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Immunity connects gut microbiota and age-related pathologies

EPFL scientists have discovered how a dysfunction in the immune system can cause an overload of a gut bacterium. The bacterium produces excess lactic acid, which in turn triggers the production of reactive oxygen species that cause damage to cells and many age-related pathologies.

13 Nov 2018

Study uncovers link between gut disruption and aging

A new study has shed light on how the disruption of commensal bacteria within the gut can affect the immune system and lead to age-related pathologies.

13 Nov 2018

Antibiotic resistance data from across the globe released

The World Health Organization (WHO) has released a notification regarding antibiotic usage and resistance this week. The organization has warned that some countries have a very high consumption of antibiotics and there is a shortage in several regions worldwide. This disparity has led to misuse that had spread antibiotic resistance, the WHO says.

13 Nov 2018

Breakthrough research reveals how deadly pneumococcus avoids immune defenses

Scientists at the University of Liverpool have discovered a new and important function of a toxin produced by disease-causing bacteria that could have significant implications for future vaccine design.

12 Nov 2018

Fecal microbiota transplantation effective against ICI-associated colitis

For the first time, transplanting gut bacteria from healthy donors was used to successfully treat patients suffering from severe colitis caused by treatment with immune checkpoint inhibitors.

12 Nov 2018

Saliva-based RNA test could improve ability to accurately identify children with ASD

Newly published research shows that a saliva-based biomarker panel and associated algorithm could improve the ability to accurately identify children with autism spectrum disorder (ASD) in its earliest stages, announced Quadrant Biosciences Inc.

9 Nov 2018

Severe maternal morbidities highly linked to pregnant woman's risk of death

The number of severe maternal morbidities (SMM) a pregnant woman has is highly linked to her risk of maternal death, according to a new study by researchers at ICES and St. Michael's Hospital.

9 Nov 2018

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

A phase 2 clinical trial led by Stephanie N. Taylor, MD, Professor of Medicine and Microbiology in the Section of Infectious Diseases at LSU Health New Orleans School of Medicine, has found that a new antibiotic effectively treats uncomplicated urogenital and rectal gonorrhea infections in a single oral dose.

9 Nov 2018

Bfr organizes symposia for research on viruses and antimicrobial resistance in food chain

Against this background, the German Federal Institute for Risk Assessment is organising two symposia dealing with microbial risks in food in November 2018: "Food-associated viruses" on 7 November and "Antimicrobial resistance in the food chain" on 8/9 November.

9 Nov 2018

Scientists move closer to gonorrhea vaccine after large-scale proteomic study

In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs.

8 Nov 2018

Breastmilk and saliva mixtures regulate oral microbiome of newborn babies

A study led by Dr Emma Sweeney and Adjunct Associate Professor Christine Knox, from QUT's Institute of Health and Biomedical Innovation, with colleagues at the University of Queensland, showed that the growth of some microbes was inhibited for up to 24 hours following breastmilk and saliva mixing.

8 Nov 2018

Small molecules designed to inhibit activity of enzymes in infectious diseases

A multidisciplinary study by the Computer Biochemistry Research Group of the Universitat Jaume I from Castellón, Spain, in collaboration with groups from universities from Canada and the United Kingdom, have designed small molecules that are able to bond with and inhibit the activity of enzymes in infectious diseases.

8 Nov 2018

Scientist wins award for research in the field of commensal microbiota

The winner of the Johanna Duermueller-Bol DBMR Research Award 2018 is Dr. Stephanie Ganal-Vonarburg. As a Senior Scientist, she conducts research in the Gastroenterology / Mucosal Immunology Research Laboratory at Bern University Hospital and at the Department for BioMedical Research at the University of Bern.

8 Nov 2018

Researchers develop technique to disrupt communication between microorganisms

The World Health Organization considers Pseudomonas aeruginosa a germ requiring urgent action to prevent and control its spread. The bacteria can cause a variety of diseases from chronic lung infections to sepsis.

8 Nov 2018

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them.

7 Nov 2018

Slime in showerheads could harbour dangerous lung bacteria finds study

A study has shown that the showerheads contain slime that can be home to potentially dangerous bacteria which lead to severe lung disease. Mycobacterial bacteria are responsible for lung diseases explain experts.

4 Nov 2018

Lymph nodes serve as reservoirs of prolonged bacterial persistence during Mtb infection

Lymph nodes can contain large numbers of tuberculosis-causing bacteria and serve as long-term reservoirs of bacterial persistence, according to a study published November 1 in the open-access journal PLOS Pathogens by JoAnne Flynn of the University of Pittsburgh School of Medicine, and colleagues.

2 Nov 2018

Antibiotic found in dirt can destroy mutant mycobacteria responsible for TB, study suggests

For decades, doctors have been using antibiotics to fight tuberculosis. And consistently, the microbe responsible for the disease, Mycobacterium tuberculosis, has been fighting back. When confronted with current drugs, such as the antibiotic rifamycin, the bacterium often mutates in ways that make it resistant to the treatment.

1 Nov 2018

Tick-borne disease is multiple microbial in nature

A study recently published in Scientific Reports discovered that 65% of Lyme disease patients irrespective of their disease stage respond to several microbes.

1 Nov 2018