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MSK begins CAR T cell clinical trial for children with relapsed or treatment-resistant ALL

Researchers from Memorial Sloan Kettering Cancer Center are pioneering a new groundbreaking clinical trial for children and young adults with relapsed or treatment-resistant acute lymphocytic leukemia (ALL) by using one of the most promising methods of cancer treatment today, chimeric antigen receptor (CAR) T cells.

12 Apr 2015

New study could hold key to control growth of cancer cells

A new study by researchers at the Technion-Israel Institute of Technology could hold a key to control cancer cell growth and development. In a paper published yesterday in CELL, the team reports on the discovery of two cancer-suppressing proteins.

12 Apr 2015

New combination therapy holds promise for treating HER2-positive breast cancer

Resistance to therapy is a major problem in the cancer field. Even when a treatment initially works, the tumors often find ways around the therapy.

10 Apr 2015

Making small changes to protein- and carbohydrate-rich foods is associated with weight loss

Making small, consistent changes to the types of protein- and carbohydrate-rich foods we eat may have a big impact on long-term weight gain, according to a new study led by researchers at the Friedman School of Nutrition Science & Policy at Tufts University.

10 Apr 2015

Fraunhofer researchers develop cell-free substrate made of advanced fibers

Regenerative medicine uses cells harvested from the patient's own body to heal damaged tissue. Fraunhofer researchers have developed a cell-free substrate containing proteins to which autologous cells bind and grow only after implantation.

10 Apr 2015

Stem cell disease model reveals how tumor suppressor may drive bone cancer

Using induced pluripotent stem cells (iPSCs), a team led by Mount Sinai researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver of risk for bone cancers, where the survival rate has not improved in 40 years despite treatment advances.

10 Apr 2015

Winners of GSA poster awards announced at 56th Annual Drosophila Research Conference

The Genetics Society of America (GSA) and the Drosophila research community are pleased to announce the winners of the GSA poster awards at the 56th Annual Drosophila Research Conference, which took place in Chicago, IL, March 4-8, 2015.

10 Apr 2015

Newly approved drug for rare blood cancer shows sustained benefit for 2 years

The most recent results from a clinical trial show that ibrutinib, a newly approved drug for Waldenstrom's Macroglobulinemia, continued to control the rare blood cancer, with 95 percent of patients surviving for two years, report investigators from Dana-Farber Cancer Institute.

10 Apr 2015

Protein-degrading enzyme can trigger strong allergic reactions through skin

Papain is an important industrial protein-degrading enzyme that is used, for example, in the food and cosmetic industries.

10 Apr 2015

Administration of selenide protects heart tissue post cardiac arrest, shows study

Damage to heart muscle from insufficient blood supply during cardiac arrest and reperfusion injury after blood flow is restored can be reduced by nearly 90 percent if selenide, a form of the essential nutrient selenium, is administered intravenously in the wake of the attack, according to a new preclinical study by researchers at Fred Hutchinson Cancer Research Center.

10 Apr 2015

Changing the size and number of pores in processed foods can reduce salt intake

Two University of Illinois food scientists have learned that understanding and manipulating porosity during food manufacturing can affect a food's health benefits.

10 Apr 2015

Scientists identify chemical compounds that block cancer-causing oncoprotein

A team of scientists at the University of Kansas has pinpointed six chemical compounds that thwart HuR, an "oncoprotein" that binds to RNA and promotes tumor growth.

10 Apr 2015

Research opens door to potential drug target for deadly Ebola virus

Opening the door to potential treatments for the deadly Ebola virus, scientists have found that a protein made by the virus plays a role similar to that of a coat-check attendant.

9 Apr 2015

UAB scientists create alternative to the use of viruses in gene therapy

A team of scientists from the Institute for Biotechnology and Biomedicine at the UAB has produced an alternative to the use of viruses in gene therapy. The researchers synthesised nanoparticles which act as artificial viruses, capable of surrounding DNA fragments and releasing them as therapeutic agents, with no biological risk, into the interior of the cells.

9 Apr 2015

Vanderbilt researchers join multi-center effort to accelerate development of potential Ebola therapy

Vanderbilt University researchers have joined a multi-center effort led by Pennsylvania-based Inovio Pharmaceuticals Inc. to accelerate development of potential antibody therapies against the often-lethal Ebola virus.

9 Apr 2015

Neuro-oncology researchers identify mechanism responsible for tumor cell invasion in glioblastoma

A neuro-oncology research team at Dartmouth's Norris Cotton Cancer Center, led by the Director Mark A. Israel, MD with first author Gilbert J. Rahme, PhD, recently identified the transcription factor Id4 as a suppressor of tumor cell invasion in glioblastoma.

9 Apr 2015

Clearer understanding of ORC offers new insight into fundamental DNA replication initiation mechanisms

A clearer understanding of the origin recognition complex (ORC) - a protein complex that directs DNA replication - through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.

9 Apr 2015

Yale University-led research explores directional cues that influence cancer cells

Scientists are mapping the habits of cancer cells, turn by microscopic turn. Using advanced technology and an approach that merges engineering and medicine, a Yale University-led team has compiled some of the most sophisticated data yet on the elaborate signaling networks directing highly invasive cancer cells. Think of it as a digital field guide for a deadly scourge.

9 Apr 2015

Plymouth researchers receive grant to develop effective therapy for Huntington's disease

Huntington's disease is an hereditary disorder of the nervous system caused by a faulty gene on chromosome four. The faulty gene leads to nerve damage in the area of the brain resulting in gradual physical, mental and emotional changes. Those born to a parent with Huntington's disease have a 50:50 chance of developing it, and there is currently no cure.

9 Apr 2015

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers from the School of Medicine at The University of Texas Health Science Center at San Antonio today revealed the molecular structure of the cytotoxin from Mycoplasma pneumoniae, a widespread, highly contagious bacterium that infects the lungs.

8 Apr 2015

G Protein News and Research

MSK begins CAR T cell clinical trial for children with relapsed or treatment-resistant ALL

New study could hold key to control growth of cancer cells

New combination therapy holds promise for treating HER2-positive breast cancer

Making small changes to protein- and carbohydrate-rich foods is associated with weight loss

Fraunhofer researchers develop cell-free substrate made of advanced fibers

Stem cell disease model reveals how tumor suppressor may drive bone cancer

Winners of GSA poster awards announced at 56th Annual Drosophila Research Conference

Newly approved drug for rare blood cancer shows sustained benefit for 2 years

Protein-degrading enzyme can trigger strong allergic reactions through skin

Administration of selenide protects heart tissue post cardiac arrest, shows study

Changing the size and number of pores in processed foods can reduce salt intake

Scientists identify chemical compounds that block cancer-causing oncoprotein

Research opens door to potential drug target for deadly Ebola virus

UAB scientists create alternative to the use of viruses in gene therapy

Vanderbilt researchers join multi-center effort to accelerate development of potential Ebola therapy

Neuro-oncology researchers identify mechanism responsible for tumor cell invasion in glioblastoma

Clearer understanding of ORC offers new insight into fundamental DNA replication initiation mechanisms

Yale University-led research explores directional cues that influence cancer cells

Plymouth researchers receive grant to develop effective therapy for Huntington's disease

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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