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Researchers identify DNA methylation in patients with schizophrenia

In a new study, researchers at the Swedish medical university Karolinska Institutet have identified epigenetic changes - known as DNA methylation - in the blood of patients with schizophrenia.

28 Mar 2012

Hyperinsulinemia itself not a cause of atherosclerosis

A number of studies have shown that excess insulin circulating in the bloodstream is a major independent risk factor for cardiovascular disease. However, a new study from Joslin Diabetes Center finds that this condition, called hyperinsulinemia, is itself not a cause of atherosclerosis.

28 Mar 2012

HAART does not completely suppress HIV in sexually active MSM

Researchers from Boston University School of Medicine (BUSM) and Fenway Health have found that highly active antiretroviral therapy (HAART) does not completely suppress HIV in the semen of sexually active HIV-infected men who have sex with men.

28 Mar 2012

North Shore-LIJ's first-ever walking challenge kicks off this week

The North Shore-LIJ Health System's first-ever walking challenge, the Walk to Paris, kicked off this week with 15,000 employees lacing up their sneakers to compete for a free trip to Paris. The fitness challenge is one of many initiatives that the 15-hospital health system has rolled out to improve the health and wellness of its employees.

28 Mar 2012

Pulsed photoacoustic techniques can diagnose different cancer cell types

Researchers have developed multiple techniques and procedures to detect cancer cells during the earliest stages of the disease or after treatment. But one of the major limitations of these technologies is their inability to detect the presence of only a few cancer cells.

28 Mar 2012

Cardiac CT more effective in evaluating ER patients with chest pain

Cardiac computed tomography angiography scans (CT scans that look at the heart) can provide a virtually instant verdict on whether chest pain is from blockage of the coronary arteries.

28 Mar 2012

Roaring snores could be sounds of obstructive sleep apnea

Roaring snores that rumble a room or violent snorts for breath during sleep could be sounds of obstructive sleep apnea. While a true diagnosis is only possible with a sleep study, if left untreated, the sleep disorder could be fatal.

28 Mar 2012

AABB issues new RBC transfusion guidelines

The transfusion of red blood cells is a common treatment in clinical practice. However, the level at which they are transfused varies based not only on a patient's health, but also is determined by what the administering physician deems appropriate. Today, the American Association of Blood Banks (AABB) has issued new guidelines, published in Annals of Internal Medicine, recommending that transfusion of red blood cells be considered at a hemoglobin threshold of 7 to 8 g/dL for stable adults and children.

28 Mar 2012

CABG offers higher survival rates for older adults with CHD than PCI

A new comparative effectiveness study found older adults with stable coronary heart disease (CHD) who underwent bypass surgery had better long-term survival rates than those who underwent a non-surgical procedure to improve blood flow to the heart muscle, also called revascularization.

28 Mar 2012

New gene transfer technique can treat beta-thalassemia, sickle cell anemia

A team of researchers led by scientists at Weill Cornell Medical College has designed what appears to be a powerful gene therapy strategy that can treat both beta-thalassemia disease and sickle cell anemia. They have also developed a test to predict patient response before treatment.

28 Mar 2012

Mount Sinai researchers present 86 abstracts and plenary sessions at ACC meeting

Mount Sinai School of Medicine researchers presented 86 abstracts and plenary sessions at the American College of Cardiology's (ACC) 61st Annual Scientific Session, including ground-breaking research on aggressive statin therapy, the prevalence of unrecognized cardiovascular disease symptoms in women, and morbidity associated with non-adherence to medication after stent implantation. The meeting took place March 23-27, 2012 in Chicago.

28 Mar 2012

UT Southwestern researcher wins prestigious award from International Atherosclerosis Society

Dr. Helen Hobbs, a preeminent researcher on the genetics of cholesterol metabolism at UT Southwestern Medical Center, has won a prestigious award from the International Atherosclerosis Society.

28 Mar 2012

Researchers develop gut-on-a-chip microdevice

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have created a gut-on-a-chip microdevice lined by living human cells that mimics the structure, physiology, and mechanics of the human intestine-even supporting the growth of living microbes within its luminal space.

28 Mar 2012

CRF initiates Harmonizing Outcomes with Revascularization and Stents in AMI II trial

The Cardiovascular Research Foundation (CRF) today announced the initiation of the HORIZONS-AMI II randomized trial, evaluating Promus Element platinum-chromium everolimus-eluting stents versus Omega bare-metal stents in patients with heart attack undergoing primary angioplasty with bivalirudin anticoagulation.

28 Mar 2012

Lower dose of thrombolytics can treat moderate pulmonary embolism

Pulmonary embolism -- the sudden blockage of an artery in the lung -- is estimated to cause over 100,000 deaths each year in the U.S. Although thrombolytics, or "clot-buster" drugs, are currently reserved to treat only the most severe cases of pulmonary embolism, new data suggest that when used at lower doses, these drugs are also safe and effective for more common, moderate cases of pulmonary embolism, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

28 Mar 2012

Chocolate for weight loss: Study

The US survey of a population of more than 1000 adults, published as a research letter in the Archives on Internal Medicine, reinforces the idea that chocolate packs heart healthy benefits, despite its high calorie and sugar content. For the study the participants reported eating chocolate an average of twice a week and exercising an average of 3.6 times a week. Their average age was 57.

27 Mar 2012

Boniva generics receive FDA approval for treatment, prevention of osteoporosis

The U.S. Food and Drug Administration today approved the first generic versions of Boniva (ibandronate) tablets, a once-monthly product to treat or prevent osteoporosis in women after menopause.

27 Mar 2012

Previously unknown mechanism helps intestinal bacteria to affect formation of blood vessels

Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have discovered a previously unknown mechanism which helps intestinal bacteria to affect the formation of blood vessels. The results, which are presented in Nature, may provide future treatments of intestinal diseases and obesity.

27 Mar 2012

Study reveals clinically relevant differences between on pump and off pump bypass

A large randomized trial comparing bypass surgery done with a heart-lung machine (on pump) and without it (off pump) found no differences in results between techniques overall but some clinically relevant differences, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

High-risk, high-cost PCI patients can be identified through pre-procedure bleeding risk score

A pre-procedure bleeding risk score can accurately identify high-risk, high-cost patients and may provide an opportunity to employ bleeding avoidance strategies to improve patient outcomes and reduce total costs related to percutaneous coronary intervention (PCI) procedures, according to a retrospective study being presented March 26 at the 61st annual American College of Cardiology (ACC) scientific session.

27 Mar 2012