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Gene subnetworks provide new prognostic markers for breast cancer

The metastasis or spread of breast cancer to other tissues in the body can be predicted more accurately by examining subnetworks of gene expression patterns in a patient's tumor, than by conventional gene expression microarrays, according to a presentation at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

15 Dec 2008

Colonoscopy significantly reduces death from left-sided colon cancer but not from right-sided

A new study finds that colonoscopy is strongly associated with fewer deaths from colorectal cancer.

15 Dec 2008

Breast cancer genome shows instability of cancer

A newly published genome sequence of a breast cancer cell line reveals a heavily rearranged genetic blueprint involving breaks and fusions of genes and a broken DNA repair machinery, said researchers at Baylor College of Medicine in a report that appears online in the journal Genome Research.

15 Dec 2008

Mouse model shows blood stem cells in action

Over a period of five years, scientists at the Johannes Gutenberg University Mainz have managed to create a genetically modified mouse in which the activity of the blood stem cells can be tracked.

15 Dec 2008

Lumbar fusion shows long-term benefits

Lumbar fusion is becoming an increasingly common treatment for low-back pain, but its long-term effects are relatively unknown. A doctoral thesis from the Swedish medical university Karolinska Institutet now shows that the long-term effects are superior to those of physiotherapy.

15 Dec 2008

Sarcasm - a diagnostic tool for dementia

Scientists say sarcasm, sometimes referred to as the lowest form of wit, might be a useful tool in diagnosing a certain type of dementia.

15 Dec 2008

Roche's new dual-target HIV-1 test approved in Europe

Roche announced today that its innovative dual-target HIV-1 test has received CE Mark certification, allowing it to be sold for clinical use in the European Union. The COBAS AmpliPrep/COBAS TaqMan HIV-1 Test, v2.0 utilizes a unique design to simultaneously amplify and detect two separate regions of the HIV-1 genome.

15 Dec 2008

Lung cancer screening feasibility study funded

A study to assess the feasibility of undertaking a UK-based screening trial for lung cancer has been commissioned by the National institute for Health Research Health Technology Assessment (NIHR HTA) programme. Lung cancer kills more people worldwide than any other malignancy accounting for around 1.4 million deaths each year, and around 38,000 individuals are diagnosed with the disease in the UK each year.

15 Dec 2008

Computer-aided detection (CAD) mammography for breast cancer screening

Computer programs designed to help radiologists could identify more cases of breast cancer, but they might also increase the number of false-positive results, which can lead to biopsies in healthy women, according to a recent systematic review.

15 Dec 2008

Study reveals clues to how we forget over short-term

Even though forgetting is such a common occurrence, scientists have not reached a consensus as to how it happens.

14 Dec 2008

Exparel (DepoBupivacaine) shows promise in hernia repair

A Phase II trial of a single intraoperative administration of Exparel (DepoBupivacaine) resulted in significantly reduced pain with activity in the first 8 to 24 hours following surgery, when pain is generally greatest, compared to conventional treatment.

14 Dec 2008

Carbon nanotube sensors for cancer drugs

MIT engineers have developed carbon nanotubes into sensors for cancer drugs and other DNA-damaging agents inside living cells.

14 Dec 2008

Promising clinical trial for Progeria "premature aging" disease

One of the fastest translations of a basic research discovery into a promising clinical trial for an "untreatable" and fatal disorder will be discussed publicly for the first time by the key players in this remarkable research story, on Sunday, Dec. 14, at the American Society for Cell Biology (ASCB)'s annual meeting in San Francisco.

14 Dec 2008

New imaging system with higher resolution

Applied Precision, Inc. a leading provider of imaging, measurement, and analysis systems for the life sciences industries announced that it will introduce a new imaging system at the American Society for Cell Biology (ASCB) annual conference with twice the resolution of traditional microscopes.

14 Dec 2008

Novavax announces positive results in trial of seasonal influenza VLP (trivalent) vaccine candidate

Novavax, Inc. has announced favorable results from a Phase IIa human clinical trial of its seasonal influenza VLP (trivalent) vaccine candidate.

12 Dec 2008

New Georgia initiative to improve rural hospitals

Seven rural Georgia hospitals will participate in a new initiative designed to help increase their capacity to serve patients, improve the quality of their services and reduce costs.

12 Dec 2008

Mathematical models of adaptive immunity

More than five million people die every year from infectious diseases, despite the availability of numerous antibiotics and vaccines. The discovery of penicillin to treat bacterial infections, along with the development of vaccines for previously incurable virus diseases such as polio and smallpox, achieved great reductions in mortality during the mid-20th century.

11 Dec 2008

University at Buffalo driver simulation study targets high-risk teen drivers

Using the bells and whistles of a state-of-the-art entertainment arcade, a University at Buffalo Graduate School of Education project aims to improve the driving habits of teenagers at the very top of the risk pool, and at the same time bring child and parent together for a happier, better functioning family.

11 Dec 2008

Panel blasts Bush administration's nanotech risk strategy

A National Research Council (NRC) committee has issued a highly critical report describing serious shortfalls in the Bush administration's strategy to better understand the environment, health and safety (EHS) risks of nanotechnology and to effectively manage those potential risks.

10 Dec 2008

New technique may provide quicker and easier way of developing protein-based drugs

Research by a Michigan State University chemist could eventually lead to a quicker and easier way of developing protein-based drugs that are key to treating a number of diseases, including cancer, diabetes and hepatitis.

10 Dec 2008