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UNC-45A protein plays critical role in breast cancer cell division and migration

Researchers have found that a protein linked to cell division and migration and tied to increased cell proliferation in ovarian tumors is also present at high levels in breast cancer specimens and cell lines. The protein, dubbed "UNC-45A," was also determined to be more active in breast cancer cells than in normal breast cells.

16 Sep 2011

Scientists uncover unknown fail-safe pathway for inherited disorders

Scientists at the University of California, San Diego School of Medicine have uncovered a previously unknown fail-safe (compensatory) pathway that potentially protects the brain and other organs from genetic and environmental threats.

16 Sep 2011

Researchers identify promising new therapies for ependymoma

Researchers have identified promising new therapies for ependymoma, a rare tumor with few treatment options. St. Jude Children's Research Hospital investigators led the effort, which used a new, faster drug development system that combines the latest drug screening technology with the first accurate animal model of the tumor.

16 Sep 2011

Polyplus-transfection appoints ten additional biologists and chemists to support multiple pre-clinical studies

Polyplus-transfection SA, which specializes in the development of innovative solutions for the delivery of nucleic acids in research and therapeutics, today celebrates ten years of continuous growth.

15 Sep 2011

Anavex Life Sciences to present data on lead compound for Alzheimer’s at Japan Neuroscience Society

Anavex Life Sciences Corp. will present the most recent data showing the therapeutic potential of ANAVEX compounds in animal models of Alzheimer’s disease at a special symposium of the 34th annual meeting of the Japan Neuroscience Society. The symposium is being held in Yokohama, Japan from September 15-17, 2011.

15 Sep 2011

Research looks at impact of tougher U.S. teenage driving laws

According to a nationwide survey tougher licensing laws for teenage drivers have reduced deadly accidents among 16-year-olds, but have led to increasing the fatal crash rate among 18-year-olds.

15 Sep 2011

ODAC recommends ApoPharma's Ferriprox for FDA approval to treat transfusional iron overload

ApoPharma Inc. today announced that the Oncologic Drugs Advisory Committee (ODAC) to the U.S. Food and Drug Administration (FDA) voted 10 - 2 to recommend that the FDA grant accelerated approval of Ferriprox (deferiprone), an oral iron chelator, for the treatment of patients with transfusional iron overload when current chelation therapy is inadequate.

15 Sep 2011

Differences in lifestyle, tumor genetics linked to head and neck cancer in African Americans

Why are African Americans more likely than Caucasians to be not only diagnosed with head and neck cancer, but also die from the disease? While the answer isn't a simple one, differences in lifestyle, access to care and tumor genetics may, in part, be to blame, according to a new study from Henry Ford Hospital.

15 Sep 2011

Uterine stem cells could help treat diabetes

Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published in the journal Molecular Therapy.

15 Sep 2011

Sickle cell trait does not increase risk of severe kidney disease in African-Americans

Researchers at Wake Forest Baptist Medical Center report that sickle cell trait is not a risk factor for the development of severe kidney disease in African-Americans.

15 Sep 2011

Rac1 protein triggers growth of long 'legs' that could propel melanoma cells to spread

Cancer Research UK scientists have discovered that a protein called Rac1 prompts pigment cells to sprout long 'legs' that could propel skin cancer cells, allowing them to spread, according to research published in Developmental Cell today.

15 Sep 2011

Psychological stress of racial discrimination may contribute to health disparities

The consequences of psychological stress, resulting from racial discrimination, may contribute to racial health disparities in conditions such as cardiovascular disease, diabetes and other age-associated diseases.

15 Sep 2011

Researchers discover several chemical compounds against human prion diseases

In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening the door to potential treatments for human prion diseases.

15 Sep 2011

SARcode Bioscience initiates enrollment in SAR 1118 Phase 3 study for dry eye disease

SARcode Bioscience, Inc., a privately-held biopharmaceutical company, announced today that the initial patient has been enrolled in the company's pivotal Phase 3 clinical study (OPUS-1) of SAR 1118 ophthalmic solution.

15 Sep 2011

Glucose metabolism inhibition with 2-DG induces cell death in alveolar rhabdomyosarcoma

A study made by IDIBELL researchers shows that glucose metabolism inhibition with 2-deoxyglucose (2-DG) induces cell death in a type of childhood sarcoma: alveolar rhabdomyosarcoma.

15 Sep 2011

New Zealand biotechnology company moves to US

Today leading New Zealand biotechnology company Therapy Cell Ltd announced it was moving to the United States through its merger with Therapy Cells Inc (formerly DIII OTC Market). This exciting Bio Tech/Med tech Company holds the exclusive technology that allows adult cells from a specific tissue (e.g. Achilles tendon) to grow again from an individual to enact repair and regeneration of that tissue.

14 Sep 2011

Natural killer white blood cells caught on film

Scientists reveal in more detail than ever before how white blood cells kill diseased tissue using deadly granules, in research published today in PLoS Biology.

14 Sep 2011

DiscoveryBioMed receives NIDDK grant for Cystic Fibrosis Corrector Ligand Drug Discovery program

DiscoveryBioMed, Inc. (DBM), a human cell-based drug discovery company, learned recently that its Cystic Fibrosis Corrector Ligand (CFCL) Drug Discovery program will be funded by the NIH. The two-year award will focus on validation and prioritization of several lead CFCL chemical classes, drugs that correct the most common cystic fibrosis (CF) disease-causing mutation.

14 Sep 2011

Celecoxib inhibits GSK3 enzyme in lung cancer cells

Several clinical studies have shown that taking the anti-inflammatory drug celecoxib can reduce the risk of developing polyps that lead to colon cancers, at the cost of increasing the risk of heart disease. But what if this tradeoff was not necessary?

14 Sep 2011

Single UV laser pulse simultaneously zaps away biological tissue at multiple points

Researchers at Vanderbilt University have developed a new technique that uses a single UV laser pulse to zap away biological tissue at multiple points simultaneously, a method that could help scientists study the mechanical forces at work as organisms grow and change shape.

14 Sep 2011

B Cell News and Research

UNC-45A protein plays critical role in breast cancer cell division and migration

Scientists uncover unknown fail-safe pathway for inherited disorders

Researchers identify promising new therapies for ependymoma

Polyplus-transfection appoints ten additional biologists and chemists to support multiple pre-clinical studies

Anavex Life Sciences to present data on lead compound for Alzheimer’s at Japan Neuroscience Society

Research looks at impact of tougher U.S. teenage driving laws

ODAC recommends ApoPharma's Ferriprox for FDA approval to treat transfusional iron overload

Differences in lifestyle, tumor genetics linked to head and neck cancer in African Americans

Uterine stem cells could help treat diabetes

Sickle cell trait does not increase risk of severe kidney disease in African-Americans

Rac1 protein triggers growth of long 'legs' that could propel melanoma cells to spread

Psychological stress of racial discrimination may contribute to health disparities

Researchers discover several chemical compounds against human prion diseases

SARcode Bioscience initiates enrollment in SAR 1118 Phase 3 study for dry eye disease

Glucose metabolism inhibition with 2-DG induces cell death in alveolar rhabdomyosarcoma

New Zealand biotechnology company moves to US

Natural killer white blood cells caught on film

DiscoveryBioMed receives NIDDK grant for Cystic Fibrosis Corrector Ligand Drug Discovery program

Celecoxib inhibits GSK3 enzyme in lung cancer cells

Single UV laser pulse simultaneously zaps away biological tissue at multiple points

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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