Therapy News and Research

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Tuberculosis therapy in HIV-infected patients

In a retrospective study of 700 patients with culture-positive tuberculosis (TB), relapse rates were found to be significantly higher in HIV-infected patients compared to HIV-uninfected patients following a rifamycin-based regimen.

3 Jun 2007

Real-time, direct MRI monitoring of vector distribution within the brain

A team of scientists, led by Dr. Krystof Bankiewicz, University of California-San Francisco, presented this significant advance, which allows, for the first time, to adjust parameters of vector infusion while delivering gene therapy, giving surgeon full control over gene transfer technology.

3 Jun 2007

Directly observed HIV therapy for children is promising

Directly observed antiretroviral therapy is a promising strategy to ensure that HIV-infected children in developing countries take life-saving medications, new research from The Warren Alpert Medical School of Brown University shows.

3 Jun 2007

Research explains why those with obstructive sleep apnea are at higher risk for cardiovascular disease

Researchers have found that patients with obstructive sleep apnea (OSA) have higher levels of a type of dead cells (apoptotic cells) from the lining (endothelium) of their blood vessels circulating in their bloodstream than people who do not have OSA.

3 Jun 2007

C-reactive protein identified as marker for prostate cancer survival

Oregon Health & Science University Cancer Institute researchers have identified a protein that is a strong indicator of survival for men with advanced prostate cancer.

3 Jun 2007

Novel technologies show promise for future of gene transfer

Several new technologies that could significantly impact the future of gene transfer applications were presented at a conference at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

New platform for regulating the expression of therapeutic genes

A new platform for regulating the expression of therapeutic genes, which will have major implications for gene and cell therapy, was presented at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

Nanoparticle delivery of insulin gene to fight juvenile diabetes developed

A safer method to deliver the insulin gene to diabetes patients using nanoparticles, was presented at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

Longer CPAP use at night can normalize one's daytime functioning

A study published in the June 1st issue of the journal SLEEP finds that longer nightly duration of continuous positive airway pressure (CPAP) use can help those suffering from obstructive sleep apnea (OSA) achieve normal daytime functioning.

3 Jun 2007

Genetic testing helps cancer survivors fight for their loved ones

Family members of those who are successfully fighting cancer are protecting themselves and their families from the disease through genetic testing and hereditary cancer risk assessment.

3 Jun 2007

FDA approves Norditropin for short stature in children with Noonan syndrome

Novo Nordisk has announced that Norditropin (somatropin[rDNA origin] injection) received U.S. Food and Drug Administration (FDA) approval for the treatment of short stature in children with Noonan syndrome.

3 Jun 2007

New discoveries on genes implicated in Fanconi anaemia

An international research consortium, which included the participation of the Mutagnesi Group from the UAB, has made outstanding progress in the study of Fanconi anaemia.

3 Jun 2007

Brain inflammation may actually be a friend for Alzheimer's patients

Inflammation in the brain may not be so bad after all when it comes to Alzheimer's disease.

3 Jun 2007

Blood test may help signal tumor's remission, return in throat cancer patients

A blood test that detects proteins commonly released by a growing tumor could one day become a useful tool for monitoring the effectiveness of chemotherapy and radiation treatment in people with advanced throat cancer, according to a study published in the June 1, 2007, issue of Clinical Cancer Research .

3 Jun 2007

Adding medication improves recovery for elderly with depression

Adding a medication to a standard treatment regimen for major depressive disorder in the elderly improves chances of recovery in those who do not adequately respond to the first-course therapy or who relapse from it, finds a University of Pittsburgh School of Medicine study published in the June issue of the American Journal of Psychiatry, the official journal of the American Psychiatric Association.

3 Jun 2007

Study questions risks of aprotinin during heart surgery

Contrary to recent studies, proper use of a drug called aprotinin to reduce bleeding during heart surgery does not increase the risk of heart attack or stroke, according to a study in the June issue of The Journal of Thoracic and Cardiovascular Surgery.

1 Jun 2007

Surgery best for degenerative spondylolisthesis with spinal stenosis

In one of the three most common back conditions for which patients seek treatment, surgery proved to have substantially better results than non-surgical remedies, according to Dartmouth-led research published in the May 31 New England Journal of Medicine.

1 Jun 2007

Exercise helps maintain muscle in elderly

Why do older people tend to lose muscle mass and grow frail?

1 Jun 2007

Once-fatal metabolic disorders treatable

People with a class of rare genetic disorders that often lead to brain damage, coma and death can be successfully treated with drugs, says a researcher at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

1 Jun 2007

New tests for leishmaniasis and leprosy

The Seattle-based Infectious Disease Research Institute (IDRI) and Chembio Diagnostics, Inc. have entered into two research and development agreements for the development of rapid diagnostic tests for Leishmaniasis and Leprosy, two "neglected diseases" targeted by IDRI.

1 Jun 2007