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Long-term ulcerative colitis study shows Remicade responders maintained improvement

Findings presented at Digestive Disease Week 2007 (DDW), from long-term extensions of the ACT trials (Active Ulcerative Colitis 1 & 2) show that subjects with moderately to severely active ulcerative colitis (UC) who had responded to REMICADE (infliximab) in the blinded phase of the trials maintained improvement in their clinical symptoms for up to two years.

24 May 2007

Gene therapy used to reverse heart failure in animals

Heart researchers at the Center for Translational Medicine at Jefferson Medical College have used gene therapy to reverse heart failure in animals.

24 May 2007

Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid

Researchers at Weill Cornell Medical College have gotten much closer to understanding how immune-based therapies can treat Alzheimer's disease -- by studying how antibodies go inside brain cells to reduce levels of Alzheimer's-linked amyloid peptides that form plaques between neurons.

24 May 2007

New adult nerves have a deeper role than simply replacing dead ones

You may not be able to relive your youth, but part of your brain can. Johns Hopkins researchers have found that newly made nerves in an adult brain's learning center experience a one-month period when they are just as active as the nerves in a developing child.

24 May 2007

Pure oxygen harms the brain

A paramedic or doctor plops a mask over the face of a person struggling to breathe and begins dispensing pure oxygen.

24 May 2007

University of Alabama at Birmingham opens adult Down Syndrome clinic

UAB (University of Alabama at Birmingham) has opened one of the few clinics in the nation dedicated to providing services to adult patients with Down Syndrome.

24 May 2007

Effects of estrogen therapy with perimenopausal women

When is the best time in a woman's reproductive history to start hormone therapy? How does estrogen therapy affect a woman's cognition and mood? What is the most beneficial form of estrogen?

24 May 2007

Breakthrough in understanding how cancers spread

The University of Manchester study used embryonic stem (ES) cells to investigate how some tumours are able to migrate to other parts of the body, which makes the treatment of cancer much more difficult.

From The University of Manchester 24 May 2007

Veterans with extreme mixed handedness and high combat exposure five times more likely to have PTSD

A recent study conducted by investigators with the Geisinger Center for Health Research shows a clear link between combat veterans' use of both hands for common tasks and the likelihood that they will experience post-traumatic stress disorder (PTSD).

24 May 2007

Groundbreaking research on type 1 congenital myotonic dystrophy

Each year, the parents of an estimated one in 20,000 newborns are shocked to learn their child has type 1 congenital myotonic dystrophy (CDM1), a progressive and crippling genetic disorder.

24 May 2007

Minimally invasive device for treating recurrent stress urinary incontinence in women, safe and effective

A minimally invasive device for treating recurrent stress urinary incontinence in women has been shown to be safe and effective in early clinical trials and is now under review by the U.S. Food and Drug Administration (FDA), says Emory University School of Medicine urologist and trial co-principal investigator Niall Galloway, MD.

24 May 2007

New understanding of how immune-based therapies can treat Alzheimer's disease

24 May 2007

Novel preclinical gene therapy approach for treating Niemann-Pick disease

Genzyme Corp. has announced the publication of a new study in The Proceedings of the National Academy of Sciences describing a novel preclinical gene therapy approach for treating Niemann-Pick disease.

24 May 2007

Efficacy and safety of Aripiprazole as adjunctive therapy in major depressive disorder

In adults with major depressive disorder, adding aripiprazole to antidepressant therapy (ADT) resulted in significant improvement in the primary endpoint, the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score.

24 May 2007

Diagnostic tests for Malaria are often underused in Zambia

Despite improvements in the ability to diagnose malaria, these diagnostic tests are often underused in Zambia, and patients with negative test results are often prescribed anti-malaria medications, according to a study in the May 23/30 issue of JAMA , a theme issue on malaria.

24 May 2007

SYMBICORT trial shows improved quality of life with asthma

New data demonstrated that the combination asthma therapy, SYMBICORT (budesonide/formoterol fumarate dihydrate), led to significant improvements in health-related quality of life (HRQL) and greater patient-reported satisfaction with asthma treatment, versus its monocomponents (budesonide or formoterol) or placebo.

24 May 2007

COX inhibitors may weaken protective qualities of estrogen therapy

Researchers from the University of Pennsylvania School of Medicine found in a database study of women heart patients that COX inhibitors such as traditional nonsteroidal anti-inflammatory drugs (NSAIDs) may undermine any purported protection against heart disease in participants taking estrogen therapy.

24 May 2007