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Multi-signal processing guide RNAs: A new frontier in gene regulation

Guides typically assist tourists with directions, but the experience could be greatly enhanced if they offered personalized services tailored to individual interests.

22 Jul 2024

UH research identifies key mechanisms of skeletal muscle regeneration

Newly published research from the University of Houston College of Pharmacy identifies key mechanisms of skeletal muscle regeneration and growth of muscles following resistance exercise.

22 Jul 2024

Study: Danger circuit relies on neuropeptides, not neurotransmitters

In the split second as you accidentally touch the hot handle of a cast iron skillet, pain and a sense of danger rush in.

22 Jul 2024

Combination of sEphB4-HSA and pembrolizumab shows promise in HPV-negative EphrinB2 positive HNSCC

A new research paper was published in Oncotarget's Volume 15 on July 10, 2024, entitled, "Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma."

22 Jul 2024

USC scientists transform B cells into cancer and HIV destroyers

USC scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine's most formidable foes.

22 Jul 2024

Research uncovers dengue’s surprising invasion strategies

Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease.

22 Jul 2024

Research shows the ability of proteins to predict onset of many diverse diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

22 Jul 2024

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression.

22 Jul 2024

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study by an international team of researchers, published in Nature Communications.

22 Jul 2024

Empowering human intelligence: Strategies for healthy aging and memory

People can reduce their risk of age-related dementia by exercising their brains properly instead of Googling, according to a leading Canadian academic.

22 Jul 2024

Women with endometriosis have a significantly increased ovarian cancer risk, study finds

Researchers from the United States of America investigated the potential association between different subtypes of endometriosis and the incidence of ovarian cancer.

22 Jul 2024

Long-term immune changes persist in unvaccinated COVID-19 patients

Study reveals that unvaccinated individuals experience significant long-term changes in immune parameters up to ten months post-COVID-19 infection, with a shift towards a Th2 cytokine profile.

21 Jul 2024

Saffron: A golden remedy for modern health challenges

Review highlights saffron's potential in preventing and treating various human diseases through its bioactive compounds. Clinical and preclinical studies confirm saffron's benefits in conditions like maculopathy, depression, neurodegenerative diseases, and cancer.

21 Jul 2024

High mutation count in new COVID-19 variants does not increase immune evasion, study finds

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two recent and prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to Omicron.

19 Jul 2024

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

19 Jul 2024

UVA advances precision medicine to defeat breast cancer with Komen grant

Through precision medicine, the University of Virginia is working toward a world in which no more pink ribbons are necessary. To that end, Susan G. Komen announced support this summer for the UVA School of Engineering and Applied Science's efforts to apply systems biology research to defeat breast cancer.

19 Jul 2024

Unexpected T-cell reactions to adenoviral COVID-19 vaccines discovered

Researchers from the University of Liverpool's Centre for Drug Safety Science have identified unpredicted T-cell immune responses to the adenoviral (Oxford/AstraZeneca and Janssen) COVID-19 vaccines, but not to the mRNA vaccines.

19 Jul 2024

Unraveling the rhythmic gene expression in legume-rhizobia symbiosis

Legumes thrive in low-nitrogen environments by partnering with rhizobia, soil bacteria that convert atmospheric nitrogen into ammonium, a usable form for the plants.

19 Jul 2024

Collaborative grant program boosts health research across Tennessee

Researchers from the University of Tennessee Health Science Center College of Medicine-Knoxville; the University of Tennessee, Knoxville; and the University of Tennessee Health Science Center Office of Research understand the challenges affecting the health and wellness of Tennesseans.

19 Jul 2024

Study reveals a promising approach to developing universal influenza vaccine

New research led by Oregon Health & Science University reveals a promising approach to developing a universal influenza vaccine - a so-called "one and done" vaccine that confers lifetime immunity against an evolving virus.

19 Jul 2024