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PD MED trial: Levodopa drug better for long-term treatment of newly diagnosed PD

For long-term treatment of newly diagnosed Parkinson’s disease (PD), the old drug levodopa provides better mobility and a higher quality of life than the two main alternatives, dopamine agonists (DA) and monoamine oxidase type B inhibitors (MAOBI), according to the largest-ever trial of PD treatment (PD MED), published in The Lancet.

13 Jun 2014

Fighting off illness causes sleep deprivation and affects memory

Sickness-induced insomnia is common because of link between brain and immune system. Fighting off illness- rather than the illness itself- causes sleep deprivation and affects memory, a new study has found.

13 Jun 2014

Use of opioid linked to higher levels of dissatisfaction following spine surgery

A new study appearing in the Journal of Bone and Joint Surgery (JBJS) links the use of opioid pain relievers (prescription medications, such as Percocet) to less improvement and higher levels of dissatisfaction following spine surgery.

13 Jun 2014

Human mind can rapidly absorb new information by synchronization of brain waves

The human mind can rapidly absorb and analyze new information as it flits from thought to thought. These quickly changing brain states may be encoded by synchronization of brain waves across different brain regions, according to a new study from MIT neuroscientists.

13 Jun 2014

Adolescents tend to be more powerful in influencing friends to start smoking than to quit

Adolescents tend to be more powerful in influencing their friends to start smoking than in helping them to quit, according to sociologists.

13 Jun 2014

One-third of PsA patients not receiving adalimumab doses to achieve optimal clinical benefit

Data presented today at the European League Against Rheumatism Annual Congress showed that a significant number of patients with psoriatic arthritis (PsA) were not receiving doses of the tumour necrosis factor-alpha (TNFα) inhibitor adalimumab necessary to achieve optimal clinical benefit.

12 Jun 2014

People with obesity gene FTO tend to gain more weight as they age

A new study from Uppsala University demonstrates that elderly humans carrying a common variant of the fat mass and obesity gene FTO also have a shifted endocrine balance. Low blood concentrations of the satiety hormone leptin and high blood concentrations of the hunger promoting hormone ghrelin makes carriers of the FTO gene put on weight.

12 Jun 2014

Cancer drug offers protection against thrombosis

Case Western Reserve University researchers have discovered that an existing drug used to help cancer patients has the potential to protect thousands of others from the often-deadly impact of vascular clots.

12 Jun 2014

Exercise transiently suppresses inflammation in rheumatic disease

Research findings presented today at the European League Against Rheumatism Annual Congress suggest that exercise transiently suppresses local and systemic inflammation, reinforcing the beneficial effects of exercise and the need for this to be regular in order to achieve clinical efficacy in rheumatic disease.

12 Jun 2014

Study examines effect of phthalate exposure in humans’ sperm epigenetics

A new three-year, $440,000 study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst is now underway to investigate whether phthalate levels in expectant fathers have an effect on the couples' reproductive success, via epigenetic modifications of sperm DNA.

12 Jun 2014

Researchers study structural aspects of DNA-particle/lipid interface directly using x-ray scattering

Scientists seeking ways to engineer the assembly of tiny particles measuring just billionths of a meter have achieved a new first-the formation of a single layer of nanoparticles on a liquid surface where the properties of the layer can be easily switched.

11 Jun 2014

Brain structure linked to psychosis symptoms

A study of patients across the psychosis spectrum supports an association between brain structure and psychosis symptoms.

11 Jun 2014

Long-term follow-up post bariatric surgery linked with more frequent diabetes remission

In a study that included long-term follow-up of obese patients with type 2 diabetes, bariatric surgery was associated with more frequent diabetes remission and fewer complications than patients who received usual care, according to a study in the June 11 issue of JAMA, a diabetes theme issue.

11 Jun 2014

Hydrolyzed formula does not lower diabetes linked autoantibodies in infants at risk for type 1 diabetes

Among infants at risk for type 1 diabetes, the use of a hydrolyzed formula (one that does not contain intact proteins) compared with a conventional formula did not reduce the incidence of diabetes-associated autoantibodies after 7 years of follow-up, according to a study in the June 11 issue of JAMA, a diabetes theme issue.

11 Jun 2014

Study presents oxytocin as latest treatment target for age-related muscle wasting

Researchers at the University of California, Berkeley, have discovered that oxytocin -- a hormone associated with maternal nurturing, social attachments, childbirth and sex -- is indispensable for healthy muscle maintenance and repair, and that in mice, it declines with age.

11 Jun 2014

Virginia budget plan moving forward without Medicaid expansion

After the abrupt resignation of a Democrat switched the state Senate to Republican control, Democrats began negotiating on a spending plan that no longer includes the governor's priority of expanding health care coverage to low-income residents.

11 Jun 2014

EU-funded project aims to identify potential new targets for cancer therapy

Targeted therapies have revolutionised the treatment of cancer since they were first introduced. Amongst the first medications approved in Europe, was the breast cancer drug Herceptin, which was approved in 2000. Then, the drug Glivec, was initially introduced to treat a certain form of leukaemia, and approved in 2001. Targeted therapies specifically inhibit molecules within so-called signalling pathways that usually control cell growth, death and differentiation. If they are altered, for example falsely inactivated or activated, the cells may start growing in an uncontrolled manner.

11 Jun 2014

Researchers discover strong genetic risk factor for type 2 diabetes in Latin American patients

In the largest study of its kind published to date, an international team of researchers in Mexico and the United States has discovered a strong genetic risk factor for type 2 diabetes that primarily affects Latin American patients, but is rare elsewhere.

11 Jun 2014

Exercise and diet impact on gut microbial diversity

Scientists at the Science Foundation Ireland-funded Alimentary Pharmabiotic Centre (APC) at University College Cork and Teagasc Food Research Centre, Moorepark, have carried out a study in conjunction with the Irish Rugby Football Union that has revealed that exercise and associated dietary changes influence gut microbial diversity.

10 Jun 2014

First Edition: June 10, 2014

Today's headlines include details of an extensive, nationwide audit of the wait times for care at VA hospitals and clinics.

10 Jun 2014

X linked News and Research

PD MED trial: Levodopa drug better for long-term treatment of newly diagnosed PD

Fighting off illness causes sleep deprivation and affects memory

Use of opioid linked to higher levels of dissatisfaction following spine surgery

Human mind can rapidly absorb new information by synchronization of brain waves

Adolescents tend to be more powerful in influencing friends to start smoking than to quit

One-third of PsA patients not receiving adalimumab doses to achieve optimal clinical benefit

People with obesity gene FTO tend to gain more weight as they age

Cancer drug offers protection against thrombosis

Exercise transiently suppresses inflammation in rheumatic disease

Study examines effect of phthalate exposure in humans’ sperm epigenetics

Researchers study structural aspects of DNA-particle/lipid interface directly using x-ray scattering

Brain structure linked to psychosis symptoms

Long-term follow-up post bariatric surgery linked with more frequent diabetes remission

Hydrolyzed formula does not lower diabetes linked autoantibodies in infants at risk for type 1 diabetes

Study presents oxytocin as latest treatment target for age-related muscle wasting

Virginia budget plan moving forward without Medicaid expansion

EU-funded project aims to identify potential new targets for cancer therapy

Researchers discover strong genetic risk factor for type 2 diabetes in Latin American patients

Exercise and diet impact on gut microbial diversity

First Edition: June 10, 2014

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