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Implanting dopamine generators in brain cells improves Parkinson's in monkeys

Implanting dopamine generators (dopaminergics) in brain cells has produced improvement in the symptoms in Parkinson's, according to the results of tests carried out with monkeys by the Navarra University Hospital, led by Dr Mar'a Rosario Luquin Piudo, neurologist at the Hospital and at the other Navarra University-based medical centre, CIMA (the Research Centre for Applied Medicine).

17 May 2007

Link between Parkinson's and narcolepsy

Parkinson's disease is well-known for its progression of motor disorders: stiffness, slowness, tremors, difficulties walking and talking.

17 May 2007

Study revises dynamin's role in nerve cell function

An unexpected finding on how nerve cells signal to one another could rewrite the textbooks on neuroscience, says a collaborative team of researchers at Weill Cornell Medical College and Yale University.

17 May 2007

Exercise shows beneficial effects in patients with Parkinson's disease

A new study from researchers at the Keck School of Medicine of the University of Southern California (USC) shows that treadmill exercises may benefit patients with Parkinson's Disease and those with similar movement disorders.

16 May 2007

Coenzyme Q10 does not improve Parkinson's disease symptoms

Small doses of the antioxidant coenzyme Q10 appear to increase blood levels of this naturally occurring compound in patients with Parkinson's disease, but does not improve Parkinson's disease symptoms, according to an article posted online today that will appear in the July 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.

15 May 2007

Scientists find new proteins involved in Huntington's disease

Researchers in the United States have identified more than 200 new proteins that are involved in Huntington's disease.

14 May 2007

Study finds large number of new proteins implicated in Huntington's disease

Researchers from four organizations have identified more than 200 new proteins that bind to normal and mutant forms of the protein that causes Huntington's disease (HD).

11 May 2007

Study provides clues about inability to imitate and empathize in autistic children

New imaging research at UCLA shows that impairments in autistic children's ability to imitate and empathize can be linked to dysfunction in the brain's mirror-neuron system.

8 May 2007

Social behavior differs in children with family history of autism

The baby brothers and sisters of autistic children do not seek emotional cues from adults, or respond to them, as often as other toddlers do, suggests new research from the University of California, San Diego.

8 May 2007

New compounds promising candidates for neurodegenerative disease drug development

Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.

8 May 2007

Multitasking mental cells

In the mid-1990s, scientists at the University of Parma, in Italy, made a discovery so novel that it shifted the way psychologists discuss the brain. After researchers implanted electrodes into the heads of monkeys, they noticed a burst of activity in the premotor cortex when the animals clutched a piece of food.

8 May 2007

Current approach to drug discovery for Lou Gehrig's disease be re-examined

Most research on Lou Gehrig's disease therapeutics has been based on the assumption that its two forms (sporadic and hereditary) are similar in their underlying cause.

8 May 2007

Antidepressants induce new nerve cell growth in the hippocampus

The growth of new nerve cells in the hippocampus has been suggested as the way antidepressants work in rodents, says Eric Nestler, MD, PhD, of the University of Texas Southwestern Medical Center.

8 May 2007

New vitamin extends lifespan in yeast cells

Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings the tantalizing possibility a step closer.

4 May 2007

Noise effects in ion channels in the brain are much larger than previously assumed

Addressing a current issue in neuroscience, Aldo Faisal and Simon Laughlin from Cambridge University investigate the reliability of thin axons for transmitting information.

4 May 2007

Study of damaged gene gives insight into causes of mental illness

Scientists have pinpointed how different types of damage in types of damage to the same gene can cause some people to suffer from schizophrenia while others have major depression.

4 May 2007

Single gene is responsible for most cool temperature sensation

The discovery, reported in the May 3 issue of the journal Neuron, might one day lead to the development of drugs that induce cold sensation as an analgesic, or block it to prevent certain forms of chronic pain associated with cold sensation.

4 May 2007

Backup brain region compensates for stroke

Researchers have pinpointed in humans how a "backup" brain region springs into action to compensate for disruption of a primary functional area, as happens during stroke.

4 May 2007

Gene malfunctions cause schizophrenia, depression symptoms in mice

Researchers have demonstrated for the first time that malfunction of a gene that had been associated with schizophrenia and depression does indeed cause symptoms of those disorders.

4 May 2007

Green tea shows potential for HIV-associated dementia prevention

A compound derived from green tea greatly diminished the neurotoxicity of proteins secreted by the human immunodeficiency virus, suggesting a new approach to the prevention and treatment of HIV-associated dementia, also known as AIDS dementia complex.

2 May 2007