cells after SARS-CoV-2 mRNA booster

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News