Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Mice exposed to fungicide tolyfluanid show metabolic changes

Mice exposed to the fungicide tolyfluanid (TF) showed metabolic changes similar to those that signify the development of the metabolic syndrome. The results, which were presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

24 Jun 2014

Researchers develop GI microbiome modulators to treat prediabetes and diabetes

In adults with prediabetes, a new drug that alters microbial populations and their environment in the gastrointestinal (GI) tract improves glucose tolerance-the body's response to consuming carbohydrates- after four weeks of treatment and without a change in diet.

24 Jun 2014

Adults with Type 2 diabetes achieve better blood glucose control after sleeve gastrectomy surgery

Adults with Type 2 diabetes achieve better blood glucose (sugar) control two years after undergoing laparoscopic sleeve gastrectomy than do patients who receive standard medical diabetes care without this weight loss surgery, a new study finds.

23 Jun 2014

Soy protein supplements do not reduce testosterone levels in men with Type 2 diabetes

Soy protein supplements, which contain natural estrogens, do not reduce testosterone levels in men with Type 2 diabetes who already have borderline-low testosterone, according to a new study.

23 Jun 2014

70% of adults with Type 1 diabetes never use blood glucose self-monitoring devices to download historical data

Almost 70 percent of adults with Type 1 diabetes never use their blood glucose self-monitoring devices or insulin pumps to download historical data about their blood sugar levels and insulin doses-information that likely would help them manage their disease better.

23 Jun 2014

Study explores new ways to improve medications to treat type 2 diabetes

A better understanding of how the transcription factor Peroxisome Proliferator-Activated Receptor Gamma (PPARgamma) works is critical to find new ways to improve medications to treat type 2 diabetes.

23 Jun 2014

Women who develop gestational diabetes perform worse on cognitive function tests

Women who develop diabetes during pregnancy, called gestational diabetes, perform worse on cognitive function tests than do women with a normal pregnancy, according to a new study from Turkey.

23 Jun 2014

Long-term mild cold exposure can stimulate brown fat growth

Long-term mild cold exposure can stimulate brown fat growth and activity in humans and may benefit glucose and energy metabolism, a new study finds.

23 Jun 2014

Researchers shown how free radicals contribute to fatty liver disease

An international team of scientists led by Monash University researchers has shown how free radicals contribute to type 2 diabetes, obesity and fatty liver disease.

23 Jun 2014

African American women respond differently to anti-inflammatory effect of aspirin than white women

African American women respond differently to the anti-inflammatory effect of aspirin than do white American women, new research finds.

23 Jun 2014

Greenlander study identifies single mutation with large diabetes risk

Researchers have used a Greenlandic cohort to identify a genetic mutation whose effect on the risk of diabetes is “several times larger” than any previously discovered.

20 Jun 2014

Telephone-based weight loss intervention is effective in breast cancer treatments

A series of simple telephone calls can make a profound difference in helping women to meet their treatment goals for breast cancer, according to a randomized trial of women who are also obese, published online today in Journal of Clinical Oncology by Dr. Pamela Goodwin of Mount Sinai Hospital and the Lunenfeld-Tanenbaum Research Institute.

20 Jun 2014

Continuation of metformin after cirrhosis diagnosis improves survival rates in diabetes patients

Researchers at Mayo Clinic released a new study reversing current thought on the treatment of cirrhotic patients with type 2 diabetes.

20 Jun 2014

New research reveals gene's role in type 1 diabetes

New research describes details of how a diabetes-related gene functions on a biological pathway that affects the release of insulin. The study authors say that finding drugs that act on that pathway may eventually lead to a new treatment for type 1 diabetes.

20 Jun 2014

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell's energy factory. They report their findings this week in Cell.

20 Jun 2014

Study of SLC13 transporters unlocks their therapeutic potential

Researchers have provided the first functional analysis of a member of a family of transporter proteins implicated in diabetes, obesity, and lifespan. The study appears in the June issue of The Journal of General Physiology.

19 Jun 2014

Mayo Clinic study: Reversing current thought on treatment of cirrhotic patients with type 2 diabetes

Researchers at Mayo Clinic released a new study reversing current thought on the treatment of cirrhotic patients with type 2 diabetes. The study found that the continuation of metformin after a cirrhosis diagnosis improved survival rates among diabetes patients.

19 Jun 2014

U of MD researchers to use $3.7 million NIH grant to develop novel method to treat monogenic diabetes

The National Institutes of Health has awarded a four-year, $3.7 million grant to researchers at the University of Maryland School of Medicine to develop a personalized medicine program to help doctors diagnose and treat monogenic diabetes - a form of diabetes caused by a mutation in a single gene.

19 Jun 2014

Common mutation in gene with overweight results in elevated ALAT values in children

A study carried out at the Institute of Biomedicine of the University of Eastern Finland shows that a common mutation in the PNPLA3 gene combined with overweight results in elevated ALAT values in children.

18 Jun 2014

Animas' predictive algorithm technology maintains glucose above hypoglycemic levels

Animas Corporation today shared encouraging results from its predictive hypoglycemia-minimizing algorithm in development.

18 Jun 2014

Insulin News and Research

Further Reading

Mice exposed to fungicide tolyfluanid show metabolic changes

Researchers develop GI microbiome modulators to treat prediabetes and diabetes

Adults with Type 2 diabetes achieve better blood glucose control after sleeve gastrectomy surgery

Soy protein supplements do not reduce testosterone levels in men with Type 2 diabetes

70% of adults with Type 1 diabetes never use blood glucose self-monitoring devices to download historical data

Study explores new ways to improve medications to treat type 2 diabetes

Women who develop gestational diabetes perform worse on cognitive function tests

Long-term mild cold exposure can stimulate brown fat growth

Researchers shown how free radicals contribute to fatty liver disease

African American women respond differently to anti-inflammatory effect of aspirin than white women

Greenlander study identifies single mutation with large diabetes risk

Telephone-based weight loss intervention is effective in breast cancer treatments

Continuation of metformin after cirrhosis diagnosis improves survival rates in diabetes patients

New research reveals gene's role in type 1 diabetes

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

Study of SLC13 transporters unlocks their therapeutic potential

Mayo Clinic study: Reversing current thought on treatment of cirrhotic patients with type 2 diabetes

U of MD researchers to use $3.7 million NIH grant to develop novel method to treat monogenic diabetes

Common mutation in gene with overweight results in elevated ALAT values in children

Animas' predictive algorithm technology maintains glucose above hypoglycemic levels

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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