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New method decodes the role of DDX41 protein in preventing double-strand breaks in DNA

There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops.

8 Feb 2022

Study suggests hospitalized COVID-19 patients are at higher risk of neurocognitive decline

In a new study, scientists have evaluated patient-reported and clinically tested neuropsychological problems in both ambulatory (outpatients) and hospitalized COVID-19 patients during the early recovery phase.

8 Feb 2022

Using sugar molecules for in vivo tracking of unlabeled stem cells

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers - made out of sugars - that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Missouri’s war on public health shows extent of national rift

Republican Missouri state Sen. Mike Moon believes that covid-19 vaccinations, especially among children, should cease until the long-term effects are known.

8 Feb 2022

Evidence from a major US metropolitan area on home testing and risk factors for acquisition of SARS-CoV-2 infection

A new study analyzed the risk factors for acquiring COVID-19 in a large, prospective cohort of adult residents in the Boston metropolitan area.

8 Feb 2022

Impact of SARS-CoV-2 infection in pregnant women on maternal and perinatal outcomes

Researchers conducted a retrospective cohort analysis by reviewing medical records of pregnant women to examine the impact of SARS-CoV-2 maternal infection on maternal and perinatal outcomes.

8 Feb 2022

Study identifies lower viral load in the nasopharyngeal samples of patients infected with SARS-CoV-2 Omicron variant

In a new study, researchers determined if the higher transmission rate of the SARS-CoV-2 Omicron variant is due to a higher viral load compared to the Delta variant.

8 Feb 2022

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Researchers demonstrated that an MVA vector expressing the SARS-CoV-2 spike protein was 100% effective in preventing neuroinvasion and brain damage by SARS-CoV-2 in transgenic mice.

8 Feb 2022

Health care paradox: Medicare penalizes dozens of hospitals it also gives five stars

The federal government has penalized 764 hospitals — including more than three dozen it simultaneously rates as among the best in the country — for having the highest numbers of patient infections and potentially avoidable complications.

8 Feb 2022

Winners of the first CERF Medical Engineering Prize for ALS Research announced

The Cullen Education and Research Fund announced the recipients of the first CERF Medical Engineering Prize for ALS Research: Dr. Leigh Hochberg, Dr. Conor Walsh, and Dr. Sabrina Paganoni.

8 Feb 2022

Culinary medicine curriculum has a positive impact on outcomes for patients with type 2 diabetes

A culinary medicine curriculum had a positive impact on certain biometric and diet-related behavioral and psychosocial outcomes among low-income, food-insecure patients with type 2 diabetes participating in a clinic-led food prescription program, according to researchers with The University of Texas Health Science Center at Houston.

8 Feb 2022

Research reveals a possible strategy to prevent B-cell acute lymphoblastic leukemia

Short-term treatment with the drug ruxolitinib prevents B-cell acute lymphoblastic leukemia (B-ALL) in mice that have a genetic predisposition to the disease.

8 Feb 2022

Thermo Fisher Scientific launches rapid environmental PCR testing solution that detects in-air SARS-CoV-2 pathogens

Thermo Fisher Scientific Inc. today announced the launch of a new rapid environmental test to help in the fight against COVID-19. The Thermo Scientific Renvo Rapid PCR Test is the latest solution in the company’s in-air pathogen surveillance product portfolio. The Renvo Rapid PCR Test is performed on air samples collected using the company’s Thermo Scientific AerosolSense Sampler.

From Thermo Scientific™ AerosolSense™ Sampler 8 Feb 2022

Memory B cells induced by mRNA vaccine may help generate antibodies against Omicron

In a recent research article published in the journal of Science Immunology, a team of researchers from Japan performed longitudinal analysis on the cellular composition of receptor-binding domain (RBD) memory B cell subsets and its antibody binding and neutralizing activity against the Beta, Delta, and Omicron variants following the second dose of a messenger ribonucleic acid (mRNA) vaccine.

8 Feb 2022

Assessing the association of COVID-19 and Immunoglobulin A vasculitis in children

In a recent study posted to the Research Square* preprint server, researchers conducted a systematic review to investigate any association between immunoglobulin A (IgA) vasculitis and coronavirus disease 2019 (COVID-19) in children.

8 Feb 2022

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

The fight against the COVID-19 pandemic is an international scientific challenge regarding the search for strategies to fight the viral infection and prevent its damaging consequences.

7 Feb 2022

Genetically informed brain atlases help identify hundreds of genomic loci

An international team of scientists has used atlases of the human brain informed by genetics to identify hundreds of genomic loci. Loci is plural for locus, and in genetics indicates the physical location of a gene or variant on a chromosome.

7 Feb 2022

Investigating taraxerol as a protease inhibitor against SARS-CoV-2

In a recent study posted to the Research Square preprint* server, a team of researchers investigated the toxicity and absorption, distribution, metabolism, and excretion (ADME) characteristics of a potent herbal drug, taraxerol, in the management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The paper is under consideration for publication in the Structural Chemistry journal.

7 Feb 2022

SARS-CoV-2 infection-induced antibodies may last more than 20 months

A recent research letter published in the JAMA demonstrated the prevalence and the longevity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in coronavirus disease 2019 (COVID-19) unvaccinated United States (US) adults recovered from the disease in the long term.

7 Feb 2022

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

In a recent research paper published in the journal Infection, the scientists estimated the transmission and disease severity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and the effectiveness of the current coronavirus disease 2019 (COVID-19) vaccines against the same by conducting a literature review. Further, a meta-analysis was conducted to obtain a numeric estimate of the vaccine effectiveness against the Delta variant.

7 Feb 2022

Research News and Research

New method decodes the role of DDX41 protein in preventing double-strand breaks in DNA

Study suggests hospitalized COVID-19 patients are at higher risk of neurocognitive decline

Using sugar molecules for in vivo tracking of unlabeled stem cells

Missouri’s war on public health shows extent of national rift

Evidence from a major US metropolitan area on home testing and risk factors for acquisition of SARS-CoV-2 infection

Impact of SARS-CoV-2 infection in pregnant women on maternal and perinatal outcomes

Study identifies lower viral load in the nasopharyngeal samples of patients infected with SARS-CoV-2 Omicron variant

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Health care paradox: Medicare penalizes dozens of hospitals it also gives five stars

Winners of the first CERF Medical Engineering Prize for ALS Research announced

Culinary medicine curriculum has a positive impact on outcomes for patients with type 2 diabetes

Research reveals a possible strategy to prevent B-cell acute lymphoblastic leukemia

Thermo Fisher Scientific launches rapid environmental PCR testing solution that detects in-air SARS-CoV-2 pathogens

Memory B cells induced by mRNA vaccine may help generate antibodies against Omicron

Assessing the association of COVID-19 and Immunoglobulin A vasculitis in children

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

Genetically informed brain atlases help identify hundreds of genomic loci

Investigating taraxerol as a protease inhibitor against SARS-CoV-2

SARS-CoV-2 infection-induced antibodies may last more than 20 months

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

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