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New discovery on how botulism paralyzes nerve cells

New structures of a botulism toxin interacting with a mimic of the nerve-cell protein it destroys suggest new ways to block this often-fatal interaction. Indeed, the mimic molecules have such high affinity for the toxin and bind to it so tightly that they themselves could possibly serve as anti-toxin drugs with further modification, the researchers said.

21 Jun 2009

Some call for more action at conclusion of Pacific Health Summit

Some Pacific Health Summit attendees said more action should have come from the tuberculosis-focused conference, which ended on Thursday in Seattle, Seattle Times' "Business of Giving" blog reports.

21 Jun 2009

Tibotec, TB Alliance join to expedite development of promising tuberculosis drug

The pharmaceutical company Tibotec said it will join with the non-profit Global Alliance for Tuberculosis Development (TB Alliance) to speed up the development of the experimental TB drug TMC207, Health-e/IOL reports (Thom, Health-e/IOL, 6/18). Tibotec, which is a subsidiary of Johnson & Johnson, announced the news on Wednesday at the Pacific Health Summit in Seattle (Doughton, Seattle Times, 6/18).

18 Jun 2009

Seattle Genetics starts trial of SGN-35 for anaplastic large cell lymphoma

Seattle Genetics, Inc. (NASDAQ:SGEN), has announced that it has initiated a phase II clinical trial of SGN-35 for patients with relapsed or refractory systemic anaplastic large cell lymphoma (ALCL). SGN-35 is an antibody-drug conjugate (ADC) that utilizes Seattle Genetics’ proprietary technology to empower antibodies by linking them to potent cell-killing drugs.

18 Jun 2009

New antioxidant supplement may help slow sight loss in elderly

Queen's University Belfast academics have helped develop an antioxidant supplement which may slow down sight loss in elderly people.

18 Jun 2009

Scientists edit genes in human stem cells

Researchers at the Johns Hopkins School of Medicine have successfully edited the genome of human- induced pluripotent stem cells, making possible the future development of patient-specific stem cell therapies. Reporting this week in Cell Stem Cell, the team altered a gene responsible for causing the rare blood disease paroxysmal nocturnal hemoglobinuria, or PNH, establishing for the first time a useful system to learn more about the disease.

18 Jun 2009

Can the private sector deliver public services?

The private sector has an important role to play in the delivery of public services, according to a new report by Professor Paul Grout of the Centre for Market and Public Organisation (CMPO). However, he argues that the desire to be profitable can be damaging in some cases, generally in public services where staff are motivated, not just by financial reward, but also by a desire to serve the greater public good.

18 Jun 2009

Support Tasmania with telecare

On 30 April 2009, Tunstall Healthcare and Alzheimer's Australia Tasmania launched 'Telecare in Tasmania', a new respite facility fitted out with a range of Tunstall's assistive technologies, where people can come and try out the technology for themselves.

18 Jun 2009

Rapid prototyping of new tissues and organs

A more effective way to build plastic scaffolds on which new tissues and even whole organs might be grown in the laboratory is being developed by an international collaboration between teams in Portugal and the UK.

18 Jun 2009

CNN, The Independent, VOA News examine technology, health systems in developing countries

CNN examines the increasing numbers of health workers using cell phone technology to monitor diseases in the developing world. The article features EpiSurveyor - "a free, open-source application designed for personal digital assistants" that can be downloaded onto cell phones, so that officials can "gather data directly from the site of the outbreak and send it electronically back to headquarters for faster analysis," CNN writes.

18 Jun 2009

Whole-genome searches unlock secrets of a childhood cancer

Two new studies from The Children's Hospital of Philadelphia advance the search for genetic events that result in neuroblastoma, a puzzling, often-deadly type of childhood cancer.

17 Jun 2009

Taxol-carrying nanoparticles

Nanoparticles specially engineered by University of Central Florida Assistant Professor J. Manuel Perez and his colleagues could someday target and destroy tumors, sparing patients from toxic, whole-body chemotherapies.

17 Jun 2009

Minimally invasive treatment of brain tumors on the horizon

Duke University engineers have taken a first step toward a minimally invasive treatment of brain tumors by combining chemotherapy with heat administered from the end of a catheter.

17 Jun 2009

G.E. offers loans for e-health record purchases

"General Electric Co. said its GE Capital division will make no-interest loans to hospitals and health-care providers that purchase GE's health-care information technology," The Wall Street Journal reports.

17 Jun 2009

Telehealth interventions for the secondary prevention of coronary heart disease

The use of phone and internet between patients and healthcare providers is an effective way to reduce risk factors for coronary heart disease and the risk of further events after a heart attack, according to new research published today in the June issue of the European Journal of Cardiovascular Prevention & Rehabilitation.

16 Jun 2009

Plant microbe shares features with drug-resistant pathogen - implications for biotech

An international team of scientists has discovered extensive similarities between a strain of bacteria commonly associated with plants and one increasingly linked to opportunistic infections in hospital patients. The findings suggest caution in the use of the plant-associated strain for a range of biotech applications. The genetic analysis was conducted in part at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, and will be published in the July 2009 issue of Nature Reviews Microbiology, now available online.

16 Jun 2009

Expert physician on “meaningful use” guidelines

Jonathan Teich, M.D., is the Chief Medical Informatics Officer (CMIO) at Elsevier, the world's largest publisher of scientific, technical and medical information. He is also an assistant professor of medicine at Harvard Medical School and a board-certified attending physician in emergency medicine at Brigham & Women's Hospital, Boston.

16 Jun 2009

Dilon Technologies delivers enhanced imaging capabilities

Dilon Technologies, Inc., the leader in molecular breast imaging, today announced the release of the newest Dilon 6800 Software update including enhancements for both breast and general nuclear medicine applications image processing. The new software functionalities complement the Slant15 Collimator for breast imaging and the Low Energy High-Resolution (LEHR) Collimator for general nuclear medicine applications, both released earlier this year as purchase options for the Dilon 6800 gamma camera.

16 Jun 2009

Genomic discovery: Protecting kidney function during heart failure

Mayo Clinic cardiology researchers have found a peptide that helps preserve and improve kidney function during heart failure, without affecting blood pressure. Earlier variations of this peptide caused blood pressure to drop limiting the potential benefits to the kidneys. The findings appear in the current Proceedings of the National Academy of Sciences.

16 Jun 2009

Physicians wait for health IT guidelines, officials want 'every doctor's office' online

Physicians are still waiting for clear cut rules for how they must use health information technology in order to be eligible for economic stimulus-funded incentives, American Medical News, a publication of the American Medical Association, reports.

15 Jun 2009